Revision as of 16:26, 23 March 2007 view sourceDiscospinster (talk | contribs)Administrators464,323 editsm Reverted edits by 137.85.253.2 to last version by Despres← Previous edit | Latest revision as of 05:09, 23 December 2024 view source Citation bot (talk | contribs)Bots5,408,942 edits Altered pages. Formatted dashes. | Use this bot. Report bugs. | Suggested by Dominic3203 | Category:Cooling technology | #UCB_Category 149/157 | ||
Line 1: | Line 1: | ||
{{short description|Freezing of a corpse with the intent of future revival}} | |||
'''Cryonics''' (often mistakenly called "]") is the practice of ] ]s or animals that can no longer be sustained by contemporary ] until resuscitation may be possible in the future. The largest current practitioners are two member-owned, non-profit organizations, the ] in ], ], with 74 cryopreserved patients and the ] in ], ] with 78. | |||
{{pp-protected|small=yes}} | |||
{{for multi|the study of the production of very low temperatures|Cryogenics|the low-temperature preservation of living tissue and organisms in general|Cryopreservation|the Hot Cross album|Cryonics (album)}} | |||
{{Use dmy dates|date=October 2021}} | |||
] | |||
'''Cryonics''' (from {{langx|el|κρύος}} ''kryos'', meaning "cold") is the ] (usually at {{cvt|−196|C|F K|disp=or}}) and storage of human remains in the hope that ] may be possible in the future.<ref name="guardian cold facts">{{cite news|last=McKie|first=Robin|title=Cold facts about cryonics|url=https://www.theguardian.com/education/2002/jul/14/medicalscience.science|access-date=1 December 2013|newspaper=]|date=13 July 2002|quote="Cryonics, which began in the Sixties, is the freezing – usually in liquid nitrogen – of human beings who have been legally declared dead. The aim of this process is to keep such individuals in a state of refrigerated limbo so that it may become possible in the future to resuscitate them, cure them of the condition that killed them, and then restore them to functioning life in an era when medical science has triumphed over the activities of the Grim Reaper."|archive-date=8 July 2017|archive-url=https://web.archive.org/web/20170708232125/https://www.theguardian.com/education/2002/jul/14/medicalscience.science|url-status=live}}</ref><ref name="guardian keep cool">{{cite news|title=Dying is the last thing anyone wants to do – so keep cool and carry on|url=https://www.theguardian.com/science/2015/oct/11/cryonics-booms-in-us|work=]|date=10 October 2015 |access-date=21 February 2016 |archive-date=3 July 2017|archive-url=https://web.archive.org/web/20170703042900/https://www.theguardian.com/science/2015/oct/11/cryonics-booms-in-us|url-status=live}}</ref> Cryonics is regarded with ] by the mainstream ]. It is generally viewed as a ],<ref name=jk/> and its practice has been characterized as ].<ref name=butler/><ref name=q/> | |||
The process is not currently reversible. In the United States, Cryonics can only be legally performed on humans after ], and a legal determination that further medical care is not appropriate (]). The rationale for cryonics is that the process may be reversible in the future if performed soon enough, and that ] people may not really be dead by standards of future medicine (see ]). | |||
Cryonics procedures can begin only after the "patients" are ] and ]. Procedures may begin within minutes of death,<ref>{{cite book |last1=Hendry |first1=Robert |last2=Crippen |first2=David |chapter=Brain Failure and Brain Death |chapter-url=https://www.researchgate.net/publication/260930585 |url-status=live |title=ACS Surgery: Principles and Practice critical care |publisher=Decker Intellectual Properties Inc. |year=2014 |pages=1–10 |quote=A physician will pronounce a patient using the usual cardiorespiratory criteria, whereupon the patient is legally dead. Following this pronouncement, the rules pertaining to procedures that can be performed change radically because the individual is no longer a living patient but a corpse. In the initial cryopreservation protocol, the subject is intubated and mechanically ventilated, and a highly efficient mechanical cardiopulmonary resuscitation device reestablishes circulation. |access-date=2016-03-03 |archive-url=https://web.archive.org/web/20210123132947/https://www.researchgate.net/publication/260930585_ACS_Surgery_Principles_and_Practice_critical_care |archive-date=2021-01-23}}</ref> and use ]s to try to prevent ice formation during cryopreservation.<ref name="pmid18321197">{{cite journal |author=Best BP |title=Scientific justification of cryonics practice |journal=Rejuvenation Research |volume=11 |issue=2 |pages=493–503 |date=April 2008 |url=http://www.benbest.com/cryonics/Scientific_Justification.pdf |pmid=18321197 |pmc=4733321 |doi=10.1089/rej.2008.0661 |access-date=2013-12-26 |archive-url=https://web.archive.org/web/20180721234934/http://www.benbest.com/cryonics/Scientific_Justification.pdf |archive-date=2018-07-21 |url-status=dead}}</ref>{{bsn|date=January 2023}} It is not possible to reanimate a corpse that has undergone ], as that damages the brain, including its ].<ref name=popsicle/><ref>{{cite web|url=https://www.theguardian.com/science/2016/nov/18/the-cryonics-dilemma-will-deep-frozen-bodies-be-fit-for-new-life|title=The cryonics dilemma: will deep-frozen bodies be fit for new life?|last=Devlin|first=Hannah|author-link=Hannah Devlin|date=18 November 2016|work=The Guardian|access-date=21 January 2019|archive-date=24 January 2019|archive-url=https://web.archive.org/web/20190124164111/https://www.theguardian.com/science/2016/nov/18/the-cryonics-dilemma-will-deep-frozen-bodies-be-fit-for-new-life|url-status=live}}</ref> The first corpse to be frozen was that of ], in 1967.<ref>{{cite web |url=http://www.galenpress.com/extras/extra32.htm|title=Death To Dust: What Happens To Dead Bodies? 2nd Edition, Chapter 7: Souls On Ice|access-date=2016-03-21 |archive-date=2019-03-27|archive-url=https://web.archive.org/web/20190327102728/https://galenpress.com/extras/extra32.htm|url-status=live}}</ref> As of 2014, about 250 bodies had been cryopreserved in the ], and 1,500 people had made arrangements for cryopreservation of their remains.<ref name="moen">{{cite journal |author=Moen, OM |title=The case for cryonics |journal=] |volume=41 |issue=18 |pages=493–503 |date=August 2015 |pmid=25717141 |s2cid=31744039 |doi=10.1136/medethics-2015-102715}}</ref> | |||
Cryonics is viewed with ] by many scientists and doctors today. However, there is a high representation of scientists among cryonics supporters.<ref>{{cite web | |||
| url = http://www.cryoletter.org/ | |||
| title = Scientists' Open Letter on Cryonics | |||
| accessdate = 2006-03-17}}</ref> Scientific support for cryonics is based on projections of future technology, especially ] and ]. Some scientists believe that future medicine<ref>{{cite book | |||
| url = http://www.alcor.org/Library/html/24thcenturymedicine.html | |||
| last = Donaldson | |||
| first = Thomas | |||
| title = 24th Century Medicine | |||
| publisher = Davis Publications | |||
| year = 1988 | |||
| accessdate = 2006-03-17}}</ref> will enable ]-level repair and regeneration of damaged ]s and ]s decades or centuries in the future. ] and ] are also assumed to be reversible. | |||
Economic considerations make it difficult for cryonics corporations to remain in business long enough to take advantage of any long-term benefits.<ref name=decline/> The "patients", being dead, cannot continue to pay for their own preservation. Early attempts at cryonic preservation were made in the 1960s and early 1970s; most relied on family members to pay for the preservation and ended in failure, with all but one of the corpses cryopreserved before 1973 thawed and disposed of.<ref name=hta-law/> | |||
The central premise of cryonics is that ], ], and ] are stored in the structure and chemistry of the ]. While this view is widely accepted in ], and ] activity is known to stop and later resume under certain conditions, it is not generally accepted that current methods preserve the ] well enough to permit revival in the future. Cryonics advocates point to studies showing that high concentrations of ] circulated through the ] before cooling can largely prevent freezing injury, preserving the fine ] structures of the ] in which ] and ] presumably reside.<ref>{{cite book | |||
| url = http://www.alcor.org/Library/html/braincryopreservation1.html | |||
| accessdate = 2006-03-17 | |||
| title = Effect of Human Cryopreservation Protocol on the Ultrastucture of the Canine Brain | |||
| last = Platt | |||
| first = Charles | |||
| publisher = Alcor Life Extension Foundation | |||
| year = 1995 | |||
| work = CryoCare Report | |||
| edition = 4}}</ref> | |||
==Conceptual basis== | |||
To its detractors, the justification for the actual practice of cryonics is unclear, given present limitations of preservation technology. Currently cells, tissues, blood vessels, and some small animal organs can be reversibly ]. Some ]s can survive for a few months in a partially frozen state a few degrees below freezing, but this is not true ]. Cryonics advocates counter that demonstrably reversible preservation is not necessary to achieve the present-day goal of cryonics, which is preservation of basic ] information that encodes ] and ]. Preservation of this information is said to be sufficient to prevent ] until future repairs might be possible. | |||
Cryonicists argue that as long as brain structure remains intact, there is no fundamental barrier, given our current understanding of physics, to recovering its information content. Cryonics proponents go further than the mainstream ] in saying that the brain does not have to be continuously active to survive or retain memory. Cryonicists controversially say that a human can survive even within an inactive, badly damaged brain, as long as the original encoding of memory and personality can be adequately inferred and reconstituted from what remains.<ref name="moen" /><ref>{{cite journal|author=Doyle, DJ|date=2012|title=Cryonic Life Extension: Scientific Possibility or Stupid Pipe Dream?|journal=Ethics in Biology, Engineering and Medicine|volume=3|issue=1–3|pages=9–28|doi=10.1615/EthicsBiologyEngMed.2013006985}}</ref> | |||
Cryonics uses temperatures below −130 ], called ], in an attempt to preserve enough brain information to permit the revival of the cryopreserved person. Cryopreservation is accomplished by freezing with or without ] to reduce ice damage, or by ] to avoid ice damage. Even using the best methods, cryopreservation of whole bodies or brains is very damaging and irreversible with current technology. | |||
Probably the most famous ] is ] player ]. The popular ] that ] was cryopreserved is false; he was cremated, and interred at ]. ], who ] of the concept, was cremated and his ashes distributed over the ]. ] was a long-time cryonics advocate, and signed up with a major cryonics provider. He changed his mind, however, shortly before his death, and so was not cryopreserved. | |||
Cryonicists call the human remains packed into low-temperature vats "patients".<ref>{{cite journal | journal=Smithsonian Magazine| vauthors=Germain J | title=200 Frozen Heads and Bodies Await Revival at This Arizona Cryonics Facility | date=21 October 2022 | url=https://www.smithsonianmag.com/smart-news/200-frozen-heads-and-bodies-await-revival-at-this-arizona-cryonics-facility-180980981/ }}</ref> They hope that some kind of presently nonexistent ] will be able to bring the dead back to life and treat the diseases that killed them.<ref>{{cite journal |last1=Crippen |first1=DW |last2=Whetstine |first2=L |title=Ethics review: Dark angels – the problem of death in intensive care |journal=Critical Care |volume=11 |issue=1 |page=202 |year=2007 | pmid=17254317 |pmc=2151911 |doi=10.1186/cc5138 |doi-access=free}}</ref> ] has also been proposed.<ref>{{cite news|title=Frozen in time: Oregon firm preserves bodies, brains in hopes that science catches up |url=http://portlandtribune.com/pt/9-news/293801-170586-frozen-in-time-oregon-firm-preserves-bodies-brains-in-hopes-that-science-catches-up|access-date=February 21, 2016|work=]|date=18 February 2016|archive-date=July 11, 2017|archive-url=https://web.archive.org/web/20170711171113/http://portlandtribune.com/pt/9-news/293801-170586-frozen-in-time-oregon-firm-preserves-bodies-brains-in-hopes-that-science-catches-up|url-status=live}}</ref> | |||
==Obstacles to success== | |||
===Damage from ice formation and ischemia=== | |||
Cryonics has traditionally been dismissed by mainstream ], of which it is arguably a part. The reason generally given for this dismissal is that the ] process creates ] crystals, which some scientists have claimed damage cells and cellular structures so as to render any future repair impossible. Cryonicists have long argued, however, that the extent of this damage was greatly exaggerated by the critics, presuming that some reasonable attempt is made to perfuse the body with ] chemicals (traditionally ]) that inhibit ice crystal formation. | |||
==Cryonics in practice== | |||
According to cryonicists, the ice crystal damage objection became moot around the turn of the millennium, when cryobiologists ] and ], of ], developed major improvements in cryopreservation technology, including new ]s and new cryoprotectant mixtures, greatly improving the feasibility of ], and resulting in the near-elimination of ice crystal formation in the brain. ] preserves tissue in a glassy rather than frozen state. In ], molecules do not rearrange themselves into grainy crystals as they are cooled, but instead become locked together while still randomly arranged as in a fluid, forming a "solid liquid" as the temperature falls below the glass transition temperature. ] has since been researching the use of these cryoprotectants, along with a new, faster cooling method, to vitrify whole human brains (]). The ] (CI), uses a vitrification solution developed by its in-house ], Dr. Yuri Pichugin. CI has developed computer-controlled cooling boxes to ensure that cooling is rapid above T<SUB>g</SUB> (], solidification temperature) and slow below T<SUB>g</SUB> (to reduce fracturing due to thermal ]). | |||
Cryonics can be expensive. {{asof|2018}}, the cost of preparing and storing corpses using cryonics ranged from US$28,000 to $200,000.<ref name=hta-cost>{{cite web |publisher=] |title=Things to consider when making your decision on cryonics |url=https://www.hta.gov.uk/things-consider-when-making-your-decision-cryonics |date=26 September 2018 |access-date=3 October 2019 |archive-date=30 September 2019 |archive-url=https://web.archive.org/web/20190930062932/https://www.hta.gov.uk/things-consider-when-making-your-decision-cryonics |url-status=live}}</ref> | |||
At high concentrations, ] can stop ice formation completely. Cooling and solidification without ] formation is called ].<ref>{{cite journal|vauthors=Fahy GM, MacFarlane DR, Angell CA, Meryman HT|date=August 1984|title=Vitrification as an approach to cryopreservation|journal=Cryobiology|volume=21|issue=4|pages=407–26|doi=10.1016/0011-2240(84)90079-8|pmid=6467964}}</ref> In the late 1990s, ] ] and ] developed the first cryoprotectant solutions that could vitrify at very slow cooling rates while still allowing whole organ survival, for the purpose of banking transplantable organs.<ref name="Fahy GM, Wowk B, Pagotan R 167–75">{{cite journal|display-authors=etal|vauthors=Fahy GM, Wowk B, Pagotan R|date=July 2009|title=Physical and biological aspects of renal vitrification|journal=Organogenesis|volume=5|issue=3|pages=167–75|doi=10.4161/org.5.3.9974|pmc=2781097|pmid=20046680}}</ref><ref>{{cite journal|display-authors=etal|vauthors=Fahy GM, Wowk B, Wu J|date=April 2004|title=Cryopreservation of organs by vitrification: perspectives and recent advances|journal=Cryobiology|volume=48|issue=2|pages=157–78|doi=10.1016/j.cryobiol.2004.02.002|pmid=15094092}}</ref><ref>{{cite journal |last1=Fahy|first1=G|last2=Wowk|first2=B|last3=Wu|first3=J|last4=Phan|first4=J|last5=Rasch|first5=C|last6=Chang|first6=A|last7=Zendejas|first7=E|year=2005|title=Corrigendum to "Cryopreservation of organs by vitrification: perspectives and recent advances" |journal=Cryobiology |volume=50 |issue=3 |page=344|doi=10.1016/j.cryobiol.2005.03.002 |doi-access=}}</ref> This has allowed animal brains to be vitrified, thawed, and examined for ice damage using light and ]. No ice crystal damage was found;<ref name="lemler">{{cite journal |vauthors=Lemler J, Harris SB, Platt C, Huffman TM|date=June 2004|title=The arrest of biological time as a bridge to engineered negligible senescence |journal=Annals of the New York Academy of Sciences |volume=1019 |issue=1 |pages=559–563 |bibcode=2004NYASA1019..559L |pmid=15247086 |s2cid=27635898 |doi=10.1196/annals.1297.104}}</ref> cellular damage was due to dehydration and toxicity of the cryoprotectant solutions. | |||
