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Brown tumors may be rarely associated with ectopic parathyroid adenomas.<ref>{{cite journal|last=Sharma|first=Ravi|author2=Mathan Mohan|author3=R S Neelakandan|author4=D Siddharth|title=An unusual case of brown tumor of hyperparathyroidism associated with ectopic parathyroid adenoma|journal=European Journal of Dentistry|date=October 2013|volume=7|issue=4|pages=500–503|doi=10.4103/1305-7456.120657|url=http://www.eurjdent.com/text.asp?2013/7/4/500/120657|accessdate=2013-10-28}}</ref>
Brown tumors may be rarely associated with ectopic parathyroid adenomas.<ref>{{cite journal|last=Sharma|first=Ravi|author2=Mathan Mohan|author3=R S Neelakandan|author4=D Siddharth|title=An unusual case of brown tumor of hyperparathyroidism associated with ectopic parathyroid adenoma|journal=European Journal of Dentistry|date=October 2013|volume=7|issue=4|pages=500–503|doi=10.4103/1305-7456.120657|url=http://www.eurjdent.com/text.asp?2013/7/4/500/120657|accessdate=2013-10-28}}</ref>
==Epidemiology==
Lesions are found in women and have increased incidence with age. Hyperparathyroidism with bone disease has become rare in countries due to increased use of screening laboratory examinations. In less developed countries, patients may present with hyperparathyroidism and advanced bone disease. <ref>http://path.upmc.edu/cases/case139/dx.html</ref>
==See also==
==See also==
Revision as of 18:07, 13 January 2015
Medical condition
Brown tumor
The brown tumor is a bone lesion that arises in settings of excess osteoclast activity, such as hyperparathyroidism. It is not a true neoplasm, as the term "tumor" suggests; however, it may mimic a true neoplasm. Brown tumours are radiolucent on x-ray.
Brown tumours consist of fibrous tissue, woven bone and supporting vasculature, but no matrix. The osteoclasts consume the trabecular bone that osteoblasts lay down and this front of reparative bone deposition followed by additional resorption can expand beyond the usual shape of the bone, involving the periosteum thus causing bone pain. The characteristic brown coloration results from hemosiderin deposition into the osteolytic cysts. Hemosiderin deposition is not a distinctive feature of brown tumors; it may also be seen giant cell tumors of the bone.
Brown tumors may be rarely associated with ectopic parathyroid adenomas.
Epidemiology
Lesions are found in women and have increased incidence with age. Hyperparathyroidism with bone disease has become rare in countries due to increased use of screening laboratory examinations. In less developed countries, patients may present with hyperparathyroidism and advanced bone disease.
