Talk:Pneumonia: Difference between revisions

Browse history interactively ← Previous editContent deleted Content addedVisual WikitextInline

Revision as of 00:56, 22 July 2022 editMissvain (talk \| contribs)Autopatrolled, Administrators235,517 edits OneClickArchiver archived Links about Coronavirus as cause to Talk:Pneumonia/Archive 1 ← Previous edit		Latest revision as of 03:10, 7 November 2024 edit undoRemsense (talk \| contribs)Extended confirmed users, Page movers, New page reviewers, Template editors60,029 edits →Add A Fact: "Child dies of pneumonia every 43 seconds": Closing discussion (DiscussionCloser v.1.7.3-8)
(19 intermediate revisions by 12 users not shown)
Line 1:		Line 1:
	{{skip to talk}}		{{skip to talk}}
	{{talk page header\|custom_header=This is the talk page for discussing improvements to the ] article.}}		{{talk page header\|custom_header=This is the talk page for discussing improvements to the ] article.}}
	{{Vital article\|level=3\|topic=Health and Medicine\|class=GA}}
⚫	{{banner holder\|collapsed=yes\|
	{{ArticleHistory		{{ArticleHistory
	\|action1=PR		\|action1=PR
Line 37:		Line 35:
	\|topic=Biology and medicine		\|topic=Biology and medicine
	}}		}}
			{{WikiProject banner shell\|class=GA\|vital=yes\|1=
		⚫	{{WikiProject Medicine\|importance=Top\|pulmonology=yes\|pulmonology-imp=Top\|1=\|MCOTM=cur\|selected=yes\|translation=yes\|translation-imp=Top }}
		⚫	}}
		⚫	{{banner holder\|collapsed=yes\|
	{{Backwardscopy\|title=Diseases and Disorders\|url= http://books.google.ca/books?id=zG18qk2OvlUC&pg=PA678 \|author= Julie A McDougal\| year=2007\| org= Marshall Cavendish \|comments=Extensive copy and pastes of large sections of Misplaced Pages without appropriate attribution or release under the appropriate license.}}		{{Backwardscopy\|title=Diseases and Disorders\|url= http://books.google.ca/books?id=zG18qk2OvlUC&pg=PA678 \|author= Julie A McDougal\| year=2007\| org= Marshall Cavendish \|comments=Extensive copy and pastes of large sections of Misplaced Pages without appropriate attribution or release under the appropriate license.}}
		⚫	}}{{annual readership\|scale=log}}
⚫	}}
	{{WikiProjectBannerShell\|1=
⚫	{{~~WPMED\|class=GA~~\|importance=Top\|pulmonology=yes\|pulmonology-imp=Top\|\|MCOTM=cur\|selected=yes\|translation=yes \|translation-imp=Top }}
	{{WP1.0\|WPCD=y}}
⚫	}}
⚫	{{annual readership\|scale=log}}
	{{Reliable sources for medical articles}}		{{Reliable sources for medical articles}}

Line 56:		Line 53:
	}}		}}
	{{Archive box \|search=yes \|bot=Lowercase sigmabot III \|age=12 \|units=months \|auto=yes }}		{{Archive box \|search=yes \|bot=Lowercase sigmabot III \|age=12 \|units=months \|auto=yes }}

	== "Necrotizing pneumonia" listed at ] ==
	]
	An editor has asked for a discussion to address the redirect ]. Please participate in ] if you wish to do so. <!-- from Template:RFDNote --> ''' —''' ] (]) (])  01:42, 29 April 2020 (UTC)

	== Limitations on diagnosis ==

	{{u\|Mikalra}} added the Jain 2015 NEJM study which showed the limitations of advanced diagnostics in determining the aetiology of CAP (]). This study, while groundbreaking, does not comply with ]. Currently the observation on this problem is cited in the body of the article to a source called EBMED05, which is now 15 years old and should be updated in line with MEDRS.

