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WDR45L

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Protein-coding gene in the species Homo sapiens

WDR45B
Identifiers
AliasesWDR45B, WDR45L, WIPI-3, WIPI3, WD repeat domain 45B, NEDSBAS
External IDsOMIM: 609226; MGI: 1914090; HomoloGene: 6028; GeneCards: WDR45B; OMA:WDR45B - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)
Chromosome 17 (human)Genomic location for WDR45BGenomic location for WDR45B
Band17q25.3Start82,614,562 bp
End82,648,553 bp
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)
Chromosome 11 (mouse)Genomic location for WDR45BGenomic location for WDR45B
Band11 E2|11 85.24 cMStart121,218,050 bp
End121,245,271 bp
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • epithelium of nasopharynx

  • beta cell

  • right uterine tube

  • mucosa of pharynx

  • nasal epithelium

  • gingival epithelium

  • epithelium of bronchus

  • skin of arm

  • bronchial epithelial cell
Top expressed in
  • epiblast

  • neural tube

  • ovary

  • Mesencephalon

  • placenta

  • dentate gyrus of hippocampal formation granule cell

  • granulocyte

  • ventricular zone

  • ganglionic eminence

  • heart
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

56270

66840

Ensembl

ENSG00000141580

ENSMUSG00000025173

UniProt

Q5MNZ6

Q9CR39

RefSeq (mRNA)

NM_019613

NM_025793

RefSeq (protein)

NP_062559

NP_080069

Location (UCSC)Chr 17: 82.61 – 82.65 MbChr 11: 121.22 – 121.25 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3), also known as WD repeat-containing protein 45-like is a protein that in humans is encoded by the gene.

Structure and function

WIPI-3 is a member of the WIPI or SVP1 family of WD40 repeat-containing proteins. The protein contains seven WD40 repeats that are thought to fold into a beta-propeller structure that mediates protein–protein interactions, and a conserved motif for interaction with phospholipids.

See also

References

  1. ^ GRCh38: Ensembl release 89: ENSG00000141580Ensembl, May 2017
  2. ^ GRCm38: Ensembl release 89: ENSMUSG00000025173Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: WDR45-like".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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