Current solutions being used for ] are stable enough to avoid crystallization even when a vitrified ] is warmed up. This has recently allowed brains to be vitrified, warmed back up, and examined for ice damage using light and ]. No ice crystal damage was found.<ref>{{cite book | |||
| url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15247086 | |||
| publisher = Annals of New York Academy of Sciences | |||
| edition = 1019:559-63 | |||
| title = The arrest of biological time as a bridge to engineered negligible senescence | |||
| last = Lemler J, Harris SB, Platt C, Huffman TM | |||
| year = 2004 | |||
| accessdate = 2006-03-31}}</ref><ref>{{cite book | |||
| url = http://www.alcor.org/Library/html/annals.html | |||
| title = The Arrest of Biological Time as a Bridge to Engineered Negligible Senescence | |||
| last = Lemler J, Harris SB, Platt C, Huffman TM | |||
| publisher = Alcor Life Extension Foundation | |||
| year = 2004 | |||
| accessdate = 2006-03-31}}</ref><ref>{{cite book | |||
| url = http://www.alcor.org/Library/html/cambridge.html | |||
| title = Alcor Presentation at Cambridge University | |||
| last = Lemler J, Harris SB, Platt C, Huffman TM | |||
| publisher = Alcor Life Extension Foundation | |||
| year = 2004 | |||
| accessdate = 2006-03-31}}</ref> However, if the complete circulation of the protectant in the brain is compromised, protective chemicals may not be able to reach all parts of the brain, and ] may occur either during cooling or during rewarming. Cryonicists argue, however, that injury caused during cooling might, in the future, be repairable before the vitrified brain is warmed back up, and that damage during rewarming might be prevented by adding more ] in the solid state, or by improving rewarming methods. But even given the best vitrification that current technology allows, rewarming still does not allow revival, even if crystallization is avoided, due to the toxic effects of the cryoprotectants. Again, however, cryonicists counter that future technology might be able to overcome this difficulty, and find a way to combat the toxicity after rewarming. If, for example, the ] is due to ] ]s, those proteins could be repaired or replaced. | |||
Costs can include payment for medical personnel to be on call for death, vitrification, transportation in dry ice to a preservation facility, and payment into a trust fund intended to cover indefinite storage in liquid nitrogen and future revival costs.<ref name="independent chilling facts">{{cite news|title=Cryonics: the chilling facts|url=https://www.independent.co.uk/life-style/gadgets-and-tech/features/cryonics-the-chilling-facts-2326328.html|access-date=21 February 2016|work=]|date=26 July 2011|archive-date=14 June 2018|archive-url=https://web.archive.org/web/20180614171545/https://www.independent.co.uk/life-style/gadgets-and-tech/features/cryonics-the-chilling-facts-2326328.html|url-status=live}}</ref><ref name="nytimes dying hope">{{cite news|title=A Dying Young Woman's Hope in Cryonics and a Future|url=https://www.nytimes.com/2015/09/13/us/cancer-immortality-cryogenics.html|access-date=21 February 2016|work=]|date=12 September 2015|archive-date=2 August 2018|archive-url=https://web.archive.org/web/20180802161847/https://www.nytimes.com/2015/09/13/us/cancer-immortality-cryogenics.html|url-status=live}}</ref> As of 2011, U.S. cryopreservation costs can range from $28,000 to $200,000, and are often financed via life insurance.<ref name="independent chilling facts" /> ], which stores bodies communally in large ], charges $12,000 to $36,000 for the procedure.<ref name="ft" /> Some customers opt to have only their brain cryopreserved ("neuropreservation"), rather than their whole body. | |||
Some critics have speculated that because a cryonics patient has been declared ], their organs must be dead, and thus unable to allow ]s to reach the majority of cells. Cryonicists respond that it has been empirically demonstrated that, so long as the ] process begins immediately after legal death is declared, the individual organs (and perhaps even the patient as a whole) remain biologically alive; and vitrification (particularly of the brain) is quite feasible. This same principle is what allows organs, such as hearts, to be transplanted, even though they come from dead donors. | |||
As of 2014, about 250 corpses have been cryogenically preserved in the U.S., and around 1,500 people have signed up to have their remains preserved.<ref name="moen" /> As of 2016, there are four facilities that retain cryopreserved bodies, three in the U.S. and one in Russia.<ref name="guardian keep cool" /><ref>{{cite news|title='The ultimate lottery ticket:' Inside one of four cryonics facilities in the world|url=http://koin.com/2016/02/17/oregon-cryonics-the-ultimate-lottery-ticket/|access-date=21 February 2016|work=] (CBS Portland)|date=18 February 2016|archive-date=4 July 2017|archive-url=https://web.archive.org/web/20170704073553/http://koin.com/2016/02/17/oregon-cryonics-the-ultimate-lottery-ticket/|url-status=live}}</ref> | |||
Cryonics procedures cannot begin until legal pronouncement of ] has occurred, and pronouncement is usually based on cessation of ] (only very rarely on brain activity measurements). When the heart stops beating and ] flow ceases, ] damage begins. Deprived of ] and ], ]s, ]s and ]s begin to deteriorate. If the heart is restarted after too many minutes have passed, the reintroduced oxygen can cause even more damage due to ], a phenomenon known as ]. Cryonicists try to minimize ischemic and reperfusion injury by beginning cardio-pulmonary support (much like ]) and cooling as soon as possible after pronouncement of death. Anti-] agents like ] and ]s may be administered. Suspended Animation, Inc is a ] company that specializes in research into, and implementation of, optimal procedures for minimizing ] injury in cryonics rescue. | |||
A more recent development is Tomorrow Biostasis GmbH, a ]-based firm offering cryonics and standby and transportation services in ]. Founded in 2019 by Emil Kendziorra and Fernando Azevedo Pinheiro, it partners with the European Biostasis Foundation in ] for long-term corpse storage. The facility was completed in 2022.<ref>{{cite web |title=Tomorrow Biostasis |url=https://www.tomorrow.bio/ |access-date=26 December 2023 |archive-date=15 November 2023 |archive-url=https://web.archive.org/web/20231115144732/https://www.tomorrow.bio/ |url-status=live}}</ref><ref>{{cite news|title='Want to live longer? This Berlin startup aims to bring you back from the dead|url=https://tech.eu/2023/01/26/tomorrow-biostasis-wants-you-to-live-forever/|access-date=26 December 2023|work=tech.eu|date=26 January 2023|archive-date=11 August 2023|archive-url=https://web.archive.org/web/20230811023629/https://tech.eu/2023/01/26/tomorrow-biostasis-wants-you-to-live-forever/|url-status=live}}</ref> | |||
===Revival=== | |||
It is universally agreed by scientists and cryonics advocates that reversing human cryopreservation is not possible with “any near-term technology.”<ref>{{cite web | |||
| url = http://www.alcor.org/sciencefaq.htm | |||
| title = Scientists’ Cryonics FAQ | |||
| publisher = Alcor Life Extension Foundation | |||
| accessdate = 2006-04-03}}</ref> Those who believe that revival may someday be possible generally look toward advanced ], ], or ] as key technologies. Revival requires repairing damage from lack of oxygen, ] toxicity, thermal stress (fracturing), and freezing in tissues that do not successfully ]. In many cases extensive ] will be necessary. Hypothetical revival scenarios generally envision repairs being performed by vast numbers of microscopic organisms or devices.<ref>{{cite book | |||
| url = http://www.alcor.org/Library/html/MolecularRepairOfTheBrain.htm | |||
| accessdate = 2006-04-04 | |||
| title = Molecular Repair of the Brain | |||
| last = Merkle | |||
| first = R | |||
| publisher = Alcor Life Extension Foundation | |||
| year = 1994}}</ref><ref>{{cite book | |||
| url = http://www.alcor.org/Library/html/nanotechrepair.html | |||
| accessdate = 2006-04-04 | |||
| title = “Realistic” Scenario for Nanotechnological Repair of the Frozen Human Brain | |||
| publisher = Alcor Life Extension Foundation | |||
| year = 1991}}</ref><ref>{{cite book | |||
| url = http://www.foresight.org/EOC/EOC_Chapter_9.html#section03of06 | |||
| accessdate = 2006-04-04 | |||
| title = Engines of Creation | |||
| last = Drexler | |||
| first = E | |||
| publisher = Ancor Press/Doubleday | |||
| year = 1986}}</ref><ref>{{cite book | |||
| url = http://www.alcor.org/Library/html/resuscitation.htm | |||
| accessdate = 2006-04-04 | |||
| title = Resuscitation: A Speculative Scenario for Recovery | |||
| last = Darwin | |||
| first = M | |||
| publisher = Alcor Life Extension Foundation | |||
| year = 1988}}</ref> These devices would restore healthy cell structure and chemistry at the molecular level, ideally before warming. More radically, ] has also been suggested as a possible revival approach if and when technology is ever developed to scan the memory contents of a preserved brain. | |||
It seems extremely unlikely that any cryonics company could exist long enough to take advantage of the supposed benefits offered; historically, even the most robust corporations have only a one-in-a-thousand chance of lasting 100 years.<ref name=decline>{{cite journal |journal=Cogent Social Sciences |author=Stodolsky DS |title=The growth and decline of cryonics |doi=10.1080/23311886.2016.1167576 |volume=2 |year=2016 |issue=1 |page=1167576|doi-access=free}}</ref> Many cryonics companies have failed; {{asof|2018|lc=yes}}, all but one of the pre-1973 batch had gone out of business, and their stored corpses have been defrosted and disposed of.<ref name=hta-law>{{cite web |publisher=] |title=The law on cryonics |url=https://www.hta.gov.uk/law-cryonics |date=26 September 2018 |access-date=3 October 2019 |archive-date=30 September 2019 |archive-url=https://web.archive.org/web/20190930062900/https://www.hta.gov.uk/law-cryonics |url-status=live}}</ref> | |||
It has often been written that cryonics revival will be a last-in-first-out (]) process. In this view, preservation methods will get progressively better until eventually they are demonstrably reversible, after which medicine will begin to reach back and revive people cryopreserved by more primitive methods. Revival of people cryopreserved by the current combination of ] and deep-cooling (technically not "freezing", as cryoprotectant inhibits ice crystallization) may require centuries, if it is possible at all. | |||
==Obstacles to success== | |||
It has been claimed that if technologies for general molecular analysis and repair are ever developed, then theoretically any damaged body could be “revived.” Survival would then depend on whether preserved brain information was sufficient to permit restoration of all or part of the ] of the original person, with ] being the final dividing line between life and death. | |||
=== Preservation damage === | |||
Medical laboratories have long used cryopreservation to maintain animal cells, human embryos, and even some organized tissues, for periods as long as three decades.<ref>{{cite journal|vauthors=Crippen DW, Reis RJ, Risco R, Vita N|date=October 2015|title=The Science Surrounding Cryonics |url=https://www.technologyreview.com/2015/10/19/109714/the-science-surrounding-cryonics/|journal=MIT Technology Review}}</ref> But recovering large animals and organs from a frozen state is not considered possible now.<ref>{{cite journal|author=Smith Audrey U |year=1957 |title=Problems in the Resuscitation of Mammals from Body Temperatures Below 0 °C|journal=Proceedings of the Royal Society of London. Series B, Biological Sciences|volume=147|issue=929|pages=533–44|bibcode=1957RSPSB.147..533S|doi=10.1098/rspb.1957.0077|jstor=83173|pmid=13494469|s2cid=40568140}}</ref><ref name="Fahy GM, Wowk B, Pagotan R 167–75" /><ref>{{cite journal|vauthors=Fahy GM, Wowk B, Wu J|year=2006|title=Cryopreservation of complex systems: the missing link in the regenerative medicine supply chain|url=http://www.21cm.com/articles/Missing_Link.pdf|journal=Rejuvenation Research |volume=9 |issue=2 |pages=279–291 |citeseerx=10.1.1.539.7419|doi=10.1089/rej.2006.9.279|pmid=16706656|access-date=2017-10-24|archive-date=2017-10-25|archive-url=https://web.archive.org/web/20171025022108/http://www.21cm.com/articles/Missing_Link.pdf|url-status=live}}</ref> Large vitrified organs tend to develop fractures during cooling,<ref>{{cite journal |vauthors=Fahy GM, Saur J, Williams RJ |title=Physical problems with the vitrification of large biological systems|journal=Cryobiology |volume=27 |issue=5 |pages=492–510 |date=October 1990 |pmid=2249453 |doi=10.1016/0011-2240(90)90038-6}}</ref> a problem worsened by the large tissue masses and very low temperatures of cryonics.<ref>{{cite magazine |author=Wowk B |title=Systems for Intermediate Temperature Storage for Fracture Reduction and Avoidance| magazine =Cryonics| pages = 7–13| year=2011| volume =2011| issue =3| publisher = Alcor Life Extension Foundation| issn=1054-4305}}</ref> Without cryoprotectants, cell shrinkage and high salt concentrations during freezing usually prevent frozen cells from functioning again after thawing. Ice crystals can also disrupt connections between cells that are necessary for organs to function.<ref>{{cite journal|vauthors=Fahy GM, Levy DI, Ali SE|date=June 1987|title=Some Emerging Principles Underlying the Physical Properties, Biological Actions, and Utility of Vitrification Solutions|journal=Cryobiology|volume=24|issue=3|pages=196–213|doi=10.1016/0011-2240(87)90023-X|pmid=3595164}}</ref> | |||
Some cryonics organizations use vitrification without a ] step,<ref>{{cite web |title=Alcor Position Statement on Brain Preservation Prize |publisher=Alcor Life Extension Foundation |date=2016-02-12 |url=http://www.alcor.org/blog/alcor-position-statement-on-brain-preservation-foundation-prize/ |access-date=2016-03-20 |archive-date=2016-02-15 |archive-url=https://web.archive.org/web/20160215230517/http://www.alcor.org/blog/alcor-position-statement-on-brain-preservation-foundation-prize/ |url-status=live}}</ref> sacrificing some structural preservation quality for less damage at the molecular level. Some scientists, like João Pedro Magalhães, have questioned whether using a deadly chemical for fixation eliminates the possibility of biological revival, making chemical fixation unsuitable for cryonics.<ref>{{cite web |title=Mammal brain frozen and thawed out perfectly for first time |url=https://www.newscientist.com/article/2077140-mammal-brain-frozen-and-thawed-out-perfectly-for-first-time/ |access-date=2016-06-06 |work=] |archive-date=2016-06-16 |archive-url=https://web.archive.org/web/20160616185949/https://www.newscientist.com/article/2077140-mammal-brain-frozen-and-thawed-out-perfectly-for-first-time/ |url-status=live}}</ref> | |||
