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{{short description|Indian biochemist, molecular biologist (born 1960)}} {{short description|Indian biochemist, molecular biologist (born 1960)}}
{{Use dmy dates|date=January 2019}} {{Use dmy dates|date=January 2019}}
{{Use Indian English|date=January 2019}} {{Use Indian English|date=January 2019}}
{{Infobox scientist {{Infobox scientist
| name = Jayant B. Udgaonkar
| image = Prof. Jayant B. Udgaonkar.jpg
| name = Jayant B. Udgaonkar | native_name = {{transl|mr|Jayanta Udgāṁvakara}}
| native_name_lang = mr
| image = Prof. Jayant B. Udgaonkar.jpg | birth_date = {{Birth date and age|1960|03|22}}
⚫ | birth_place = Maharashtra
| alt = | education = ] (MSc)
] (PhD)
| caption = | alma_mater = ] (BSc)
| organization = ], ]
| birth_date = {{Birth date and age|df=yes|1960|3|22}} | known_for = ]
| spouse = Dr. Suhasini Udgaonkar
| website = {{URL|https://sites.google.com/acads.iiserpune.ac.in/prof-udgaonkar-lab}}
⚫ | birth_place = ], India
| death_date =
| death_place =
| residence =
| nationality = ]
| fields = {{ublist | ] }}
| workplaces = {{ublist | ] | ] | ] }}
| alma_mater = {{ublist | ] (]) | ] | ] | ] }}
| doctoral_advisor = George P. Hess<br>Robert Lesh Baldwin
| doctoral_students =
| known_for = Studies on ]
| awards = 1996&nbsp;Birla Biology Award<br>2000&nbsp;]<br>2011&nbsp;] Distinguished Alumnus Award<br>2011&nbsp;] G. N. Ramachandran Gold Medal
}} }}
'''Jayant Bhalchandra Udgaonkar''' (]: {{transl|mr|Jayanta Udgāṁvakara}}) is a molecular biologist studying the processes by which a random chain of amino acids stabilises into a functional structure during or after translation.<ref>{{Cite web |title=Jayant B. Udgaonkar - IISER Pune |url=https://www.iiserpune.ac.in/research/department/biology/people/faculty/regular-faculty/jayant-b-udgaonkar/348}}</ref><ref name=felicitation>{{cite web|title=Felicitation Event Honouring Prof. Jayant B. Udgaonkar at IISER Pune |url=https://www.youtube.com/watch?v=FytNVG5cvto}}</ref>
'''Jayant Bhalchandra Udgaonkar''' (born 1960) is a former ] and ] of ]<ref>{{Cite web |title=Jayant B. Udgaonkar - IISER Pune |url=https://www.iiserpune.ac.in/research/department/biology/people/faculty/regular-faculty/jayant-b-udgaonkar/348}}</ref> at the ]. Without any major scientific contribution, he has nevertheless established himself as a prominent protein-folding scientist amongst the local scientific community (for notable contributions in the field, see ]). In 2016, the ] published a retraction notice<ref> {{cite web |date= 7 December 2021 |title=Retraction Notice to: The Pathogenic A116V Mutation Enhances Ion-Selective Channel Formation by Prion Protein in Membranes |url=https://www.cell.com/biophysj/pdf/S0006-3495(21)00952-8.pdf |access-date= 24 September 2024 |publisher= Biophysical Society}} </ref> citing evidence of manipulation via duplication, mirroring, and rescaling of identical data in one of his papers.<ref> {{cite web |date= 26 April 2016 |title=The Pathogenic A116V Mutation Enhances Ion-Selective Channel Formation by Prion Protein in Membranes |url=https://www.cell.com/action/showPdf?pii=S0006-3495%2816%2930068-6 |access-date= 24 September 2024 |publisher= Biophysical Society}} </ref>

== Biography ==
== Early Life and Education ==
] (This is not Dr. Udgaonkar`s own result).]]