	Oddly the updated ATS guideline does not discuss the poor yield of investigations, but the Jain study is cited in ]. I'm sure this would be a good alternative to EBMED05 for this information as well as some other bits. ] \| ] 14:47, 1 September 2020 (UTC)

	:This study didn't use 'advanced diagnostics,' but routine laboratory diagnostics such as PCR and urinary antigen testing. You're right that "the observation on this problem is cited in the body of the article to a source called EBMED05;" the Jain study is an example of that problem and is a large and relatively recent report in institutions equipped to address the question.] (]) 15:54, 1 September 2020 (UTC)

	For many healthcare settings, the diagnostics used in Jain2015 were definitely "advanced". In the UK the viral PCR panel in pneumonia only includes influenza and RSV unless the host is immunocompromised. ] \| ] 15:01, 2 September 2020 (UTC)

	:{{ping\|Mikalra}} The Jain 2015 reference is not an appropriate source, so it has been removed again. Please review ] for explanation. ] \| ] 11:13, 3 September 2020 (UTC)

	== Semi-protected edit request on 21 November 2020 ==

	{{edit semi-protected\|Pneumonia\|answered=yes}}
	I would like to enhance this page's coverage of the robustly established relationship between SARS-CoV-2 and pneumonia.

	Change "Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can also result in pneumonia."

	to

	"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can also result in pneumonia. The virus infects and destroys the cells of the alveoli, both those that are ciliated and those that produce mucus and surfactant <ref>https://www.seattletimes.com/seattle-news/health/facts-about-novel-coronavirus-and-how-to-prevent-covid-19/</ref>. Because the cilia cannot function properly, fluid and cellular debris accumulate in the alveoli, which can cause pneumonia <ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373339/</ref><ref>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431901/</ref>. ] (]) 02:06, 21 November 2020 (UTC)

	:This can only be supported with very high quality references. A newspaper article would not be sufficient, nor an animal study. The pathogenesis is probably more complicated than you have indicated: there is diffuse alveolar damage and immunothrombosis. Hence not supporting this addition at this time. ] \| ] 21:27, 21 November 2020 (UTC)

	{{Reflist-talk}}

	== Please harmonize the internal contradiction about the cause of pneumonia ==

	In the '''Cause''' section you cite , a paper which puts viruses well ahead of bacteria in causing pneumonia. Later, in the '''Bacteria''' section you state that "Bacteria are the most common cause" with a different reference (#35 Sharma 2007), putting a direct contradiction into this article, just a few lines

	PS: Just as in the telephone game the numbers have been misquoted. It says "20% haemophilus" but it was 20 cases or 7% in the original paper!
	::Good catch here @JS. I can help make this edit. As for the review article, this is one of differences between medical writing on Misplaced Pages and writing for a peer-reviewed medical journal- the use of the ] guideline preferring high-quality secondary sources to primary research sources. It is not always perfect- i.e.- susceptibilty to the 'telephone game' errors, however, some feel that there are strengths as well to this approach given that anyone can edit these articles. I will not have time to review the citations for a few days, but will try to circle back soon. Citations to consider: Primary source, presently ref # 28 Jain et al 2015. <ref>{{Cite journal\|last=Jain\|first=Seema\|last2=Self\|first2=Wesley H.\|last3=Wunderink\|first3=Richard G.\|last4=Fakhran\|first4=Sherene\|last5=Balk\|first5=Robert\|last6=Bramley\|first6=Anna M.\|last7=Reed\|first7=Carrie\|last8=Grijalva\|first8=Carlos G.\|last9=Anderson\|first9=Evan J.\|last10=Courtney\|first10=D. Mark\|last11=Chappell\|first11=James D.\|date=2015-07-30\|title=Community-Acquired Pneumonia Requiring Hospitalization among U.S. Adults\|url=https://pubmed.ncbi.nlm.nih.gov/26172429\|journal=The New England Journal of Medicine\|volume=373\|issue=5\|pages=415–427\|doi=10.1056/NEJMoa1500245\|issn=1533-4406\|pmc=4728150\|pmid=26172429}}</ref>. Outdated secondary source (does not meet ]):<ref>{{Cite journal\|last=Sharma\|first=Sat\|last2=Maycher\|first2=Bruce\|last3=Eschun\|first3=Gregg\|date=May, 2007\|title=Radiological imaging in pneumonia: recent innovations\|url=https://pubmed.ncbi.nlm.nih.gov/17414122\|journal=Current Opinion in Pulmonary Medicine\|volume=13\|issue=3\|pages=159–169\|doi=10.1097/MCP.0b013e3280f3bff4\|issn=1070-5287\|pmid=17414122}}</ref> ] (]) 16:39, 22 November 2021 (UTC)
	:::P.S- if anyone wants to beat me to this improvement please do go ahead!!! There are a lot of outdated references in the aforementioned sections. ] (]) 16:46, 22 November 2021 (UTC)