===Social obstacles=== | |||
Even if cryonics were scientifically certain to work, there are social obstacles that make success uncertain. The most obvious social obstacle is the prevailing belief that cryonics cannot work, and that cryonics subjects are dead. Although a legal determination of death by contemporary medicine is necessary to implement cryonics, this determination carries with it the implication of futility. By custom and law, dead bodies are objects, not persons with rights or protections. This removal of personhood is a cultural obstacle not faced by living people with even the poorest prognosis. For this reason, cryonics advocates call cryonics subjects “patients” and argue that morally they shouldn’t be considered dead, even though that is their status under present law. | |||
Outside of cryonics firms and cryonics-linked interest groups, many scientists are very skeptical about cryonics methods. ] Dayong Gao has said, "we simply don't know if been damaged to the point where they've 'died' during vitrification because the subjects are now inside liquid nitrogen canisters." Based on experience with organ transplants, biochemist Ken Storey argues that "even if you only wanted to preserve the brain, it has dozens of different areas which would need to be cryopreserved using different protocols".<ref name="bbc frozen" /> | |||
A related question is why future society would want to care for or revive “dead” people. Cryonicists note that a subset of society already cares for cryonics patients, and has done so for decades. It is assumed that should revival ever become possible, that same subset of society (the advocates who maintained patients long enough for revival to become possible) would pursue revival. They also believe that a future society with technology advanced enough to reverse cryopreservation would necessarily have views of life and death different from society today. They generally reject the idea that they are trying to "raise the dead", viewing cryonics instead as a highly experimental medical procedure. It has also been suggested that future society may have an interest in revival of cryonics patients for intellectual or historical value, although cryonicists tend to argue that healing and recovering sick people is an ethical imperative regardless of value to society at large. | |||
===Revival=== | |||
==Neuropreservation== | |||
Revival would require repairing damage from lack of oxygen, cryoprotectant toxicity, thermal stress (fracturing), and freezing in tissues that do not successfully vitrify, followed by reversing the cause of death. In many cases, extensive ] would be necessary.<ref>{{cite journal |last1=Karow |first1=Armand |last2=Webb |first2=Watts |title=Tissue Freezing: A theory for injury and survival |journal=Cryobiology |volume=2 |issue=3 |pages=99–108 |date=1965 |pmid=5860601 |doi=10.1016/s0011-2240(65)80094-3}}</ref> This revival technology remains speculative.<ref name="guardian cold facts" /> | |||
] is ] of the ], usually within the head, with surgical removal and disposal of the rest of the body. Neuropreservation, sometimes called “neuro,” is one of two distinct preservation options in cryonics, the other being "whole body" preservation. | |||
===Legal issues=== | |||
] is motivated by the fact that the ] is the primary repository of memory and ]. (For instance, spinal cord injury victims, organ transplant patients, and amputees appear to retain their ].) It is also motivated by the belief that reversing any type of cryonic preservation is so difficult and complex that any future technology capable of it must by its nature be capable of generalized ], including regrowth of a new body around a repaired brain. Some suggested revival scenarios for whole body patients even involve discarding the original body and regenerating a new one because tissues are so badly damaged by the preservation process. These considerations, along with lower costs, easier transportation in emergencies, and the specific focus on brain preservation quality, have motivated many cryonicists to choose ]. | |||
Historically, people had little control over how their bodies were treated after death, as religion held jurisdiction over the matter.<ref name="trust">{{cite book |last1=Dukeminier |first1=Jesse |last2=Sitkoff |first2=Robert |date=2013 |title=Wills, Trusts, and Estates |publisher=Wolters Kluwer Law & Business in New York |page=507 |isbn=978-1-4548-2457-2}}</ref> But secular courts began to exercise jurisdiction over corpses and use discretion in carrying out deceased people's wishes.<ref name="trust" /> Most countries legally treat preserved bodies as ] persons because of laws that forbid vitrifying someone who is medically alive.<ref name="guardian frozen in time">{{cite web|url=https://www.theguardian.com/technology/2008/feb/14/research.cryonics|title=Patients who are frozen in time|website=]|date=14 February 2008|access-date=12 October 2020|archive-date=12 May 2019|archive-url=https://web.archive.org/web/20190512202813/https://www.theguardian.com/technology/2008/feb/14/research.cryonics|url-status=live}}</ref> In France, cryonics is not considered a legal mode of body disposal;<ref>{{cite web |url=http://www.leparticulier.fr/jcms/c_101664/conseil-d-etat-du-06/01/2006-n-260307-cryogenisation-interdiction |title=Conseil d'État du 06/01/2006, n° 260307: Cryogénisation – interdiction |access-date=2014-01-07 |archive-url=https://web.archive.org/web/20140107144511/http://www.leparticulier.fr/jcms/c_101664/conseil-d-etat-du-06/01/2006-n-260307-cryogenisation-interdiction |archive-date=2014-01-07 |url-status=dead}}</ref> only burial, cremation, and formal ] to science are allowed, though bodies may legally be shipped to other countries for cryonic freezing.<ref>{{cite news|last=Chrisafis|first=Angelique|title=Freezer failure ends couple's hopes of life after death|url=https://www.theguardian.com/science/2006/mar/17/france.internationalnews|access-date=8 January 2014|newspaper=]|date=16 March 2006|archive-date=8 January 2014|archive-url=https://web.archive.org/web/20140108035430/http://www.theguardian.com/science/2006/mar/17/france.internationalnews |url-status=live}}</ref> As of 2015, ] prohibits the sale of arrangements for cryonic body preservation.<ref>{{cite news|last=Proctor|first=Jason|title=Immortality sought through B.C. Supreme Court lawsuit|url=http://www.cbc.ca/news/canada/british-columbia/immortality-sought-through-b-c-supreme-court-lawsuit-1.3153430|access-date=21 February 2016|publisher=]|date=16 July 2015|archive-date=21 February 2016|archive-url=https://web.archive.org/web/20160221125254/http://www.cbc.ca/news/canada/british-columbia/immortality-sought-through-b-c-supreme-court-lawsuit-1.3153430|url-status=live}}</ref> In Russia, cryonics falls outside both the medical industry and the funeral services industry, making it easier than in the U.S. to get hospitals and morgues to release cryonics candidates.<ref name="ft" /> | |||
In 2016, the English ] ruled in favor of a mother's right to seek cryopreservation of her terminally ill 14-year-old daughter, as the girl wanted, contrary to the father's wishes. The decision was made on the basis that the case represented a conventional dispute over the disposal of the girl's body, although the judge urged ministers to seek "proper regulation" for the future of cryonic preservation after the hospital raised concerns about the competence and professionalism of the team that conducted the preservation procedures.<ref>{{cite news |url=https://www.bbc.co.uk/news/health-38012267 |title=Terminally ill teen won historic ruling to preserve body |date=18 November 2016 |publisher=] |language=en-GB |access-date=18 November 2016 |archive-date=18 November 2016 |archive-url=https://web.archive.org/web/20161118012553/http://www.bbc.co.uk/news/health-38012267|url-status=live}}</ref> In ''] v. Richardson'', the ] ordered the disinterment of Richardson, who was buried against his wishes, for cryopreservation.<ref name="trust" /><ref>{{cite web |title=Alcor Life Extension Foundation v. Richardson |url=http://www.leagle.com/decision/In%20IACO%2020100512306/ALCOR%20LIFE%20EXTENSION%20FOUND.%20v.%20RICHARDSON |date=2010 |publisher=785 N.W.2d 717 |access-date=2017-01-07 |archive-date=2017-01-07 |archive-url=https://web.archive.org/web/20170107171724/http://www.leagle.com/decision/In%20IACO%2020100512306/ALCOR%20LIFE%20EXTENSION%20FOUND.%20v.%20RICHARDSON |url-status=live}}</ref> | |||
The advantages and disadvantages of ] are often debated among cryonics advocates. Critics of ] note that the body is a record of much life experience, including learned motor skills. While few cryonicists doubt that a revived neuro patient would be the same person, there are wider questions about how a regenerated body might feel different from the original.<ref>{{cite book | |||
| url = http://www.alcor.org/Library/html/CaseForWholeBody.html | |||
| last = O'Neal | |||
| first = Michael B. | |||
| year = 1990 | |||
| work = Cryonics | |||
| title = The Case for Whole Body Suspension | |||
| publisher = Alcor Life Extension Foundation | |||
| accessdate = 2006-03-16}}</ref> Partly for these reasons (as well as for better public relations), the ] preserves only whole bodies. Some proponents of ] agree with these concerns, but still feel that lower costs and better brain preservation justify preserving only the brain. About three-quarters of the patients stored at ] are "neuros". | |||
A detailed legal examination by Jochen Taupitz concludes that cryonic storage is legal in Germany for an indefinite period.<ref>{{cite book |last1=Taupitz |first1=Jochen |last2=Fuhr |first2=Günther |last3=Zwick |first3=Anna |last4=Salkic |first4=Amina |date=2013 |title=Unterbrochenes Leben? |url=https://www.bookshop.fraunhofer.de/buch/unterbrochenes-leben/240032 |location=St. Ingbert, Germany |publisher=Fraunhofer Verlag |isbn=978-3-8396-0593-6 |access-date=2018-12-26 |archive-date=2018-12-27 |archive-url=https://web.archive.org/web/20181227040823/https://www.bookshop.fraunhofer.de/buch/unterbrochenes-leben/240032 |url-status=live}}</ref> | |||
Although media sometimes report that ] is expected to regrow new bodies, cryonics experts generally dismiss cloning as a primitive technology that will be long obsolete before any kind of revival becomes possible. Similarly, although neurosurgeon ] proved<ref>{{cite web | |||
| url = http://www.langues-vivantes.u-bordeaux2.fr/Interactive/P2/transplant2r.htm | |||
| last = White | |||
| first = Robert J. | |||
| title =Head Transplants | |||
| accessdate = 2006-03-18}}</ref> | |||
that body transplants were possible in primates, transplantation is dismissed in favor of tissue regeneration as the preferred method for treating ] and other trauma in future medicine. | |||
==Ethics== | |||
==Financial issues== | |||
Writing in '']'' in 2009, David Shaw examined cryonics. The arguments he cited against it included changing the concept of death, the expense of preservation and revival, lack of scientific advancement to permit revival, temptation to use premature euthanasia, and failure due to catastrophe. Arguments in favor of cryonics include the potential benefit to society, the prospect of immortality, and the benefits associated with avoiding death. Shaw explores the expense and the potential payoff, and applies an adapted version of ] to the question.<ref name="shaw cryoethics">Shaw, David. "Cryoethics: seeking life after death", '']'' 23.9 (2009): 515–521. APA</ref>{{dubious|date=August 2024}} | |||
Costs of cryonics vary greatly, ranging from $9,000 for ] by ], to $28,000 for whole body cryopreservation by the ], to $150,000 for whole body cryopreservation by ] or the ]. To some extent these cost differences reflect differences in how fees are quoted. The ] fee doesn’t include “standby” (a team that begins procedures at bedside), transportation costs, or funeral director expenses outside of Michigan, which must be purchased as extras. CI Members wanting Standby and Transport from cryonics professionals can contract for additional payment to the ]-based company Suspended Animation, Inc. | |||
In 2016, Charles Tandy wrote in support of cryonics, arguing that honoring someone's ] is seen as a benevolent duty in American and many other cultures.<ref>{{cite SSRN|title=An Open Letter to Physicians in Death-with-Dignity States (The Case of a Terminally Ill Cryonicist)|last=Tandy|first=Charles|date=8 February 2017|ssrn=2913107}}</ref> | |||
While cryonics is sometimes suspected of being greatly profitable, the high expenses of doing cryonics are well documented.<ref>{{cite book | |||
| url = http://www.alcor.org/Library/html/CostOfCryonics.html | |||
| title = The Cost of Cryonics | |||
| last = Darwin | |||
| first = Mike | |||
| publisher = Alcor Life Extension Foundation | |||
| work = Cryonics | |||
| year = 1990 | |||
| accessdate = 2006-03-17}}</ref> The expenses are comparable to major transplant surgeries. The largest single expense, especially for whole body cases, is the money that must be set aside to generate interest to pay for maintenance in perpetuity. | |||
The most common method of paying for cryonics is ], which spreads the cost over many years. Cryonics advocates are quick to point out that such insurance is especially affordable for young people. It has been claimed that cryonics is “affordable for the vast majority” of people in the industrialized world who really want it and plan for it in advance. | |||
==Philosophical and ethical considerations== | |||
Cryonics is based on a view of dying as a process that can be stopped in the minutes, and perhaps hours, following ]. If ] is not an event that happens suddenly when the heart stops, this raises philosophical questions about what exactly death is. In 2005 an ethics debate in the medical journal, Critical Care, noted “…few if any patients pronounced dead by today’s physicians are in fact truly dead by any scientifically rigorous criteria.”<ref>{{cite book | |||
| url = http://ccforum.com/inpress/cc3894/abstract | |||
| publisher = Critical Care Forum | |||
| title = Pro/con ethics debate: When is dead really dead? | |||
| year = ] | |||
| last = Whetstine | |||
| first = Leslie | |||
| coauthors = Stephen Streat, Mike Darwin, and David Crippen | |||
| accessdate = 2006-03-17}}</ref> Cryonics proponent ] has argued that “death” based on ] or resuscitation failure is a purely social construction used to justify terminating care of dying patients.<ref>{{cite book | |||
| url = http://www.alcor.org/Library/html/ProspectsOfACureForDeath.html | |||
| title = Prospects of a Cure for "Death" | |||
| work = Cryonics | |||
| year = 1990 | |||
| last = Donaldson | |||
| first = Thomas | |||
| publisher = Alcor Life Extension Foundation | |||
| accessdate = 2006-03-17}}</ref> In this view, ] and its aftermath are a form of ] in which sick people are abandoned. Philosopher ] suggested a distinction between death associated with circumstances and intention versus death that is absolutely irreversible.<ref>{{cite book | |||
| url = http://www.alcor.org/Library/html/TerminusOfTheSelf.html | |||
| title = The Terminus of the Self | |||
| work = Cryonics | |||
| year = 1995 | |||
| last = More | |||
| first = Max | |||
| accessdate = 2006-03-17 | |||
| publisher = Alcor Life Extension Foundation}}</ref> Absolutely irreversible death has also been called ], which is destruction of the brain to such an extent that the original information content can no longer be inferred. ] ] has written that increasing rights will accrue to cryonics patients as prospects for revival become clearer, noting that recovery of legally dead persons has precedent in the discovery of missing persons.<ref>{{cite book | |||
| url = http://www.jetpress.org/volume6/death.htm | |||