⚫ Jayant Udgaonkar, born on 22 March 1960, did his studies in protein folding chemistry at ].<ref name="Profile on NCBS">{{cite web |date=2016 |title=Profile on NCBS |url=https://www.ncbs.res.in/sites/default/files/ju_cvbrief_jan16.pdf |access-date=15 October 2016 |publisher=National Centre for Biological Sciences}}</ref> Udgaonkar obtained his PhD in protein folding from ] and carried out his postdoctoral research in protein folding from ]. He propounded the protein folding hypothesis that ''initial ]'' is the first stage in protein folding, which he demonstrated using a model protein and elucidated the various stages of protein folding and unfolding. His current work focuses on formation of ].<ref name="Jayant Udgaonkar on Google Scholar">{{cite web |date=2016 |title=Jayant Udgaonkar on Google Scholar |url=https://scholar.google.ae/citations?user=UKyLWOQAAAAJ&hl=en |access-date=16 October 2016 |work=Author profile |publisher=Google Scholar}}</ref><ref name="Jayant Udgaonkar on ResearchGate">{{cite web |date=2016 |title=Jayant Udgaonkar on ResearchGate |url=https://www.researchgate.net/profile/Jayant_Udgaonkar |access-date=16 October 2016 |work=Author profile}}</ref>
Born on 22 March 1960 to Dr. ], a theoretical physicist, and Dr. Suhasini Udgaonkar, a renowned historian, Dr. Jayant Udgaonkar studied Chemistry at ] (BSc, 1979) and ] (MSc, 1981), and Biochemistry at ].<ref name="felicitation" /><ref>{{cite book |last1=Phondke |first1=Bal |url=http://www.hbcse.tifr.res.in/data/pdf/bmu/udgaonkar-confe.pdf |title=B.M. Udgaonkar: Eminent Scientist and Educationist |last2=Sheth |first2=Parul R. |last3=Naik-Satam |first3=Suhas |last4=Deshpande |first4=A.P. |date=2007 |publisher=National Center for Science Communication; Homi Bhabha Centre for Science Communication |location=Mumbai}}</ref><ref name="Profile on NCBS">{{cite web |date=2016 |title=Profile on NCBS |url=https://www.ncbs.res.in/sites/default/files/ju_cvbrief_jan16.pdf |access-date=15 October 2016 |publisher=National Centre for Biological Sciences}}</ref>

== Protein Folding ==

⚫ While studying the kinetics of ] in response to the binding of ] at ], he was struck by the structural precision of protein molecules that enabled them to perform highly specialized tasks with extreme precision. Consequently, he focused his attention on the processes that make these structures possible, and what may go wrong in these highly accurate processes. In one of his earliest studies, he found that a certain '']'' is the first stage in a typical protein folding process. His current work focuses on the formation of ]<nowiki/>s.<ref name="Jayant Udgaonkar on Google Scholar">{{cite web |date=2016 |title=Jayant Udgaonkar on Google Scholar |url=https://scholar.google.ae/citations?user=UKyLWOQAAAAJ&hl=en |access-date=16 October 2016 |work=Author profile |publisher=Google Scholar}}</ref><ref name="Jayant Udgaonkar on ResearchGate">{{cite web |date=2016 |title=Jayant Udgaonkar on ResearchGate |url=https://www.researchgate.net/profile/Jayant_Udgaonkar |access-date=16 October 2016 |work=Author profile}}</ref>


== Legacy ==
He is the son of noted scientist ].<ref>{{cite book|last1=Phondke|first1=Bal|last2=Sheth|first2=Parul R.|last3=Naik-Satam|first3=Suhas|last4=Deshpande|first4=A.P.|title=B.M. Udgaonkar: Eminent Scientist and Educationist|date=2007|publisher=National Center for Science Communication; Homi Bhabha Centre for Science Communication|location=Mumbai|url=http://www.hbcse.tifr.res.in/data/pdf/bmu/udgaonkar-confe.pdf}}</ref>
== Awards and Honors == == Awards and Honors ==
* Vigyan Shri Award under ] scheme (2024)<ref>{{cite web |title=Rashtriya Vigyan Puraskar (RVP) - 2024 : Final List of Awardees |url=https://awards.gov.in/Home/GoToIndex?filename=Award%2FCommunication%2F202488013634H24ZU2.pdf|website=awards.gov.in |publisher=CASU, Ministry of Home Affairs, Government of India |access-date=15 August 2024}}</ref><ref>{{cite news |title=Rashtriya Vigyan Puraskar: Chandrayaan-3 team and 32 others selected for first ever edition |url=https://economictimes.indiatimes.com/news/science/rashtriya-vigyan-puraskar-chandrayaan-3-team-and-32-others-selected-for-first-ever-edition-here-is-full-list/articleshow/112349033.cms?from=mdr |newspaper=The Economic Times | date=7 August 2024 |access-date=15 August 2024}}</ref> * Vigyan Shri Award under ] scheme (2024).<ref>{{cite web |title=Rashtriya Vigyan Puraskar (RVP) - 2024 : Final List of Awardees |url=https://awards.gov.in/Home/GoToIndex?filename=Award%2FCommunication%2F202488013634H24ZU2.pdf|website=awards.gov.in |publisher=CASU, Ministry of Home Affairs, Government of India |access-date=15 August 2024}}</ref><ref>{{cite news |title=Rashtriya Vigyan Puraskar: Chandrayaan-3 team and 32 others selected for first ever edition |url=https://economictimes.indiatimes.com/news/science/rashtriya-vigyan-puraskar-chandrayaan-3-team-and-32-others-selected-for-first-ever-edition-here-is-full-list/articleshow/112349033.cms?from=mdr |newspaper=The Economic Times | date=7 August 2024 |access-date=15 August 2024}}</ref>
* Udgaonkar stood first in the BSc chemistry examinations of the ] in 1979 protein folding.<ref name="Profile on NCBS" /> * Udgaonkar stood first in the BSc chemistry examinations of the ] in 1979.<ref name="Profile on NCBS" />