	{{reflist-talk}}

	== Keiko died from this! This is for real!!! ==

	Here is the whale Keiko of the free willy movie, it DOES exist as a disease in wild animals!
	"Killer whale Keiko dies of pneumonia.." The Free Library. 2003 The Register Guard 19 Mar. 2022 https://www.thefreelibrary.com/Killer+whale+Keiko+dies+of+pneumonia.-a0112803638
⚫	--] (]) 11:50, 19 ~~March~~ ~~2022~~ (UTC)

	== Semi-protected edit request on 10 May 2022 - Genetics of Pneumonia ==		== Semi-protected edit request on 10 May 2022 - Genetics of Pneumonia ==
Line 136:		Line 86:
	{{Reflist}} ] (]) 00:26, 11 May 2022 (UTC)		{{Reflist}} ] (]) 00:26, 11 May 2022 (UTC)
	: ] '''Not done:''' it's not clear what changes you want to be made. Please mention the specific changes in a "change X to Y" format and provide a ] if appropriate.<!-- Template:ESp --> —](]) 05:46, 14 May 2022 (UTC)		: ] '''Not done:''' it's not clear what changes you want to be made. Please mention the specific changes in a "change X to Y" format and provide a ] if appropriate.<!-- Template:ESp --> —](]) 05:46, 14 May 2022 (UTC)

			== ] ==

			On Misplaced Pages there are 5 links to "]" which then redirects here, yet "hypostatic" does not appear anywhere within this article. The disambiguation for ] only gives one medically relevant definition: "Hypostasis ''(])'', corpse's discoloration". That might be helpful, but it's for a different organ. I can only take an educated guess at what hypostatic pneumonia means, and I wouldn't be sure the right place to describe it if I knew. ] (]) 20:12, 26 September 2022 (UTC)

			== ''Cause'' section should probably be updated to take into account the prevalence of SARS-CoV-2 amongst pneumoniae causes ==

			This is important because such beliefs may lead the public to not consiser SARS-CoV-2 as a potential cause of pneumonia and lead to unjustified intakes of antibiotics. ] (]) 06:09, 29 September 2023 (UTC)

			== Is pneumonia the same as asthma? ==

			No, they're different as ] is a ] and can cause ] , but ] is a disease of the ]; filling the ] with a fluid and can result a cause of death, for more information, watch the ] video or search the article ]. Also the article ]
		⚫	] (]) 11:20, 8 April 2024 (UTC)

			== Add A Fact: "Child dies of pneumonia every 43 seconds" ==
			{{atop
			\| result = {{nd}}—I will go out on a limb to say this is the type of statistic that generally tugs the heartstrings more than it meaningfully educates. It would be an unencyclopedic addition. <span style="border-radius:2px;padding:3px;background:#1E816F">]<span style="color:#fff"> ‥ </span>]</span> 03:10, 7 November 2024 (UTC)
		⚫	}}

			I found a fact that might belong in this article. See the quote below
			<blockquote>
			A child dies of pneumonia every 43 seconds
			</blockquote>
			The fact comes from the following source:
			: https://data.unicef.org/topic/child-health/pneumonia/


			Additional comments from user: It is alarming how these illnesses affect children, highlighting the urgent need to prevent and reverse the current situation.

			This post was generated using the ] browser extension.

			] (]) 16:37, 5 November 2024 (UTC)
			{{abot}}

Latest revision as of 03:10, 7 November 2024

Skip to table of contents

This is the talk page for discussing improvements to the Pneumonia article.