| accessdate = 2006-03-17 | |||
| title = The Future of Death: Cryonics and the Telos of Liberal Individualism | |||
| last = Hughes | |||
| first = James J. | |||
| work = Journal of Evolution and Technology | |||
| edition = Volume 6 | |||
| year = 2001 | |||
| publisher = Jet Press}}</ref> | |||
] and ] opinions of cryonics tend to pivot on the issue of whether cryonics is regarded as ] or ]. If cryonics is interment, then ] beliefs about death and ] may come into consideration. Resuscitation may be deemed impossible by those with religious beliefs because the ] is gone, and according to most religions only ] can ] the dead. Expensive interment is seen as a waste of resources. If cryonics is regarded as medicine, with ] as a mere enabling mechanism, then cryonics is a long-term ] with uncertain prognosis. It is continuing to care for sick people when others have given up, and a legitimate use of resources to sustain human life. Cryonics advocates complain that theological dismissal of cryonics because it is interment is a circular argument because calling cryonics "interment" presumes that cryonics cannot work.<ref>{{cite web | |||
| url = http://www.alcor.org/Library/html/hesdeadjim.htm | |||
| title = He's Dead, Jim, The Irreversibility of Death as a Circular Argument | |||
| publisher = Alcor Life Extension Foundation | |||
| accessdate = 2006-03-17}}</ref> They believe future technical advances will validate their view that cryonics patients are recoverable, and therefore never really dead.. | |||
] has published a vigorous Christian defense of cryonics,<ref>{{cite web | |||
| url = http://www.alcor.org/Library/html/christianityandcryonics.html | |||
| title = Christianity and Cryonics | |||
| publisher = Alcor Life Extension Foundation | |||
| accessdate = 2006-03-17}}</ref> including excerpts of a sermon by ] Reverend Kay Glaesner. Noted ] apologist ] has defended cryonics.<ref>{{cite book | |||
| url = http://www.alcor.org/Library/html/cryonicsandorthodoxy.html | |||
| publisher = Christianity Today | |||
| edition = 12, 816 | |||
| title = Cryonics and Orthodoxy | |||
| last = Montgomery | |||
| first = John Warwick | |||
| year = ] | |||
| accessdate = 2006-03-17}}</ref> In 1969, a ] priest ] the cryonics capsule of Ann DeBlasio, one of the first cryonics patients<ref>{{cite journal | author=] | title=Cryonic Suspension of Ann DeBlasio | journal=CRYONICS REPORTS | volume=4 | issue=9-10 | publisher=Cryonics Society of New York, Inc. | |||
| date=Sep-Oct 1969 | pages=10-15}}</ref>. In 2002, a ] cleric indicated in a media interview that cryonics would be compatible with ] if it were medicine.{{Fact|date=February 2007}} Many followers of ] see cryonics as an important step in the Common Cause project (reference: Fedorov seminar in Moscow, Russia on 25.11.2006) and compatible with ]. | |||
==History== | ==History== | ||
{{See also|Cryopreservation#History|Embryo cryopreservation}} | |||
] suggested in a famous 1773 letter<ref>{{cite book | |||
| url = http://www.foresight.org/EOC/EOC_Chapter_9.html | |||
| publisher = Foresight Nanotech Institute | |||
| title = Letter to Jacques Duborg | |||
| last = Franklin | |||
| first = Benjamin | |||
| year = 1773 | |||
| accessdate = 2006-03-17}}</ref> that it might be possible to preserve human life in a suspended state for centuries. However, the modern era of cryonics began in 1962 when Michigan college physics teacher ] proposed in a privately published book, “The Prospect of Immortality”,<ref>{{cite book | first= Robert C.W. | last= Ettinger| year= 1964 | title= The Prospect of Immortality| edition= First | publisher= Doubleday|url = http://www.cryonics.org/book1.html}}</ref> that freezing people may be a way to reach future medical technology. Even though freezing a person is apparently fatal, Ettinger argued that what appears to be fatal today may be reversible in the future. He applied the same argument to the process of dying itself, saying that the early stages of ] may be reversible in the future. Combining these two ideas, he suggested that freezing recently deceased people may be a way to save lives. | |||
Cryopreservation was applied to human cells beginning in 1954 with frozen sperm, which was thawed and used to inseminate three women.<ref>{{cite news|title=Fatherhood After Death Has Now Been Proved Possible|newspaper=Cedar Rapids Gazette|date=April 9, 1954}}</ref> The freezing of humans was first scientifically proposed by Michigan professor ] in ''The Prospect of Immortality'' (1962).<ref name=dilemma>{{cite web|url=https://www.theguardian.com/science/2016/nov/18/the-cryonics-dilemma-will-deep-frozen-bodies-be-fit-for-new-life|title=The cryonics dilemma: will deep-frozen bodies be fit for new life?|website=]|last=Devlin|first=Hannah|date=November 18, 2016|access-date=September 22, 2018|archive-date=September 23, 2018|archive-url=https://web.archive.org/web/20180923052213/https://www.theguardian.com/science/2016/nov/18/the-cryonics-dilemma-will-deep-frozen-bodies-be-fit-for-new-life|url-status=live}}</ref> In 1966, the first human body was frozen—though it had been embalmed for two months—by being placed in ] and stored at just above freezing. The middle-aged woman from Los Angeles, whose name is unknown, was soon thawed and buried by relatives.<ref name=alcor>{{cite web|url=https://alcor.org/Library/html/suspensionfailures.html|title=Suspension Failures – Lessons from the Early Days|last=Perry|first=R. Michael|website=ALCOR: Life Extension Foundation|date=October 2014|access-date=August 29, 2018|archive-date=April 16, 2020|archive-url=https://web.archive.org/web/20200416155826/https://alcor.org/Library/html/suspensionfailures.html|url-status=live}}</ref> | |||
Slightly before ] book was complete, Evan Cooper<ref>{{cite web | |||
| url = http://www.cryonet.org/cgi-bin/dsp.cgi?msg=23124 | |||
| title = Ev Cooper | |||
| accessdate = 2006-03-17}}</ref> (writing as Nathan Duhring) privately published a book called “Immortality: Physically, Scientifically, Now” that independently suggested the same idea. Cooper founded the Life Extension Society in 1965 to promote freezing people. ] came to be credited as the originator of cryonics, perhaps because his book was republished by Doubleday in 1964 on recommendation of ] and ], and received more publicity. Ettinger also stayed with the movement longer. Nevertheless, cryonics historian R. Michael Perry has written “Evan Cooper deserves the principal credit for forming an organized cryonics movement.”<ref>{{cite web | |||
| url = http://www.alcor.org/cryonics/cryonics9208.txt | |||
| title = Cryonics | |||
| accessdate = 2006-03-17}}</ref> | |||
The first body to be cryopreserved and then frozen in hope of future revival was that of ]. ]'s ] says Bedford's body was cryopreserved around two hours after his death by cardiorespiratory arrest (secondary to metastasized kidney cancer) on January 12, 1967.<ref>{{cite web |title=Dear Dr. Bedford (and those who will care for you after I do) |publisher=Cryonics |date=July 1991 |url=http://www.alcor.org/Library/html/BedfordLetter.htm |first1=Mike |last1=Darwin |access-date=2009-08-23 |archive-date=2020-03-16 |archive-url=https://web.archive.org/web/20200316200916/https://www.alcor.org/Library/html/BedfordLetter.htm |url-status=live}}</ref> Bedford's corpse is the only one frozen before 1974 still preserved today.<ref name=alcor/> In 1976, Ettinger founded the ]; his corpse was cryopreserved in 2011.<ref name=dilemma/> In 1981, Robert Nelson, "a former TV repairman with no scientific background" who led the Cryonics Society of California, was sued for allowing nine bodies to thaw and decompose in the 1970s; in his defense, he claimed that the Cryonics Society had run out of money.<ref name=alcor/> This lowered the reputation of cryonics in the U.S.<ref name=ft>{{cite news|title=Inside the weird world of cryonics|url=http://www.ft.com/intl/cms/s/2/d634e198-a435-11e5-873f-68411a84f346.html|access-date=21 February 2016|work=]|date=18 December 2015|archive-date=8 September 2016|archive-url=https://web.archive.org/web/20160908025414/http://www.ft.com/intl/cms/s/2/d634e198-a435-11e5-873f-68411a84f346.html|url-status=live}}</ref> | |||
The actual word “cryonics” was invented by Karl Werner in 1965 in conjunction with the founding of the Cryonics Society of New York (CSNY) by ] and ] that same year. This was followed by the founding of the Cryonics Society of Michigan (CSM) and Cryonics Society of California (CSC) in 1966, and Bay Area Cryonics Society (BACS) in 1969 (renamed the ], or ACS, in 1985). CSM eventually became the Immortalist Society, a non-profit affiliate of the ] (CI), a cryonics service organization founded by ] in 1976, now the second-largest cryonics organization. | |||
In 2018, a ] startup called Nectome was recognized for developing a method of preserving brains with chemicals rather than by freezing. The method is fatal, performed as euthanasia under general anesthesia, but the hope is that future technology will allow the brain to be physically scanned into a computer simulation, neuron by neuron.<ref>{{cite magazine |url=https://www.technologyreview.com/s/610456/a-startup-is-pitching-a-mind-uploading-service-that-is-100-percent-fatal/ |title=A startup is pitching a mind-uploading service that is "100 percent fatal" |date=13 March 2018 |magazine=MIT Technology Review |first1=Antonio |last1=Regalado |access-date=22 March 2018 |archive-date=23 January 2021 |archive-url=https://web.archive.org/web/20210123132955/https://www.technologyreview.com/2018/03/13/144721/a-startup-is-pitching-a-mind-uploading-service-that-is-100-percent-fatal/ |url-status=live}}</ref> | |||
Although there was at least one earlier aborted case, it is generally accepted that the first person frozen with intent of future resuscitation was ], a 73-year-old psychology professor frozen under crude conditions by CSC on ], ]. The case made the cover of a limited print run of ] before the presses were stopped to report the death of three astronauts in the ] fire instead. | |||
==Demographics== | |||
Cryonics suffered a major setback in 1979 when it was discovered that nine bodies stored by CSC in a cemetery in Chatsworth, California, thawed due to depletion of funds.<ref>{{cite book | |||
According to '']'', cryonicists are predominantly non-religious white men, outnumbering women by about three to one.<ref name="nytimes do us part">{{cite news|last=Howley|first=Kerry|title=Until Cryonics Do Us Part|url=https://www.nytimes.com/2010/07/11/magazine/11cryonics-t.html |url-access=subscription |access-date=2 February 2016|work=]|date=7 July 2010|archive-date=16 May 2016|archive-url=https://web.archive.org/web/20160516053504/http://www.nytimes.com/2010/07/11/magazine/11cryonics-t.html|url-status=live}}</ref> According to '']'', as of 2008, while most cryonicists used to be young, male, and "geeky", recent demographics have shifted slightly toward whole families.<ref name="guardian frozen in time" /> | |||
| url = http://www.alcor.org/Library/html/suspensionfailures.html | |||
| last = Perry | |||
| first = R. Michael | |||
| work = Cryonics | |||
| year = 1992 | |||
| publisher = Alcor Life Extension Foundation | |||
| accessdate = 2006-03-17 | |||
| title = Suspension Failures: Lessons from the Early Years}}</ref> Some of the bodies had apparently thawed years earlier without notification. The head of CSC was sued, and negative publicity slowed cryonics growth for years afterward. Of seventeen documented cryonics cases between 1967 and 1973, only James Bedford remains ] today. Strict financial controls and requirements adopted in response to the Chatsworth scandal have resulted in the successful maintenance of almost all cryonics cases since that era. | |||
In 2015, Du Hong, a 61-year-old female writer of children's literature, became the first known Chinese national to have her head cryopreserved.<ref>{{cite web |author=Stephen Chen |url=http://www.scmp.com/tech/science-research/article/1859328/cheating-death-elderly-writer-first-known-chinese-test-subject |title=Cheating death? Elderly writer is the first known Chinese to embrace cryogenics, her head now frozen by lab in Arizona |publisher=South China Morning Post |url-access=subscription |date=2015-09-18 |access-date=2015-09-24 |archive-date=2015-09-20 |archive-url=https://web.archive.org/web/20150920225245/http://www.scmp.com/tech/science-research/article/1859328/cheating-death-elderly-writer-first-known-chinese-test-subject |url-status=live}}</ref> | |||
The largest cryonics organization today was established by ] in 1972 as the Alcor Society for Solid State Hypothermia (ALCOR). In 1977 the name was changed to the ]. In 1982, the Institute for Advanced Biological Studies (IABS) founded by ] and Steve Bridge in Indiana merged with Alcor. By combining ] technical and communications skills with those of medical scientist ], this merger is generally regarded as a key event that allowed Alcor to attract a critical mass of knowledgeable people, eventually moving Alcor to a leading position in the field. | |||
==Reception== | |||
During the 1980s Darwin worked with ] cardiothoracic surgery researcher ] at ] to develop a medical model for cryonics procedures. Prior to ] and ], cryonics preparation was little more than a mortuary procedure in which ] chemicals were substituted for embalming fluid. ] and ] showed that ] and medications applied immediately after ], followed by cardiopulmonary bypass and thoracic surgery for access to major blood vessels, could greatly reduce ] injury (injury caused by stopped blood flow) in cryonics patients. They pioneered the cryonics procedure now known as a “standby”, in which a stabilization team stands by to institute life support procedures at the bedside of a cryonics patient as soon as possible after the heart stops. While supporting blood circulation and oxygenation of cryonics patients was first proposed by ], and the Cryonics Society of Michigan had a ] for this purpose as early as the late 1960s, the first consistent documented use of such procedures was in the 1980s. | |||
Cryonics is generally regarded as a fringe pseudoscience.<ref name=jk>{{cite news |title=Mainstream science is frosty over keeping the dead on ice |author=Steinbeck RL |newspaper=] |date=29 September 2002 |url=https://www.chicagotribune.com/news/ct-xpm-2002-09-29-0209290429-story.html |access-date=2019-07-17 |archive-date=2019-07-17 |archive-url=https://web.archive.org/web/20190717153237/https://www.chicagotribune.com/news/ct-xpm-2002-09-29-0209290429-story.html |url-status=live}}</ref> Between 1982<ref>{{cite magazine|magazine=Cryonics|date=November 1982|author=Jerry D. Leaf|access-date=2024-12-03|title=Cryo-82, The Big Freeze|pages=5–11,24|publisher= Alcor Life Extension Foundation|url=https://www.cryonicsarchive.org/docs/cryonics-magazine-1982-11.pdf|url-status=live|quote=There are other members of the Society for Cryobiology that are involved in cryonics, but have been told they would be excluded from their chosen profession, cryobiology, if this became public knowledge.}}</ref> and November 2018, the ] rejected members who practiced cryonics,<ref name="2022-mit-dream">{{cite web|date=2022-10-14|access-date=2024-12-03|website=MIT Technology Review|title=Why the sci-fi dream of cryonics never died|url=https://www.technologyreview.com/2022/10/14/1060951/cryonics-sci-fi-freezing-bodies|last=Clarke|first=Laurie|url-status=live|quote=The Society for Cryobiology has even dropped its past cryonics-related restrictions.|archive-url=https://web.archive.org/web/20221014210354/https://www.technologyreview.com/2022/10/14/1060951/cryonics-sci-fi-freezing-bodies/|archive-date=2022-10-14}}</ref><ref name="2018-statement" /> and issued a public statement saying that cryonics "is an act of speculation or hope, not science", and as such outside the scope of the Society.<ref name="2018-statement">{{cite web |url=https://www.societyforcryobiology.org/assets/documents/Position_Statement_Cryonics_Nov_18.pdf |title=Position Statement - Cryonics |website=Society for Cryobiology |date=November 2018 |access-date=2019-07-18 |archive-date=2019-04-01 |archive-url=https://web.archive.org/web/20190401172118/https://www.societyforcryobiology.org/assets/documents/Position_Statement_Cryonics_Nov_18.pdf |url-status=live|quote=The Society recognizes and respects the freedom of individuals to hold and express their own opinions and to act, within lawful limits, according to their beliefs. Preferences regarding disposition of postmortem human bodies or brains are clearly a matter of personal choice and, therefore, inappropriate subjects of Society policy. The Society does, however, take the position that the knowledge necessary for the revival of live or dead whole mammals following cryopreservation does not currently exist and can come only from conscientious and patient research in cryobiology and medicine. In short, the act of preserving a body, head or brain after clinical death and storing it indefinitely on the chance that some future generation may restore it to life is an act of speculation or hope, not science, and as such is outside the purview of the Society for Cryobiology.}}</ref> | |||