== Selected bibliography == == Selected bibliography ==

Revision as of 03:08, 1 January 2025

Indian biochemist, molecular biologist (born 1960)

Jayant B. Udgaonkar
Jayanta Udgāṁvakara
Born (1960-03-22) March 22, 1960 (age 64)
Maharashtra
EducationIIT Madras (MSc) Cornell University (PhD)
Alma materSt. Xavier's College, Mumbai (BSc)
Organization(s)National Centre for Biological Sciences, IISER Pune
Known forProtein-folding
SpouseDr. Suhasini Udgaonkar
Websitesites.google.com/acads.iiserpune.ac.in/prof-udgaonkar-lab

Jayant Bhalchandra Udgaonkar (Marathi: Jayanta Udgāṁvakara) is a molecular biologist studying the processes by which a random chain of amino acids stabilises into a functional structure during or after translation.

Early Life and Education

Born on 22 March 1960 to Dr. Bhalchandra Udgaonkar, a theoretical physicist, and Dr. Suhasini Udgaonkar, a renowned historian, Dr. Jayant Udgaonkar studied Chemistry at St. Xavier's College, Mumbai (BSc, 1979) and IIT Madras (MSc, 1981), and Biochemistry at Cornell University.

Protein Folding

While studying the kinetics of acetylcholine receptors in response to the binding of ACh at Stanford University, he was struck by the structural precision of protein molecules that enabled them to perform highly specialized tasks with extreme precision. Consequently, he focused his attention on the processes that make these structures possible, and what may go wrong in these highly accurate processes. In one of his earliest studies, he found that a certain hydrophobic collapse is the first stage in a typical protein folding process. His current work focuses on the formation of amyloids.

Awards and Honors

Selected bibliography

References

  1. "Jayant B. Udgaonkar - IISER Pune".
  2. ^ "Felicitation Event Honouring Prof. Jayant B. Udgaonkar at IISER Pune".
  3. Phondke, Bal; Sheth, Parul R.; Naik-Satam, Suhas; Deshpande, A.P. (2007). B.M. Udgaonkar: Eminent Scientist and Educationist (PDF). Mumbai: National Center for Science Communication; Homi Bhabha Centre for Science Communication.
  4. ^ "Profile on NCBS" (PDF). National Centre for Biological Sciences. 2016. Retrieved 15 October 2016.
  5. "Jayant Udgaonkar on Google Scholar". Author profile. Google Scholar. 2016. Retrieved 16 October 2016.
  6. "Jayant Udgaonkar on ResearchGate". Author profile. 2016. Retrieved 16 October 2016.
  7. "Rashtriya Vigyan Puraskar (RVP) - 2024 : Final List of Awardees" (PDF). awards.gov.in. CASU, Ministry of Home Affairs, Government of India. Retrieved 15 August 2024.
  8. "Rashtriya Vigyan Puraskar: Chandrayaan-3 team and 32 others selected for first ever edition". The Economic Times. 7 August 2024. Retrieved 15 August 2024.

External links

Recipients of Shanti Swarup Bhatnagar Prize for Science and Technology in Biological Science
1960s
1970s
1980s
1990s
2000s
2010s
2020s
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