Put new text under old text. Click here to start a new topic.
New to Misplaced Pages? Welcome! Learn to edit; get help.

Article policies

Find medical sources: Source guidelines · PubMed · Cochrane · DOAJ · Gale · OpenMD · ScienceDirect · Springer · Trip · Wiley · TWL

Archives: 1Auto-archiving period: 12 months

Pneumonia is a former featured article. Please see the links under Article milestones below for its original nomination page (for older articles, check the nomination archive) and why it was removed.

Pneumonia has been listed as one of the Natural sciences good articles under the good article criteria. If you can improve it further, please do so. If it no longer meets these criteria, you can reassess it.

This article appeared on Misplaced Pages's Main Page as Today's featured article on December 4, 2005.

Article milestones
Date	Process	Result
September 19, 2005	Peer review	Reviewed
November 9, 2005	Peer review	Reviewed
November 19, 2005	Featured article candidate	Promoted
August 17, 2009	Featured article review	Demoted
November 25, 2012	Good article nominee	Listed
Current status: Former featured article, current good article

This

level-3 vital article is rated GA-class on Misplaced Pages's content assessment scale.
It is of interest to the following WikiProjects:

Medicine: Translation / Pulmonology Top‑importance

	Medicine portal This article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Misplaced Pages talk:WikiProject Medicine.MedicineWikipedia:WikiProject MedicineTemplate:WikiProject Medicinemedicine
Top	This article has been rated as Top-importance on the project's importance scale.
	This article is supported by the Translation task force (assessed as Top-importance).
	This article is supported by the Pulmonology task force (assessed as Top-importance).
	This article was selected on the Medicine portal as one of Misplaced Pages's best articles related to Medicine.
	This article is currently the Medicine Collaboration of the Month.

Other talk page banners

This article is substantially duplicated by a piece in an external publication. Since the external publication copied Misplaced Pages rather than the reverse, please do not flag this article as a copyright violation of the following source:

Julie A McDougal (2007), Diseases and Disorders, Marshall Cavendish

Additional comments
Extensive copy and pastes of large sections of Misplaced Pages without appropriate attribution or release under the appropriate license.

Ideal sources for Misplaced Pages's health content are defined in the guideline Misplaced Pages:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Pneumonia.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

Archives

This page has archives. Sections older than 365 days may be automatically archived by Lowercase sigmabot III when more than 10 sections are present.

Semi-protected edit request on 10 May 2022 - Genetics of Pneumonia

This edit request has been answered. Set the |answered= or |ans= parameter to no to reactivate your request.

It has been found that vulnerability to Pneumonia and its severity may be linked to underlying genetic mechanisms. These mechanisms, such as the CYP1A1 gene (CYP1A1) regulating inflammatory responses and sepsis, can influence the efficacy of the immune system which can either be detrimental or beneficial in combating Pneumonia.

Individuals with certain genetic variants can be at risk for a higher susceptibility to Pneumonia. For example, individuals with mutations in Bruton’s tyrosine kinase (BTK). These mutations lead to the development of a disease called X-linked agammaglobulinemia which inhibits the formation of white blood cells and mature B cells. Without functional BTK, the development cycle of B lymphocytes is stopped at the pre-B cell stage which results in the loss of mature lymphocytes in the bone marrow and lymphatic system. In BTK, the mutation of arg525 to gln was particularly responsible for the lowered functionality of BTK. Due to decreased white blood cell count, this immune deficiency increases one’s susceptibility to Pneumonia greatly.

A broad mapping study aimed at identifying loci associated with pulmonary function and Pneumonia in humans mapped 137 loci of interest. 116 of the 137 loci were found to be responsible for both pulmonary function and susceptibility to Pneumonia. Furthermore, 336/340 SNPs were shared between Pneumonia and pulmonary function . Genes that are responsible for pulmonary function play an integral role in overall lung development and inflammation pathways that are key to an immune response. Individuals with an impaired pulmonary function due to certain predisposed developmental, inflammatory, or cardiovascular traits were found to be at a higher risk for Pneumonia. This high degree of overlap of genes and the correlation between pulmonary function traits and susceptibility to Pneumonia could mean that there is a major genetic factor.