Russian company ] is the first non-U.S. vendor of cryonics services. Yevgeny Alexandrov, chair of the ] commission against pseudoscience, said there was "no scientific basis" for cryonics, and that the company was based on "unfounded speculation".<ref name=rus>{{cite news |newspaper=Daily Telegraph |title='Insurance' against death: Russian cryonics firm plans Swiss lab for people in pursuit of eternal life |first=Alex |last=Luhn |date=11 November 2017 |url=https://www.telegraph.co.uk/news/2017/11/11/insurance-against-death-russian-cryonics-firm-plans-swiss |url-access=subscription |access-date=28 July 2019 |archive-date=28 July 2019 |archive-url=https://web.archive.org/web/20190728135525/https://www.telegraph.co.uk/news/2017/11/11/insurance-against-death-russian-cryonics-firm-plans-swiss/ |url-status=live}}</ref> | |||
Cryonics received new support in the 1980s when MIT engineer ] started publishing papers and books foreseeing the new field of ]. His 1986 book, ], included an entire chapter on cryonics applications.<ref name="Note7">{{cite book | |||
| url = http://www.foresight.org/EOC/EOC_Chapter_9.html | |||
| title = Engines of Creation, "A Door to the Future" | |||
| year = 1986 | |||
| last = Drexler | |||
| first = K. Eric | |||
| publisher = Foresight Nanotech Institute | |||
| accessdate = 2006-03-17}}</ref> Cryonics advocates saw the nascent field of nanotechnology as vindication of their long held view that molecular repair of injured tissue was theoretically possible.<ref>{{cite book | |||
| last = Drexler | |||
| first = K. Eric | |||
| url = http://www.foresight.org/EOC/EOC_References.html#0156 | |||
| title = Engines of Creation, The Coming Age of Nanotechnology | |||
| publisher = Foresight Nanotech Institute | |||
| year = 1986 | |||
| accessdate = 2006-03-17}}</ref> | |||
Scientists have expressed skepticism about cryonics in media sources,<ref name="ft" /> and the Norwegian philosopher ] has written that the topic receives a "minuscule" amount of attention in academia.<ref name=moen/> | |||
Nanotechnology has also been the cause of controversy within the cryonics field, with some cryonics advocates arguing that sophisticated preservation methods aren’t necessary because “nanotechnology is necessary and sufficient” for cryonics to work. Critics countered that believing nanotechnology is necessary and sufficient without regard to preservation quality is more religion than science. The simultaneous advent of ] and ] medical model of cryonics, and the nanotechnology repair paradigm, polarized cryonics into two schools of thought that persist to the present day.<ref>{{cite web | |||
| url = http://www.alcor.org/Library/html/MythOfTheGoldenScalpel.html | |||
| last = Darwin | |||
| first = Mike | |||
| work = Cryonics | |||
| year = 1986 | |||
| publisher = Alcor Life Extension Foundation | |||
| title = The Myth of the Golden Scalpel | |||
| accessdate = 2006-03-17}}</ref> One school tends to believe that simple inexpensive procedures administered by morticians are sufficient, while the other advocates monitoring and maintaining viability by contemporary medical methods as far as possible into the procedure, with reversible ] as an ultimate goal. | |||
While some neuroscientists contend that all the subtleties of a human mind are contained in its anatomical structure,<ref>{{cite news|author1=Jerry Adler|title=The Quest to Upload Your Mind into the Digital Space|url=http://www.smithsonianmag.com/innovation/quest-upload-mind-into-digital-space-180954946/|access-date=21 February 2016|work=]|date=May 2015|archive-date=3 March 2016|archive-url=https://web.archive.org/web/20160303055411/http://www.smithsonianmag.com/innovation/quest-upload-mind-into-digital-space-180954946/|url-status=live}}</ref> few will comment directly on cryonics due to its speculative nature. People who intend to be frozen are often "looked at as a bunch of kooks".<ref>{{cite news|title=Brain Freeze: Can putting faith in cryonics deliver life after death?|url=http://www.torontosun.com/2015/10/06/brain-freeze-can-putting-faith-in-cryonics-deliver-life-after-death|newspaper=]|access-date=21 February 2016|date=6 October 2015|archive-date=12 March 2016|archive-url=https://web.archive.org/web/20160312064530/http://www.torontosun.com/2015/10/06/brain-freeze-can-putting-faith-in-cryonics-deliver-life-after-death|url-status=live}}</ref> Cryobiologist ] said in 2004 that cryonics is impossible and will never be possible, as cryonics proponents are proposing to "overturn the laws of physics, chemistry, and molecular science".<ref name=popsicle>{{cite journal |author=Miller K |title=Cryonics redux: is vitrification a viable alternative to immortality as a popsicle? |journal=Skeptic |volume=11 |issue=1 |year=2004 |page=24}}</ref> Neurobiologist Michael Hendricks has said, "Reanimation or simulation is an abjectly false hope that is beyond the promise of technology and is certainly impossible with the frozen, dead tissue offered by the 'cryonics' industry".<ref name=ft/> | |||
In the late 1980s a nexus of favorable circumstances, including technical progress, support from nanotechnology experts, and effective communications, led to a period of rapid growth, especially of ]. ] membership expanded tenfold within a decade, with a 30% annual growth rate between 1988 and 1992. | |||
Anthropologist ] writes that cryonics is a typical pseudoscience because of its lack of ] and testability. In his view, cryonics is not science, but religion: it places faith in nonexistent technology and promises to overcome death.<ref name=sd>{{cite journal |title=Cryonics: Science or Religion |vauthors=Dein S |journal=Journal of Religion & Health |year=2022 |volume=61 |issue=4 |pages=3164–3176 |pmid=33523374 |s2cid=231745500 |doi=10.1007/s10943-020-01166-6}}</ref> | |||
] was disrupted by political turmoil in 1993 when a group of activists left to start the CryoCare Foundation,<ref>{{cite web | |||
| url = http://www.cryocare.org/index.cgi | |||
| title = CryoCare Foundation | |||
| accessdate = 2006-03-17}}</ref> and associated for-profit companies CryoSpan, Inc. (headed by Paul Wakfer) and BioPreservation, Inc.<ref>{{cite web | |||
| url = http://www.cryocare.org/index.cgi?subdir=bpi&url=bpi.html | |||
| accessdate = 2006-03-17 | |||
| title = BioPreservation, Inc. - Cryopreservation Services}}</ref> (headed by ]). ] and collaborators made many technical advances during this time period, including a landmark study documenting high quality brain preservation by freezing with high concentrations of glycerol.<ref>{{cite web | |||
| url = http://www.alcor.org/Library/html/braincryopreservation1.html | |||
| title = Effect of Human Cryopreservation Protocol on the Ultrastructure of the Canine Brain | |||
| last = Platt | |||
| first = Charles | |||
| publisher = Alcor Life Extension Foundation | |||
| work = Cryocare | |||
| edition = Report #4 | |||
| year = 1995 | |||
| accessdate = 2006-03-17}}</ref> CryoCare ceased operations in 1999 when they were unable to renew their service contract with BioPreservation. CryoCare’s two patients stored at CryoSpan were transferred to ]. Several ] patients stored at CryoSpan were transferred to ]. | |||
] has written, "Cryonics might be a suitable subject for scientific research, but marketing an unproven method to the public is quackery".<ref name=butler>{{cite book |author=Butler K |title=A Consumer's Guide to "Alternative" Medicine |publisher=Prometheus Books |year=1992 |page=173}}</ref><ref name=q>{{cite web |website=The Skeptics Dictionary: A Collection of Strange Beliefs, Amusing Deceptions, and Dangerous Delusions |last=Carroll |first=Robert Todd|date =5 December 2013|title=Cryonics |authorlink=Robert Todd Carroll|quote=A business based on little more than hope for developments that can be imagined by science is quackery. There is little reason to believe that the promises of cryonics will ever be fulfilled |url=https://www.skepdic.com/cryonics.html}}</ref> | |||
There have been numerous, often transient, for-profit companies involved in cryonics. For-profit companies were often paired or affiliated with non-profit groups they served. Some of these companies, with non-profits they served in parentheses, were Cryonic Interment, Inc. (CSC), Cryo-Span Corporation (CSNY), Cryo-Care Equipment Corporation (CSC and CSNY), Manrise Corporation (]), CryoVita, Inc. (]), BioTransport, Inc. (]), Trans Time, Inc.<ref>{{cite web | |||
| url = http://www.transtime.com/ | |||
| title = Trans Time, Inc. | |||
| accessdate = 2006-03-17}}</ref> (BACS), Soma, Inc. (IABS), CryoSpan, Inc. (CryoCare and ]), BioPreservation, Inc. (CryoCare and ]), Kryos, Inc. (]), Suspended Animation, Inc.<ref>{{cite web | |||
| url = http://www.suspendedinc.com/ | |||
| title = Suspended Animation, Inc. | |||
| accessdate = 2006-03-17}}</ref> (], ], and ]). Only Trans Time and Suspended Animation still exist. Apparently none of the companies were ever profitable. The cryonics field seems to have largely consolidated around three non-profit groups, ], ] (CI), and the ] (ACS) all deriving significant income from bequests and donations. | |||
According to cryonicist Aschwin de Wolf and others, cryonics can often produce intense hostility from spouses who are not cryonicists. James Hughes, the executive director of the pro-life-extension ], has not personally signed up for cryonics, calling it a worthy experiment but saying, "I value my relationship with my wife."<ref name="nytimes do us part" /> | |||
As research in the 1990s revealed in greater detail the damaging effects of freezing, there was a trend to use higher concentrations of glycerol ] to prevent freezing injury. In 2001 Alcor began using ] (a technology borrowed from mainstream organ preservation research) in an attempt to completely prevent ice formation during cold preservation. Because ] technology could then only be applied to the head, heads and bodies were sometimes separated to optimize preservation of the brain, causing much public confusion. | |||
] Dayong Gao has said, "People can always have hope that things will change in the future, but there is no scientific foundation supporting cryonics at this time."<ref name="bbc frozen">{{cite news|title=Frozen body: Can we return from the dead?|url=http://www.bbc.co.uk/science/0/23695785|access-date=21 February 2016|publisher=BBC News|date=15 August 2013|archive-date=12 March 2016|archive-url=https://web.archive.org/web/20160312083619/http://www.bbc.co.uk/science/0/23695785|url-status=live}}</ref> While it is universally agreed that ] is uninterrupted when brain activity temporarily ceases during incidents of accidental drowning (where people have been restored to normal functioning after being completely submerged in cold water for up to 66 minutes), one argument against cryonics is that a centuries-long absence from life might interrupt personal identity, such that the revived person would "not be themself".<ref name="moen" /> | |||
In 2005 Alcor began applying ] (or attempted vitrification<ref>{{cite web | |||
| url = http://www.alcor.org/Library/html/newtechnology.html | |||
| title = New Cryopreservation Technology | |||
| publisher = Alcor Life Extension Foundation | |||
| accessdate = 2006-03-17}}</ref>) treatment to the whole body simultaneously without removal of the head. In the same year, the Cryonics Institute began using a new procedure in which the head was vitrified while still attached to the body, which was frozen without any ].<ref>{{cite web | |||
| author=] | |||
| title=The Cryonics Institute's 69th Patient | |||
| url=http://www.cryonics.org/reports/CI69.html | |||
| accessdate=2006-06-07}}</ref> | |||
A year later the Cryonics Institute began perfusing the body with ].<ref>{{cite web | |||
| author=] | |||
| title=The Cryonics Institute's 74th Patient | |||
| url=http://www.cryonics.org/reports/CI74.html | |||
| accessdate=2006-06-07}}</ref> | |||
] bioethicist David Shaw raises the argument that there would be no point in being revived in the far future if one's friends and families are dead, leaving them all alone, but he notes that family and friends can also be frozen, that there is "nothing to prevent the thawed-out freezee from making new friends", and that a lonely existence may be preferable to none at all.<ref name="shaw cryoethics" /> | |||
When the baseball star ] was ] by ] in 2002 a family dispute arose as to whether Ted had really wanted to be ]. Following a July, 2003 ] article claiming that Alcor had mishandled Ted Williams,<ref>{{cite journal | title=What happened to Ted?|journal= ] | year=2003| url = http://sportsillustrated.cnn.com/baseball/news/2003/08/12/williams_si/index.html | |||
}}</ref><ref>{{cite journal | title=Ted's tragedy unfolds | journal= ] | year=2003| url = http://sportsillustrated.cnn.com/inside_game/tom_verducci/news/2003/08/12/insider/index.html | |||
}}</ref><ref>{{cite journal | title=Renewed Ted Williams Controversy: An Interim Response | journal=] News Bulletin Number |issue=15 | year=2003| url = http://www.alcor.org/printable.cgi?fname=Library%2Fhtml%2Falcornews015.html | |||
}}</ref> Alcor had to fight for its existence in the ] legislature.<ref>{{cite web | |||
| url = http://www.alcor.org/printable.cgi?fname=Library%2Fhtml%2Flegislation.html | |||
| title = Chronology of Attempted 2004 Cryonics Legislation in Arizona | |||
| publisher = ] | |||
| year = 2004}}</ref> At minimum, Alcor could have been denied use of the ], which could have impaired its ability to gain rapid access to cryonics patients. Despite not being responsible for Ted Williams, the media blitz resulted in the ] (CI) being placed under a "Cease and Desist" order by the State of ] for six months. Finally the Michigan government decided to regulate CI as a ]. | |||
==In fiction== | |||
] currently maintains about 75 cryonics patients in ]. The ] also maintains about 75 human patients (along with about 40 pets) at its ], ] facility. There are support groups in ], ], ], and ]. There is also a small cryonics facility in ] storing two neuropatients called ], and plans for a facility in ]. | |||
{{main|Suspended animation in fiction}} | |||
] is a popular subject in science fiction and fantasy settings. It is often the means by which a character is transported into the future. The characters ] in '']'' and ] in '']'' exemplify this trope. | |||
A survey in Germany found that about half of the respondents were familiar with cryonics, and about half of those familiar with it had learned of it from films or television.<ref name="pmid24499638">{{cite journal |vauthors=Kaiser S, Gross D, Lohmeier J, Rosentreter M, Raschke J |title=Attitudes and acceptance toward the technology of cryonics in Germany |journal=International Journal of Technology Assessment in Health Care |volume=5 |issue=1 |pages=1–7 |year=2014 |pmid=24499638 |s2cid=41185307 |doi=10.1017/S0266462313000718}}</ref> | |||
==Culture== | |||
===Cryonics in mass culture=== | |||
Procedures similar to cryonics have been featured in innumerable ] stories to aid space travel, or as means to transport a character from the past into the future. In addition to accomplishing whatever the character's primary task is in the future, he or she must cope with the strangeness of a new world, which may contain only traces of their previous surroundings. This prospect of alienation is often cited as a major reason for the unpopularity of cryonics. | |||
==In popular culture== | |||
Relatively few stories have been published concerning the primary objective and definition of cryonics, which is medical time travel. Novels with this theme include the national best-seller '']'' by ], '']'' by ], '']'' by ], ''Chiller'' by Sterling Blake (aka ]), ''Ralph’s Journey'' by David Pizer, ''Formerly Brandewyne'' by Jude Liebermann, and ''I Was a Teenage Popsicle'' by Bev Katz Rosenbaum. A fictional book about cryonics specifically for children is ''21st Century Kids'' by ]<ref>{{cite web | title = 21st Century Kids | publisher = 21CenturyKids | date = 2007 | url = http://www.21stcenturykidsbook.com/ | accessdate 2007-03-08 }}</ref> <ref>{{cite book | authorlink = ] | title = 21st Century Kids | publisher = ] | date = March 15, 2007 | isbn = 1886057001}}</ref>. | |||
The town of ], hosts an annual ] festival to commemorate a substandard attempt at ].<ref>{{cite web |last=McPheeters |first=Sam |title=Home Cryonics in the Smirk Age |work=The Corpse |publisher=ViceLand.com |date=May 2010 |url=http://www.viceland.com/int/v17n5/htdocs/the-corpse-428.php |access-date=2020-01-11 |url-status=dead |archive-url=https://web.archive.org/web/20110717195908/http://www.viceland.com/int/v17n5/htdocs/the-corpse-428.php |archive-date=2011-07-17}}</ref> | |||
== Notable people == | |||
A 1931 short story by ] called '']'' has been credited with giving ] the seed of the idea of cryonics when he was a teenager. | |||
{{see also|List of people who arranged for cryonics}} | |||
Corpses subjected to the cryonics process include those of baseball players ] and his son ] (in 2002 and 2004, respectively),<ref>{{cite web|url=https://www.espn.com/mlb/news/story?id=1753358|title=Leukemia claims son of Hall of Famer |work=ESPN.com |date=2004-03-07|access-date=2016-02-18|archive-date=2016-01-05|archive-url=https://web.archive.org/web/20160105223704/http://sports.espn.go.com/mlb/news/story?id=1753358|url-status=live}}</ref> engineer and doctor ] (in 2014),<ref>{{cite web|url=https://www.latimes.com/local/obituaries/la-me-stephen-coles-20141205-story.html|title=L. Stephen Coles dies at 73; studied extreme aging in humans|author=Steve Chawkins |date=4 December 2014|work=Los Angeles Times|access-date=17 April 2020|archive-date=27 December 2017|archive-url=https://web.archive.org/web/20171227213836/http://www.latimes.com/local/obituaries/la-me-stephen-coles-20141205-story.html|url-status=live}}</ref> economist and entrepreneur ], and software engineer ] (in 2014).<ref>{{cite magazine|url=https://www.wired.com/2014/08/hal-finney/|title=Bitcoin's Earliest Adopter Is Cryonically Freezing His Body to See the Future |url-access=limited |first1=Andy |last1=Greenberg |magazine=WIRED|date=2014-08-29|access-date=2017-03-06|archive-date=2018-08-03|archive-url=https://web.archive.org/web/20180803052532/https://www.wired.com/2014/08/hal-finney/|url-status=live}}</ref> | |||
People known to have arranged for cryonics upon death include ] founders ]<ref name=Thiel2014>{{cite book|last1=Thiel|first1=Peter|title=]: Notes on Startups, or How to Build the Future|date=September 16, 2014|publisher=Crown Business|isbn=978-0-8041-3929-8|page=1 (chapter 14)}}</ref> and ],<ref name=Brown2014>{{cite news|last=Brown|first=Mick|title=Peter Thiel: the billionaire tech entrepreneur on a mission to cheat death|url=https://www.telegraph.co.uk/technology/11098971/Peter-Thiel-the-billionaire-tech-entrepreneur-on-a-mission-to-cheat-death.html|access-date=16 October 2014|work=The Telegraph|date=19 September 2014|archive-date=18 October 2014|archive-url=https://web.archive.org/web/20141018164619/http://www.telegraph.co.uk/technology/11098971/Peter-Thiel-the-billionaire-tech-entrepreneur-on-a-mission-to-cheat-death.html|url-status=live}}</ref> Oxford ]s ] and ], and transhumanist philosopher ].<ref>{{cite web |last=Pearce |first=David |title=Quora Answers 2015 – 2022 by David Pearce|url=https://www.hedweb.com/quora/2015.html#cryonics|archive-url=https://web.archive.org/web/20220116063509/https://www.hedweb.com/quora/2015.html|archive-date=January 16, 2022|website=The Hedonistic Imperative}}</ref> ] once arranged for cryonics but, according to '']'', changed his mind.<ref>{{cite web|title=Was Larry King Cryogenically Frozen After his Death?|publisher=]|url=https://www.insideedition.com/was-larry-king-cryogenically-frozen-after-his-death-64558|date=2021-01-27|access-date=2021-01-30}}</ref><ref>{{cite news |newspaper=New York Times |title=Larry King Is Preparing for the Final Cancellation |url=https://www.nytimes.com/2015/08/30/magazine/larry-king-is-preparing-for-the-final-cancellation.html |vauthors=Leibovich M |date=26 August 2015 |access-date=14 February 2020 |archive-date=6 December 2019 |archive-url=https://web.archive.org/web/20191206164249/https://www.nytimes.com/2015/08/30/magazine/larry-king-is-preparing-for-the-final-cancellation.html |url-status=live}}</ref> | |||
An unusual fictional application of cryonics is rescue after freezing in space. ]'s '']'' reveals that ], murdered by ] in '']'' was cryopreserved by his exposure to space, and found and revived a thousand years later. The short story "Wait It Out" by ] depicts a sort of emergency self-cryopreservation by a man marooned on Pluto. | |||
Sex offender and financier ] wanted to have his head and ] frozen after death.<ref name=jenyt>{{cite news |newspaper=The New York Times |title=Jeffrey Epstein Hoped to Seed Human Race With His DNA |url=https://www.nytimes.com/2019/07/31/business/jeffrey-epstein-eugenics.html |vauthors=Stewart JB, Goldstein M, Silver-Greenberg J |date=31 July 2019 |access-date=3 November 2019 |archive-date=31 July 2019 |archive-url=https://web.archive.org/web/20190731235929/https://www.nytimes.com/2019/07/31/business/jeffrey-epstein-eugenics.html |url-status=live}}</ref><ref name=jenw>{{cite news |newspaper=Newsweek |title=Jeffrey Epstein Wanted to Freeze His Head and Penis After Dying: Report |url=https://www.newsweek.com/jeffrey-epstein-freeze-head-penis-cryonics-1452065 |author=Croucher S |date=1 August 2019 |access-date=3 November 2019 |archive-date=31 October 2019 |archive-url=https://web.archive.org/web/20191031204954/https://www.newsweek.com/jeffrey-epstein-freeze-head-penis-cryonics-1452065 |url-status=live}}</ref> | |||
Movies featuring cryonics for medical purposes include the ] comedy, '']'', and the films '']'' and '']'' (remade as '']''). One of the most famous movies regarding a cryonics-like process was 1992's '']'', starring Mel Gibson. Although not about cryonics per se, the ] film '']'' has been hailed by cryonics advocates as expressing the values motivating cryonics better than any other film.<ref>{{cite book | |||
| url = http://www.alcor.org/cryonics/cryonics8508.txt | |||
| title = Cryonics | |||
| publisher = Alcor Life Extension Foundation | |||
| year = 1985 | |||
| edition = Volume 6 Issue 61 | |||
| accessdate = 2006-03-17}}</ref> | |||
The corpses of some are mistakenly believed to have undergone cryonics. The ] that ]'s remains were cryopreserved is false; it was cremated and interred at ].<ref>{{cite news |last=Mikkelson |first=David |title=FACT CHECK: Was Walt Disney Frozen? |url=https://www.snopes.com/fact-check/suspended-animation/ |website=] |date=19 October 1995 |access-date=21 January 2019 |archive-date=23 January 2021 |archive-url=https://web.archive.org/web/20210123132948/https://www.snopes.com/fact-check/suspended-animation/ |url-status=live}}</ref>{{efn|Robert Nelson told the '']'' that he thought Walt Disney wanted to be cryopreserved, for ] had called him to ask detailed questions about his organisation, the Cryonics Society of California. However, Nelson clarified that "They had him cremated. I personally have seen his ashes."<ref>{{cite web|url=http://mentalfloss.com/article/54196/disney-ice-truth-about-walt-disney-and-cryogenics|title=Disney on Ice: The Truth About Walt Disney and Cryogenics|last=Conradt|first=Stacy|date=15 December 2013|website=]|access-date=21 January 2019|archive-date=10 January 2019|archive-url=https://web.archive.org/web/20190110183415/http://mentalfloss.com/article/54196/disney-ice-truth-about-walt-disney-and-cryogenics|url-status=live}}</ref>}} ] was a long-time cryonics advocate and signed up with a major cryonics provider, but changed his mind shortly before his death and was not cryopreserved.<ref> ''The New York Times'', "A Final Turn-On Lifts Timothy Leary Off" by Marlise Simons, 22 April 1997</ref> | |||
On television, producer ] wrote portrayals of cryonics for the TV shows '']'' (1990 episode<ref>{{cite web | |||
| url = http://www.imdb.com/title/tt0624130/ | |||
| title = "L.A. Law" The Good Human Bar (1990) | |||
| publisher = IMDb | |||
| accessdate = 2006-03-17}}</ref>), '']'' (1994 episode<ref>{{cite web | |||
| url = http://www.imdb.com/title/tt0674696/ | |||
| publisher = IMDb | |||
| title = "Picket Fences" Frosted Flakes (1994) | |||
| accessdate = 2006-03-17}}</ref>), and '']'' | |||
(2005 episode<ref>{{cite web | |||
| url = http://www.imdb.com/title/tt0530525/ | |||
| title = "Boston Legal" Let Sales Ring (2005) | |||
| publisher = IMDb | |||
| accessdate = 2006-03-17}}</ref>). In each case, there was a dying plaintiff petitioning a court for the right to elective ]. The ] episode of ] "The Big Thaw" featured a cryopreserved ] singer whose wife wants his revival stopped so she can inherit his estate. The episode "When We Dead Awaken" of '']'' features Lieutenant James Brody's mother having been placed in cryonic stasis following a terminal infection. The last two television works of ] use Cryonics. In ] the terminally ill central character Daniel Feeld (]) arranges to have his head preserved by Cryonics while in ] Feelds head is revived by future scientists and his memories replayed. Cryonics was also satirized by the comedy cartoon series '']'', in which the character, ], is accidentally ] at the turn of the millennium on ] ], and revived on ] ], a thousand years later. | |||
Comic books also feature characters that have been affected by cryonics. The future society depicted in ]'s series ] includes 'revivals,' that is, individuals who had been cryonically preserved in centuries past and then revived. In ], ] was placed into cryonic suspension following his apparent death due to heart failure. | |||
Songs about cryonics include "Crionics" by ] (from the album ]) and "Gelid Remains" by Demolition Hammer (from the album "Tortured Existence"). | |||
In ], epsidode #26 ] depicts three 20th century cryonically frozen humans in space, who are subsequently revived. | |||
In the videogame ], the first level starts with Master Chief being revived from a cryotube | |||
===The subculture of cryonicists=== | |||
Cryonicists have been able to form cryonics societies in highly populated areas (see ]), have regular meetings, publish magazines and hold conferences. ] and Evan Cooper as well as ] were active in organizing cryonics conferences in the early years of cryonics. The magazines of the cryonics organizations have also helped keep members of the cryonics community informed about events and common problems. On July 24, 1988 a ] in ] named Kevin Brown started an ] called ''CryoNet''<ref>{{cite web | |||
| url = http://www.cryonet.org/ | |||
| title = CryoNet | |||
| accessdate = 2006-03-17}}</ref> that became a powerful tool of communication for the cryonics community. Numerous other mailing lists and web forums for discussing cryonics and the affairs of particular organizations have since appeared, but CryoNet remains a central point of contact for cryonicists. | |||
Cryonicists have also had a common jargon, including their use of the words ''patient'', ''death'', ''deanimation'' and ''suspension''. The phrase ''cryonic suspension'' to describe ] is falling into disfavor, partly because cryopreservation is not really ] and human bodies or heads are not buoyant enough in ] to be suspended. As in other subcultures, some members of the community can have strong feelings about the use of "]" cryonics language. | |||
==See also== | ==See also== | ||
<!-- PLEASE RESPECT ALPHABETICAL ORDER --> | |||
* ] | |||
* ] | |||
* ] | |||
* ] | * ] | ||
* ] | * ] | ||
* ] | |||
* ] | |||
* ] | |||
* ] | |||
* ] | |||
* ] | |||
* ] | |||
* ] | * ] | ||
* ] | * ] | ||
* ] | |||
* ] | |||
* ] | * ] | ||
* ] | |||
* ] | |||
==References== | ==References== | ||
=== Footnotes === | |||
<div class="references-small"><references/></div> | |||
{{notelist}} | |||
=== Citations === | |||
{{reflist}} | |||
== Further reading == | |||
* {{cite episode |title=Mistakes Were Made |url=https://www.thisamericanlife.org/354/mistakes-were-made |series=This American Life |series-link=This American Life |network=] |station=] |date=18 April 2008 |number=354 |transcript=Transcript |transcript-url=https://www.thisamericanlife.org/354/transcript}} | |||
==External links== | ==External links== | ||
{{Wikiquote}} | |||
* | |||
{{Commons category}} | |||
* | |||
* | |||
* | |||
* | |||
* | |||
* | |||
* | |||
* | |||
* | |||
* | |||
* | |||
* | |||
{{Cryonics|state=expanded}} | |||
] | |||
{{Death}} | |||
{{Pseudoscience}} | |||
] | |||
] | ] | ||
] | |||
] | ] | ||
] | ] | ||
] | ] | ||
] | |||
] | |||
] | |||
] | |||
] | |||
] | |||
] | |||
] | |||
] | |||
] |
Latest revision as of 05:09, 23 December 2024
Freezing of a corpse with the intent of future revivalFor the study of the production of very low temperatures, see Cryogenics. For the low-temperature preservation of living tissue and organisms in general, see Cryopreservation. For the Hot Cross album, see Cryonics (album).
Cryonics (from Greek: κρύος kryos, meaning "cold") is the low-temperature freezing (usually at −196 °C or −320.8 °F or 77.1 K) and storage of human remains in the hope that resurrection may be possible in the future. Cryonics is regarded with skepticism by the mainstream scientific community. It is generally viewed as a pseudoscience, and its practice has been characterized as quackery.
Cryonics procedures can begin only after the "patients" are clinically and legally dead. Procedures may begin within minutes of death, and use cryoprotectants to try to prevent ice formation during cryopreservation. It is not possible to reanimate a corpse that has undergone vitrification, as that damages the brain, including its neural circuits. The first corpse to be frozen was that of James Bedford, in 1967. As of 2014, about 250 bodies had been cryopreserved in the United States, and 1,500 people had made arrangements for cryopreservation of their remains.
Economic considerations make it difficult for cryonics corporations to remain in business long enough to take advantage of any long-term benefits. The "patients", being dead, cannot continue to pay for their own preservation. Early attempts at cryonic preservation were made in the 1960s and early 1970s; most relied on family members to pay for the preservation and ended in failure, with all but one of the corpses cryopreserved before 1973 thawed and disposed of.
Conceptual basis
Cryonicists argue that as long as brain structure remains intact, there is no fundamental barrier, given our current understanding of physics, to recovering its information content. Cryonics proponents go further than the mainstream consensus in saying that the brain does not have to be continuously active to survive or retain memory. Cryonicists controversially say that a human can survive even within an inactive, badly damaged brain, as long as the original encoding of memory and personality can be adequately inferred and reconstituted from what remains.
Cryonics uses temperatures below −130 °C, called cryopreservation, in an attempt to preserve enough brain information to permit the revival of the cryopreserved person. Cryopreservation is accomplished by freezing with or without cryoprotectant to reduce ice damage, or by vitrification to avoid ice damage. Even using the best methods, cryopreservation of whole bodies or brains is very damaging and irreversible with current technology.
Cryonicists call the human remains packed into low-temperature vats "patients". They hope that some kind of presently nonexistent nanotechnology will be able to bring the dead back to life and treat the diseases that killed them. Mind uploading has also been proposed.
Cryonics in practice
Cryonics can be expensive. As of 2018, the cost of preparing and storing corpses using cryonics ranged from US$28,000 to $200,000.
At high concentrations, cryoprotectants can stop ice formation completely. Cooling and solidification without crystal formation is called vitrification. In the late 1990s, cryobiologists Gregory Fahy and Brian Wowk developed the first cryoprotectant solutions that could vitrify at very slow cooling rates while still allowing whole organ survival, for the purpose of banking transplantable organs. This has allowed animal brains to be vitrified, thawed, and examined for ice damage using light and electron microscopy. No ice crystal damage was found; cellular damage was due to dehydration and toxicity of the cryoprotectant solutions.
Costs can include payment for medical personnel to be on call for death, vitrification, transportation in dry ice to a preservation facility, and payment into a trust fund intended to cover indefinite storage in liquid nitrogen and future revival costs. As of 2011, U.S. cryopreservation costs can range from $28,000 to $200,000, and are often financed via life insurance. KrioRus, which stores bodies communally in large dewars, charges $12,000 to $36,000 for the procedure. Some customers opt to have only their brain cryopreserved ("neuropreservation"), rather than their whole body.
As of 2014, about 250 corpses have been cryogenically preserved in the U.S., and around 1,500 people have signed up to have their remains preserved. As of 2016, there are four facilities that retain cryopreserved bodies, three in the U.S. and one in Russia.
A more recent development is Tomorrow Biostasis GmbH, a Berlin-based firm offering cryonics and standby and transportation services in Europe. Founded in 2019 by Emil Kendziorra and Fernando Azevedo Pinheiro, it partners with the European Biostasis Foundation in Switzerland for long-term corpse storage. The facility was completed in 2022.
It seems extremely unlikely that any cryonics company could exist long enough to take advantage of the supposed benefits offered; historically, even the most robust corporations have only a one-in-a-thousand chance of lasting 100 years. Many cryonics companies have failed; as of 2018, all but one of the pre-1973 batch had gone out of business, and their stored corpses have been defrosted and disposed of.
Obstacles to success
Preservation damage
Medical laboratories have long used cryopreservation to maintain animal cells, human embryos, and even some organized tissues, for periods as long as three decades. But recovering large animals and organs from a frozen state is not considered possible now. Large vitrified organs tend to develop fractures during cooling, a problem worsened by the large tissue masses and very low temperatures of cryonics. Without cryoprotectants, cell shrinkage and high salt concentrations during freezing usually prevent frozen cells from functioning again after thawing. Ice crystals can also disrupt connections between cells that are necessary for organs to function.
Some cryonics organizations use vitrification without a chemical fixation step, sacrificing some structural preservation quality for less damage at the molecular level. Some scientists, like João Pedro Magalhães, have questioned whether using a deadly chemical for fixation eliminates the possibility of biological revival, making chemical fixation unsuitable for cryonics.
Outside of cryonics firms and cryonics-linked interest groups, many scientists are very skeptical about cryonics methods. Cryobiologist Dayong Gao has said, "we simply don't know if been damaged to the point where they've 'died' during vitrification because the subjects are now inside liquid nitrogen canisters." Based on experience with organ transplants, biochemist Ken Storey argues that "even if you only wanted to preserve the brain, it has dozens of different areas which would need to be cryopreserved using different protocols".
Revival
Revival would require repairing damage from lack of oxygen, cryoprotectant toxicity, thermal stress (fracturing), and freezing in tissues that do not successfully vitrify, followed by reversing the cause of death. In many cases, extensive tissue regeneration would be necessary. This revival technology remains speculative.
Legal issues
Historically, people had little control over how their bodies were treated after death, as religion held jurisdiction over the matter. But secular courts began to exercise jurisdiction over corpses and use discretion in carrying out deceased people's wishes. Most countries legally treat preserved bodies as deceased persons because of laws that forbid vitrifying someone who is medically alive. In France, cryonics is not considered a legal mode of body disposal; only burial, cremation, and formal body donation to science are allowed, though bodies may legally be shipped to other countries for cryonic freezing. As of 2015, British Columbia prohibits the sale of arrangements for cryonic body preservation. In Russia, cryonics falls outside both the medical industry and the funeral services industry, making it easier than in the U.S. to get hospitals and morgues to release cryonics candidates.
In 2016, the English High Court ruled in favor of a mother's right to seek cryopreservation of her terminally ill 14-year-old daughter, as the girl wanted, contrary to the father's wishes. The decision was made on the basis that the case represented a conventional dispute over the disposal of the girl's body, although the judge urged ministers to seek "proper regulation" for the future of cryonic preservation after the hospital raised concerns about the competence and professionalism of the team that conducted the preservation procedures. In Alcor Life Extension Foundation v. Richardson, the Iowa Court of Appeals ordered the disinterment of Richardson, who was buried against his wishes, for cryopreservation.
A detailed legal examination by Jochen Taupitz concludes that cryonic storage is legal in Germany for an indefinite period.
Ethics
Writing in Bioethics in 2009, David Shaw examined cryonics. The arguments he cited against it included changing the concept of death, the expense of preservation and revival, lack of scientific advancement to permit revival, temptation to use premature euthanasia, and failure due to catastrophe. Arguments in favor of cryonics include the potential benefit to society, the prospect of immortality, and the benefits associated with avoiding death. Shaw explores the expense and the potential payoff, and applies an adapted version of Pascal's Wager to the question.
In 2016, Charles Tandy wrote in support of cryonics, arguing that honoring someone's last wishes is seen as a benevolent duty in American and many other cultures.
History
See also: Cryopreservation § History, and Embryo cryopreservationCryopreservation was applied to human cells beginning in 1954 with frozen sperm, which was thawed and used to inseminate three women. The freezing of humans was first scientifically proposed by Michigan professor Robert Ettinger in The Prospect of Immortality (1962). In 1966, the first human body was frozen—though it had been embalmed for two months—by being placed in liquid nitrogen and stored at just above freezing. The middle-aged woman from Los Angeles, whose name is unknown, was soon thawed and buried by relatives.
The first body to be cryopreserved and then frozen in hope of future revival was that of James Bedford. Alcor's Mike Darwin says Bedford's body was cryopreserved around two hours after his death by cardiorespiratory arrest (secondary to metastasized kidney cancer) on January 12, 1967. Bedford's corpse is the only one frozen before 1974 still preserved today. In 1976, Ettinger founded the Cryonics Institute; his corpse was cryopreserved in 2011. In 1981, Robert Nelson, "a former TV repairman with no scientific background" who led the Cryonics Society of California, was sued for allowing nine bodies to thaw and decompose in the 1970s; in his defense, he claimed that the Cryonics Society had run out of money. This lowered the reputation of cryonics in the U.S.
In 2018, a Y-Combinator startup called Nectome was recognized for developing a method of preserving brains with chemicals rather than by freezing. The method is fatal, performed as euthanasia under general anesthesia, but the hope is that future technology will allow the brain to be physically scanned into a computer simulation, neuron by neuron.
Demographics
According to The New York Times, cryonicists are predominantly non-religious white men, outnumbering women by about three to one. According to The Guardian, as of 2008, while most cryonicists used to be young, male, and "geeky", recent demographics have shifted slightly toward whole families.
In 2015, Du Hong, a 61-year-old female writer of children's literature, became the first known Chinese national to have her head cryopreserved.
Reception
Cryonics is generally regarded as a fringe pseudoscience. Between 1982 and November 2018, the Society for Cryobiology rejected members who practiced cryonics, and issued a public statement saying that cryonics "is an act of speculation or hope, not science", and as such outside the scope of the Society.
Russian company KrioRus is the first non-U.S. vendor of cryonics services. Yevgeny Alexandrov, chair of the Russian Academy of Sciences commission against pseudoscience, said there was "no scientific basis" for cryonics, and that the company was based on "unfounded speculation".
Scientists have expressed skepticism about cryonics in media sources, and the Norwegian philosopher Ole Martin Moen has written that the topic receives a "minuscule" amount of attention in academia.
While some neuroscientists contend that all the subtleties of a human mind are contained in its anatomical structure, few will comment directly on cryonics due to its speculative nature. People who intend to be frozen are often "looked at as a bunch of kooks". Cryobiologist Kenneth B. Storey said in 2004 that cryonics is impossible and will never be possible, as cryonics proponents are proposing to "overturn the laws of physics, chemistry, and molecular science". Neurobiologist Michael Hendricks has said, "Reanimation or simulation is an abjectly false hope that is beyond the promise of technology and is certainly impossible with the frozen, dead tissue offered by the 'cryonics' industry".
Anthropologist Simon Dein writes that cryonics is a typical pseudoscience because of its lack of falsifiability and testability. In his view, cryonics is not science, but religion: it places faith in nonexistent technology and promises to overcome death.
William T. Jarvis has written, "Cryonics might be a suitable subject for scientific research, but marketing an unproven method to the public is quackery".
According to cryonicist Aschwin de Wolf and others, cryonics can often produce intense hostility from spouses who are not cryonicists. James Hughes, the executive director of the pro-life-extension Institute for Ethics and Emerging Technologies, has not personally signed up for cryonics, calling it a worthy experiment but saying, "I value my relationship with my wife."
Cryobiologist Dayong Gao has said, "People can always have hope that things will change in the future, but there is no scientific foundation supporting cryonics at this time." While it is universally agreed that personal identity is uninterrupted when brain activity temporarily ceases during incidents of accidental drowning (where people have been restored to normal functioning after being completely submerged in cold water for up to 66 minutes), one argument against cryonics is that a centuries-long absence from life might interrupt personal identity, such that the revived person would "not be themself".
Maastricht University bioethicist David Shaw raises the argument that there would be no point in being revived in the far future if one's friends and families are dead, leaving them all alone, but he notes that family and friends can also be frozen, that there is "nothing to prevent the thawed-out freezee from making new friends", and that a lonely existence may be preferable to none at all.
In fiction
Main article: Suspended animation in fictionSuspended animation is a popular subject in science fiction and fantasy settings. It is often the means by which a character is transported into the future. The characters Philip J. Fry in Futurama and Khan Noonien Singh in Star Trek exemplify this trope.
A survey in Germany found that about half of the respondents were familiar with cryonics, and about half of those familiar with it had learned of it from films or television.
In popular culture
The town of Nederland, Colorado, hosts an annual Frozen Dead Guy Days festival to commemorate a substandard attempt at cryopreservation.
Notable people
See also: List of people who arranged for cryonicsCorpses subjected to the cryonics process include those of baseball players Ted Williams and his son John Henry Williams (in 2002 and 2004, respectively), engineer and doctor L. Stephen Coles (in 2014), economist and entrepreneur Phil Salin, and software engineer Hal Finney (in 2014).
People known to have arranged for cryonics upon death include PayPal founders Luke Nosek and Peter Thiel, Oxford transhumanists Nick Bostrom and Anders Sandberg, and transhumanist philosopher David Pearce. Larry King once arranged for cryonics but, according to Inside Edition, changed his mind.
Sex offender and financier Jeffrey Epstein wanted to have his head and penis frozen after death.
The corpses of some are mistakenly believed to have undergone cryonics. The urban legend that Walt Disney's remains were cryopreserved is false; it was cremated and interred at Forest Lawn Memorial Park Cemetery. Timothy Leary was a long-time cryonics advocate and signed up with a major cryonics provider, but changed his mind shortly before his death and was not cryopreserved.
See also
- Aldehyde-stabilized cryopreservation
- Brain in a vat
- Cryptobiosis
- Deep hypothermic circulatory arrest
- Emergency Preservation and Resuscitation
- Extropianism
- Hibernation
- Life extension
- Supercooling
- Targeted temperature management
- Technological utopianism
References
Footnotes
- Robert Nelson told the Los Angeles Times that he thought Walt Disney wanted to be cryopreserved, for Walt Disney Studios had called him to ask detailed questions about his organisation, the Cryonics Society of California. However, Nelson clarified that "They had him cremated. I personally have seen his ashes."
Citations
- ^ McKie, Robin (13 July 2002). "Cold facts about cryonics". The Observer. Archived from the original on 8 July 2017. Retrieved 1 December 2013.
Cryonics, which began in the Sixties, is the freezing – usually in liquid nitrogen – of human beings who have been legally declared dead. The aim of this process is to keep such individuals in a state of refrigerated limbo so that it may become possible in the future to resuscitate them, cure them of the condition that killed them, and then restore them to functioning life in an era when medical science has triumphed over the activities of the Grim Reaper.
- ^ "Dying is the last thing anyone wants to do – so keep cool and carry on". The Guardian. 10 October 2015. Archived from the original on 3 July 2017. Retrieved 21 February 2016.
- ^ Steinbeck RL (29 September 2002). "Mainstream science is frosty over keeping the dead on ice". Chicago Tribune. Archived from the original on 17 July 2019. Retrieved 17 July 2019.
- ^ Butler K (1992). A Consumer's Guide to "Alternative" Medicine. Prometheus Books. p. 173.
- ^ Carroll, Robert Todd (5 December 2013). "Cryonics". The Skeptics Dictionary: A Collection of Strange Beliefs, Amusing Deceptions, and Dangerous Delusions.
A business based on little more than hope for developments that can be imagined by science is quackery. There is little reason to believe that the promises of cryonics will ever be fulfilled
- Hendry, Robert; Crippen, David (2014). "Brain Failure and Brain Death". ACS Surgery: Principles and Practice critical care. Decker Intellectual Properties Inc. pp. 1–10. Archived from the original on 23 January 2021. Retrieved 3 March 2016.
A physician will pronounce a patient using the usual cardiorespiratory criteria, whereupon the patient is legally dead. Following this pronouncement, the rules pertaining to procedures that can be performed change radically because the individual is no longer a living patient but a corpse. In the initial cryopreservation protocol, the subject is intubated and mechanically ventilated, and a highly efficient mechanical cardiopulmonary resuscitation device reestablishes circulation.
- Best BP (April 2008). "Scientific justification of cryonics practice" (PDF). Rejuvenation Research. 11 (2): 493–503. doi:10.1089/rej.2008.0661. PMC 4733321. PMID 18321197. Archived from the original (PDF) on 21 July 2018. Retrieved 26 December 2013.
- ^ Miller K (2004). "Cryonics redux: is vitrification a viable alternative to immortality as a popsicle?". Skeptic. 11 (1): 24.
