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| #REDIRECT ] | |||
| '''Redox signaling''' is the process wherein ], ] (ROS), and other electronically-activated species act as messengers in biological systems. | |||
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| ==History== | |||
| The concept of electronically-activated species as messengers in both normal metabolism and in pathogenesis goes back to the 19th century. For example, the biological pigment ] is a stable free radical. ] noted that white blue-eyed cats are usually deaf and that this combination might be related to some defect in neuronal development secondary to the absence of melanin pigment. In a similar manner, it has been known for centuries that radical-generating ] such as interocular ] and ] may produce massive vitreous fibrosis (scarring) as they oxidize. We now know that ] likely play a key role in fibrocyte activation. | |||
| The "Adrenochrome Hypothesis" of ] and ] for the causation of ] involves the radical oxidation of the neurotransmitter ] to the psychoactive compound ]. | |||
| ==External links== | |||
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| {{biochem-stub}} | |||
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