There are nine disease genes currently known to increase susceptibility to idiopathic interstitial Pneumonia. Three of the disease genes are responsible for the production of surfactant by alveoli in the lungs: Surfactant protein C (SFTPC), Surfactant protein A2 (SFTPA2), and Adenosine triphosphate-binding cassette subfamily A member 3 (ABCA3). Surfactant is a mixture of proteins and fats that helps keep the alveoli from collapsing when a person exhales and also protects lung cells from infection. Mutations at these loci have age-dependent effects, however, it is not yet possible to predict which family members will develop Pneumonia at what age. The other six disease genes are associated with telomeres: Telomerase reverse transcriptase , Telomerase RNA component , Dyskerin , Telomere repeat binding factor 1-interacting nuclear factor 2 , Regulator of telomere elongation helicase , Poly(A)-specific ribonuclease . Mutations in these genes impede the ability of the body to repair damage in the telomeres of chromosomes and thus they become shorter, which can also increase the risk of developing Pneumonia, amongst many other diseases. Currently, doctors do offer genetic testing for these 9 disease genes in cases where two or more individuals in the same family have Pneumonia.

During the COVID-19 pandemic, patients infected with COVID-19 were found to have twice the risk of developing pneumonia. Doctors have developed a DNA test that uses multiple polymerase chain reactions to detect DNA and antibiotic resistance of streptococcus pneumoniae in a patient’s blood sample. This can be done in the span of four hours which is much quicker than the conventional method of growing bacterial cultures which is prone to false negatives due to patients receiving antibiotics before the sample is collected. The test expedites the treatment procedure with doctors being able to prescribe antibiotics at an earlier stage and making it more effective in the treatment of Pneumonia.

References

Chen, Shaw, Petty, North. (2020, December 11). Host genetic effects in Pneumonia. Cell. https://www.cell.com/ajhg/fulltext/S0002-9297(20)30446-8

Genetics in community-acquired Pneumonia : Current Opinion in Pulmonary Medicine. (2019). LWW. https://journals.lww.com/co-pulmonarymedicine/Abstract/2019/05000/Genetics_in_community_acquired_Pneumonia.17.aspx

ILD Colaborative. (2020). Genetics of Familial Idiopathic Interstitial Pneumonia. https://www.ildcollaborative.org/resources/genetics-of-familial-idiopathic-interstitial-Pneumonia

Khadzhieva, Kuzovlev, Salnikova. (2019, December). Pneumonia: host susceptibility and shared genetics with pulmonary function and other traits. PubMed. https://pubmed.ncbi.nlm.nih.gov/31487037/

Kropski, YOung, Cogan, Mitchell, Lancaster, Worrell, Markin, Liu. (2017, June 1). Genetic Evaluation and Testing of Patients and Families with Idiopathic Pulmonary Fibrosis. National Library of Medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470751/

Waterer, Wunderink. (2010). Genetic susceptibility to Pneumonia. PubMed. https://pubmed.ncbi.nlm.nih.gov/15802163/

Guin, Debleena, et al. “Human Genetic Factors Associated with Pneumonia Susceptibility, a Cue for Covid-19 Mortality.” MedRxiv, Cold Spring Harbor Laboratory Press, 1 Jan. 2021, https://www.medrxiv.org/content/10.1101/2021.06.03.21258106v1.full.

“DNA Test Can Quickly Identify Pneumonia in Patients with Severe COVID-19, Aiding Faster Treatment.” ScienceDaily, ScienceDaily, 15 Jan. 2021, https://www.sciencedaily.com/releases/2021/01/210115091340.htm.