- Devlin, Hannah (18 November 2016). "The cryonics dilemma: will deep-frozen bodies be fit for new life?". The Guardian. Archived from the original on 24 January 2019. Retrieved 21 January 2019.
- "Death To Dust: What Happens To Dead Bodies? 2nd Edition, Chapter 7: Souls On Ice". Archived from the original on 27 March 2019. Retrieved 21 March 2016.
- ^ Moen, OM (August 2015). "The case for cryonics". Journal of Medical Ethics. 41 (18): 493–503. doi:10.1136/medethics-2015-102715. PMID 25717141. S2CID 31744039.
- ^ Stodolsky DS (2016). "The growth and decline of cryonics". Cogent Social Sciences. 2 (1): 1167576. doi:10.1080/23311886.2016.1167576.
- ^ "The law on cryonics". Human Tissue Authority. 26 September 2018. Archived from the original on 30 September 2019. Retrieved 3 October 2019.
- Doyle, DJ (2012). "Cryonic Life Extension: Scientific Possibility or Stupid Pipe Dream?". Ethics in Biology, Engineering and Medicine. 3 (1–3): 9–28. doi:10.1615/EthicsBiologyEngMed.2013006985.
- Germain J (21 October 2022). "200 Frozen Heads and Bodies Await Revival at This Arizona Cryonics Facility". Smithsonian Magazine.
- Crippen, DW; Whetstine, L (2007). "Ethics review: Dark angels – the problem of death in intensive care". Critical Care. 11 (1): 202. doi:10.1186/cc5138. PMC 2151911. PMID 17254317.
- "Frozen in time: Oregon firm preserves bodies, brains in hopes that science catches up". Portland Tribune. 18 February 2016. Archived from the original on 11 July 2017. Retrieved 21 February 2016.
- "Things to consider when making your decision on cryonics". Human Tissue Authority. 26 September 2018. Archived from the original on 30 September 2019. Retrieved 3 October 2019.
- Fahy GM, MacFarlane DR, Angell CA, Meryman HT (August 1984). "Vitrification as an approach to cryopreservation". Cryobiology. 21 (4): 407–26. doi:10.1016/0011-2240(84)90079-8. PMID 6467964.
- ^ Fahy GM, Wowk B, Pagotan R, et al. (July 2009). "Physical and biological aspects of renal vitrification". Organogenesis. 5 (3): 167–75. doi:10.4161/org.5.3.9974. PMC 2781097. PMID 20046680.
- Fahy GM, Wowk B, Wu J, et al. (April 2004). "Cryopreservation of organs by vitrification: perspectives and recent advances". Cryobiology. 48 (2): 157–78. doi:10.1016/j.cryobiol.2004.02.002. PMID 15094092.
- Fahy, G; Wowk, B; Wu, J; Phan, J; Rasch, C; Chang, A; Zendejas, E (2005). "Corrigendum to "Cryopreservation of organs by vitrification: perspectives and recent advances" ". Cryobiology. 50 (3): 344. doi:10.1016/j.cryobiol.2005.03.002.
- Lemler J, Harris SB, Platt C, Huffman TM (June 2004). "The arrest of biological time as a bridge to engineered negligible senescence". Annals of the New York Academy of Sciences. 1019 (1): 559–563. Bibcode:2004NYASA1019..559L. doi:10.1196/annals.1297.104. PMID 15247086. S2CID 27635898.
- ^ "Cryonics: the chilling facts". The Independent. 26 July 2011. Archived from the original on 14 June 2018. Retrieved 21 February 2016.
- "A Dying Young Woman's Hope in Cryonics and a Future". The New York Times. 12 September 2015. Archived from the original on 2 August 2018. Retrieved 21 February 2016.
- ^ "Inside the weird world of cryonics". Financial Times. 18 December 2015. Archived from the original on 8 September 2016. Retrieved 21 February 2016.
- "'The ultimate lottery ticket:' Inside one of four cryonics facilities in the world". KOIN (CBS Portland). 18 February 2016. Archived from the original on 4 July 2017. Retrieved 21 February 2016.
- "Tomorrow Biostasis". Archived from the original on 15 November 2023. Retrieved 26 December 2023.
- "'Want to live longer? This Berlin startup aims to bring you back from the dead". tech.eu. 26 January 2023. Archived from the original on 11 August 2023. Retrieved 26 December 2023.
- Crippen DW, Reis RJ, Risco R, Vita N (October 2015). "The Science Surrounding Cryonics". MIT Technology Review.
- Smith Audrey U (1957). "Problems in the Resuscitation of Mammals from Body Temperatures Below 0 °C". Proceedings of the Royal Society of London. Series B, Biological Sciences. 147 (929): 533–44. Bibcode:1957RSPSB.147..533S. doi:10.1098/rspb.1957.0077. JSTOR 83173. PMID 13494469. S2CID 40568140.
- Fahy GM, Wowk B, Wu J (2006). "Cryopreservation of complex systems: the missing link in the regenerative medicine supply chain" (PDF). Rejuvenation Research. 9 (2): 279–291. CiteSeerX 10.1.1.539.7419. doi:10.1089/rej.2006.9.279. PMID 16706656. Archived (PDF) from the original on 25 October 2017. Retrieved 24 October 2017.
- Fahy GM, Saur J, Williams RJ (October 1990). "Physical problems with the vitrification of large biological systems". Cryobiology. 27 (5): 492–510. doi:10.1016/0011-2240(90)90038-6. PMID 2249453.
- Wowk B (2011). "Systems for Intermediate Temperature Storage for Fracture Reduction and Avoidance". Cryonics. Vol. 2011, no. 3. Alcor Life Extension Foundation. pp. 7–13. ISSN 1054-4305.
- Fahy GM, Levy DI, Ali SE (June 1987). "Some Emerging Principles Underlying the Physical Properties, Biological Actions, and Utility of Vitrification Solutions". Cryobiology. 24 (3): 196–213. doi:10.1016/0011-2240(87)90023-X. PMID 3595164.
- "Alcor Position Statement on Brain Preservation Prize". Alcor Life Extension Foundation. 12 February 2016. Archived from the original on 15 February 2016. Retrieved 20 March 2016.
- "Mammal brain frozen and thawed out perfectly for first time". New Scientist. Archived from the original on 16 June 2016. Retrieved 6 June 2016.
- ^ "Frozen body: Can we return from the dead?". BBC News. 15 August 2013. Archived from the original on 12 March 2016. Retrieved 21 February 2016.
- Karow, Armand; Webb, Watts (1965). "Tissue Freezing: A theory for injury and survival". Cryobiology. 2 (3): 99–108. doi:10.1016/s0011-2240(65)80094-3. PMID 5860601.
- ^ Dukeminier, Jesse; Sitkoff, Robert (2013). Wills, Trusts, and Estates. Wolters Kluwer Law & Business in New York. p. 507. ISBN 978-1-4548-2457-2.
- ^ "Patients who are frozen in time". TheGuardian.com. 14 February 2008. Archived from the original on 12 May 2019. Retrieved 12 October 2020.
- "Conseil d'État du 06/01/2006, n° 260307: Cryogénisation – interdiction". Archived from the original on 7 January 2014. Retrieved 7 January 2014.
- Chrisafis, Angelique (16 March 2006). "Freezer failure ends couple's hopes of life after death". The Guardian. Archived from the original on 8 January 2014. Retrieved 8 January 2014.
- Proctor, Jason (16 July 2015). "Immortality sought through B.C. Supreme Court lawsuit". CBC News. Archived from the original on 21 February 2016. Retrieved 21 February 2016.
- "Terminally ill teen won historic ruling to preserve body". BBC News. 18 November 2016. Archived from the original on 18 November 2016. Retrieved 18 November 2016.
- "Alcor Life Extension Foundation v. Richardson". 785 N.W.2d 717. 2010. Archived from the original on 7 January 2017. Retrieved 7 January 2017.
- Taupitz, Jochen; Fuhr, Günther; Zwick, Anna; Salkic, Amina (2013). Unterbrochenes Leben?. St. Ingbert, Germany: Fraunhofer Verlag. ISBN 978-3-8396-0593-6. Archived from the original on 27 December 2018. Retrieved 26 December 2018.
- ^ Shaw, David. "Cryoethics: seeking life after death", Bioethics 23.9 (2009): 515–521. APA
- Tandy, Charles (8 February 2017). "An Open Letter to Physicians in Death-with-Dignity States (The Case of a Terminally Ill Cryonicist)". SSRN 2913107.
- "Fatherhood After Death Has Now Been Proved Possible". Cedar Rapids Gazette. 9 April 1954.
- ^ Devlin, Hannah (18 November 2016). "The cryonics dilemma: will deep-frozen bodies be fit for new life?". The Guardian. Archived from the original on 23 September 2018. Retrieved 22 September 2018.
- ^ Perry, R. Michael (October 2014). "Suspension Failures – Lessons from the Early Days". ALCOR: Life Extension Foundation. Archived from the original on 16 April 2020. Retrieved 29 August 2018.
- Darwin, Mike (July 1991). "Dear Dr. Bedford (and those who will care for you after I do)". Cryonics. Archived from the original on 16 March 2020. Retrieved 23 August 2009.
- Regalado, Antonio (13 March 2018). "A startup is pitching a mind-uploading service that is "100 percent fatal"". MIT Technology Review. Archived from the original on 23 January 2021. Retrieved 22 March 2018.
- ^ Howley, Kerry (7 July 2010). "Until Cryonics Do Us Part". The New York Times Magazine. Archived from the original on 16 May 2016. Retrieved 2 February 2016.
- Stephen Chen (18 September 2015). "Cheating death? Elderly writer is the first known Chinese to embrace cryogenics, her head now frozen by lab in Arizona". South China Morning Post. Archived from the original on 20 September 2015. Retrieved 24 September 2015.
- Jerry D. Leaf (November 1982). "Cryo-82, The Big Freeze" (PDF). Cryonics. Alcor Life Extension Foundation. pp. 5–11, 24. Retrieved 3 December 2024.
There are other members of the Society for Cryobiology that are involved in cryonics, but have been told they would be excluded from their chosen profession, cryobiology, if this became public knowledge.
{{cite magazine}}
: CS1 maint: url-status (link) - Clarke, Laurie (14 October 2022). "Why the sci-fi dream of cryonics never died". MIT Technology Review. Archived from the original on 14 October 2022. Retrieved 3 December 2024.
The Society for Cryobiology has even dropped its past cryonics-related restrictions.
- ^ "Position Statement - Cryonics" (PDF). Society for Cryobiology. November 2018. Archived (PDF) from the original on 1 April 2019. Retrieved 18 July 2019.
The Society recognizes and respects the freedom of individuals to hold and express their own opinions and to act, within lawful limits, according to their beliefs. Preferences regarding disposition of postmortem human bodies or brains are clearly a matter of personal choice and, therefore, inappropriate subjects of Society policy. The Society does, however, take the position that the knowledge necessary for the revival of live or dead whole mammals following cryopreservation does not currently exist and can come only from conscientious and patient research in cryobiology and medicine. In short, the act of preserving a body, head or brain after clinical death and storing it indefinitely on the chance that some future generation may restore it to life is an act of speculation or hope, not science, and as such is outside the purview of the Society for Cryobiology.
- Luhn, Alex (11 November 2017). "'Insurance' against death: Russian cryonics firm plans Swiss lab for people in pursuit of eternal life". Daily Telegraph. Archived from the original on 28 July 2019. Retrieved 28 July 2019.
- Jerry Adler (May 2015). "The Quest to Upload Your Mind into the Digital Space". Smithsonian Magazine. Archived from the original on 3 March 2016. Retrieved 21 February 2016.
- "Brain Freeze: Can putting faith in cryonics deliver life after death?". Toronto Sun. 6 October 2015. Archived from the original on 12 March 2016. Retrieved 21 February 2016.
- Dein S (2022). "Cryonics: Science or Religion". Journal of Religion & Health. 61 (4): 3164–3176. doi:10.1007/s10943-020-01166-6. PMID 33523374. S2CID 231745500.
- Kaiser S, Gross D, Lohmeier J, Rosentreter M, Raschke J (2014). "Attitudes and acceptance toward the technology of cryonics in Germany". International Journal of Technology Assessment in Health Care. 5 (1): 1–7. doi:10.1017/S0266462313000718. PMID 24499638. S2CID 41185307.
- McPheeters, Sam (May 2010). "Home Cryonics in the Smirk Age". The Corpse. ViceLand.com. Archived from the original on 17 July 2011. Retrieved 11 January 2020.
- "Leukemia claims son of Hall of Famer". ESPN.com. 7 March 2004. Archived from the original on 5 January 2016. Retrieved 18 February 2016.
- Steve Chawkins (4 December 2014). "L. Stephen Coles dies at 73; studied extreme aging in humans". Los Angeles Times. Archived from the original on 27 December 2017. Retrieved 17 April 2020.
- Greenberg, Andy (29 August 2014). "Bitcoin's Earliest Adopter Is Cryonically Freezing His Body to See the Future". WIRED. Archived from the original on 3 August 2018. Retrieved 6 March 2017.
- Thiel, Peter (16 September 2014). Zero to One: Notes on Startups, or How to Build the Future. Crown Business. p. 1 (chapter 14). ISBN 978-0-8041-3929-8.
- Brown, Mick (19 September 2014). "Peter Thiel: the billionaire tech entrepreneur on a mission to cheat death". The Telegraph. Archived from the original on 18 October 2014. Retrieved 16 October 2014.
- Pearce, David. "Quora Answers 2015 – 2022 by David Pearce". The Hedonistic Imperative. Archived from the original on 16 January 2022.
- "Was Larry King Cryogenically Frozen After his Death?". Inside Edition. 27 January 2021. Retrieved 30 January 2021.
- Leibovich M (26 August 2015). "Larry King Is Preparing for the Final Cancellation". New York Times. Archived from the original on 6 December 2019. Retrieved 14 February 2020.
- Stewart JB, Goldstein M, Silver-Greenberg J (31 July 2019). "Jeffrey Epstein Hoped to Seed Human Race With His DNA". The New York Times. Archived from the original on 31 July 2019. Retrieved 3 November 2019.
- Croucher S (1 August 2019). "Jeffrey Epstein Wanted to Freeze His Head and Penis After Dying: Report". Newsweek. Archived from the original on 31 October 2019. Retrieved 3 November 2019.
- Mikkelson, David (19 October 1995). "FACT CHECK: Was Walt Disney Frozen?". Snopes. Archived from the original on 23 January 2021. Retrieved 21 January 2019.
- Conradt, Stacy (15 December 2013). "Disney on Ice: The Truth About Walt Disney and Cryogenics". Mental Floss. Archived from the original on 10 January 2019. Retrieved 21 January 2019.
- The New York Times, "A Final Turn-On Lifts Timothy Leary Off" by Marlise Simons, 22 April 1997
Further reading
- "Mistakes Were Made". This American Life. Episode 354. 18 April 2008. The Public Radio Exchange (PRX). WBEZ Chicago. Transcript.
External links
Cryonics | |
---|---|
Organizations | |
Concepts | |
People | |
Related topics |
Pseudoscience | |||||||||
---|---|---|---|---|---|---|---|---|---|
List of topics characterized as pseudoscience | |||||||||
Terminology | |||||||||
Topics characterized as pseudoscience |
| ||||||||
Promoters of pseudoscience |
| ||||||||
Related topics | |||||||||
Resources |
|