Guin, Debleena, et al. “Human Genetic Factors Associated with Pneumonia Susceptibility, a Cue for Covid-19 Mortality.” MedRxiv, Cold Spring Harbor Laboratory Press, 1 Jan. 2021, https://www.medrxiv.org/content/10.1101/2021.06.03.21258106v1.full.
Genetics in community-acquired Pneumonia : Current Opinion in Pulmonary Medicine. (2019). LWW. https://journals.lww.com/co-pulmonarymedicine/Abstract/2019/05000/Genetics_in_community_acquired_Pneumonia.17.aspx
Chen, Shaw, Petty, North. (2020, December 11). Host genetic effects in Pneumonia. Cell. https://www.cell.com/ajhg/fulltext/S0002-9297(20)30446-8
Khadzhieva, Kuzovlev, Salnikova. (2019, December). Pneumonia: host susceptibility and shared genetics with pulmonary function and other traits. PubMed. https://pubmed.ncbi.nlm.nih.gov/31487037/
Khadzhieva, Kuzovlev, Salnikova. (2019, December). Pneumonia: host susceptibility and shared genetics with pulmonary function and other traits. PubMed. https://pubmed.ncbi.nlm.nih.gov/31487037/
ILD Colaborative. (2020). Genetics of Familial Idiopathic Interstitial Pneumonia. https://www.ildcollaborative.org/resources/genetics-of-familial-idiopathic-interstitial-Pneumonia
ILD Colaborative. (2020). Genetics of Familial Idiopathic Interstitial Pneumonia. https://www.ildcollaborative.org/resources/genetics-of-familial-idiopathic-interstitial-Pneumonia
Kropski, YOung, Cogan, Mitchell, Lancaster, Worrell, Markin, Liu. (2017, June 1). Genetic Evaluation and Testing of Patients and Families with Idiopathic Pulmonary Fibrosis. National Library of Medicine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470751/
“DNA Test Can Quickly Identify Pneumonia in Patients with Severe COVID-19, Aiding Faster Treatment.” ScienceDaily, ScienceDaily, 15 Jan. 2021, https://www.sciencedaily.com/releases/2021/01/210115091340.htm.

Editor3456123123 (talk) 00:26, 11 May 2022 (UTC)

Not done: it's not clear what changes you want to be made. Please mention the specific changes in a "change X to Y" format and provide a reliable source if appropriate. —Sirdog (talk) 05:46, 14 May 2022 (UTC)

Hypostatic pneumonia

On Misplaced Pages there are 5 links to "hypostatic pneumonia" which then redirects here, yet "hypostatic" does not appear anywhere within this article. The disambiguation for hypostasis only gives one medically relevant definition: "Hypostasis (livor mortis), corpse's discoloration". That might be helpful, but it's for a different organ. I can only take an educated guess at what hypostatic pneumonia means, and I wouldn't be sure the right place to describe it if I knew. DAVilla (talk) 20:12, 26 September 2022 (UTC)

Cause section should probably be updated to take into account the prevalence of SARS-CoV-2 amongst pneumoniae causes

This is important because such beliefs may lead the public to not consiser SARS-CoV-2 as a potential cause of pneumonia and lead to unjustified intakes of antibiotics. MathieuSchopfer (talk) 06:09, 29 September 2023 (UTC)

Is pneumonia the same as asthma?

No, they're different as asthma is a difficulty for breathing and can cause tiredness , but pneumonia is a disease of the lungs; filling the alveolus with a fluid and can result a cause of death, for more information, watch the Videowiki/Pneumonia video or search the article Pneumonia. Also the article Asthma 112.198.178.96 (talk) 11:20, 8 April 2024 (UTC)

Add A Fact: "Child dies of pneumonia every 43 seconds"

Not done—I will go out on a limb to say this is the type of statistic that generally tugs the heartstrings more than it meaningfully educates. It would be an unencyclopedic addition. Remsense ‥ 论 03:10, 7 November 2024 (UTC)

The following discussion is closed. Please do not modify it. Subsequent comments should be made on the appropriate discussion page. No further edits should be made to this discussion.

I found a fact that might belong in this article. See the quote below

A child dies of pneumonia every 43 seconds

The fact comes from the following source:

https://data.unicef.org/topic/child-health/pneumonia/

Additional comments from user: It is alarming how these illnesses affect children, highlighting the urgent need to prevent and reverse the current situation.

This post was generated using the Add A Fact browser extension.

Laiasolagonzalez (talk) 16:37, 5 November 2024 (UTC)

The discussion above is closed. Please do not modify it. Subsequent comments should be made on the appropriate discussion page. No further edits should be made to this discussion. Categories: