Neuronal Alpha-Synuclein Disease: Difference between revisions

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⚫	'''Neuronal Alpha-Synuclein Disease''' is a proposed new combined definition of ] and ] based on <ref>{{Cite web \|title=Major Shift in the Clinical Definition of PD Triggers Debate \|url=https://www.medscape.com/viewarticle/major-shift-clinical-definition-parkinsons-triggers-debate-2024a1000cv1?form=fpf \|access-date=2024-12-26 \|website=Medscape \|language=en}}</ref><ref>{{cite web\|url=https://www.medpagetoday.com/neurology/parkinsonsdisease/108446\|title=New Parkinson's Definition Proposed Based on Biomarkers\|date=January 26, 2024}}</ref><ref>{{Cite journal \|last=Simuni \|first=Tanya \|last2=Chahine \|first2=Lana M \|last3=Poston \|first3=Kathleen \|last4=Brumm \|first4=Michael \|last5=Buracchio \|first5=Teresa \|last6=Campbell \|first6=Michelle \|last7=Chowdhury \|first7=Sohini \|last8=Coffey \|first8=Christopher \|last9=Concha-Marambio \|first9=Luis \|last10=Dam \|first10=Tien \|last11=DiBiaso \|first11=Peter \|last12=Foroud \|first12=Tatiana \|last13=Frasier \|first13=Mark \|last14=Gochanour \|first14=Caroline \|last15=Jennings \|first15=Danna \|date=2024-02-01 \|title=A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research \|url=https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00405-2/fulltext \|journal=The Lancet Neurology \|language=English \|volume=23 \|issue=2 \|pages=178–190 \|doi=10.1016/S1474-4422(23)00405-2 \|issn=1474-4422 \|archive-url=http://web.archive.org/web/20240201122650/https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00405-2/fulltext \|archive-date=2024-02-01}}</ref><ref>{{Cite journal \|last=Pagano \|first=Gennaro \|last2=Dam \|first2=Tien \|last3=Kerchner \|first3=Geoffrey A. \|last4=Galpern \|first4=Wendy R. \|last5=Biagioni \|first5=Milton \|last6=Karan \|first6=Rajesh \|last7=Jennings \|first7=Danna \|last8=Peterschmitt \|first8=M. Judith \|last9=Nikolcheva \|first9=Tania \|last10=Brundin \|first10=Patrik \|date=2024-12-20 \|title=Biologically defined neuronal synuclein disease as a tool to advance drug development \|url=https://www.nature.com/articles/s41531-024-00845-5 \|journal=npj Parkinson's Disease \|language=en \|volume=10 \|issue=1 \|pages=1–3 \|doi=10.1038/s41531-024-00845-5 \|issn=2373-8057}}</ref>
			{{Short description\|Neurodegenerative disorder}}
		⚫	'''Neuronal Alpha-Synuclein Disease''' ('''NSD''') is a proposed new combined definition of ] and ] based on biology instead of ].<ref>{{Cite web \|title=Major Shift in the Clinical Definition of PD Triggers Debate \|url=https://www.medscape.com/viewarticle/major-shift-clinical-definition-parkinsons-triggers-debate-2024a1000cv1?form=fpf \|access-date=2024-12-26 \|website=Medscape \|language=en}}</ref><ref>{{cite web\|url=https://www.medpagetoday.com/neurology/parkinsonsdisease/108446\|title=New Parkinson's Definition Proposed Based on Biomarkers\|date=January 26, 2024}}</ref><ref>{{Cite journal \|last=Simuni \|first=Tanya \|last2=Chahine \|first2=Lana M \|last3=Poston \|first3=Kathleen \|last4=Brumm \|first4=Michael \|last5=Buracchio \|first5=Teresa \|last6=Campbell \|first6=Michelle \|last7=Chowdhury \|first7=Sohini \|last8=Coffey \|first8=Christopher \|last9=Concha-Marambio \|first9=Luis \|last10=Dam \|first10=Tien \|last11=DiBiaso \|first11=Peter \|last12=Foroud \|first12=Tatiana \|last13=Frasier \|first13=Mark \|last14=Gochanour \|first14=Caroline \|last15=Jennings \|first15=Danna \|date=2024-02-01 \|title=A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research \|url=https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00405-2/fulltext \|journal=The Lancet Neurology \|language=English \|volume=23 \|issue=2 \|pages=178–190 \|doi=10.1016/S1474-4422(23)00405-2 \|issn=1474-4422 \|archive-url=http://web.archive.org/web/20240201122650/https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00405-2/fulltext \|archive-date=2024-02-01}}</ref><ref>{{Cite journal \|last=Pagano \|first=Gennaro \|last2=Dam \|first2=Tien \|last3=Kerchner \|first3=Geoffrey A. \|last4=Galpern \|first4=Wendy R. \|last5=Biagioni \|first5=Milton \|last6=Karan \|first6=Rajesh \|last7=Jennings \|first7=Danna \|last8=Peterschmitt \|first8=M. Judith \|last9=Nikolcheva \|first9=Tania \|last10=Brundin \|first10=Patrik \|date=2024-12-20 \|title=Biologically defined neuronal synuclein disease as a tool to advance drug development \|url=https://www.nature.com/articles/s41531-024-00845-5 \|journal=npj Parkinson's Disease \|language=en \|volume=10 \|issue=1 \|pages=1–3 \|doi=10.1038/s41531-024-00845-5 \|issn=2373-8057}}</ref>

			== References ==
			<references />

			]
			]

			{{nervoussystem-disease-stub}}

Latest revision as of 13:26, 27 December 2024

Neurodegenerative disorder

Neuronal Alpha-Synuclein Disease (NSD) is a proposed new combined definition of Parkinson's disease and Dementia with Lewy bodies based on biology instead of symptomatology.

References

"Major Shift in the Clinical Definition of PD Triggers Debate". Medscape. Retrieved 2024-12-26.
"New Parkinson's Definition Proposed Based on Biomarkers". January 26, 2024.
Simuni, Tanya; Chahine, Lana M; Poston, Kathleen; Brumm, Michael; Buracchio, Teresa; Campbell, Michelle; Chowdhury, Sohini; Coffey, Christopher; Concha-Marambio, Luis; Dam, Tien; DiBiaso, Peter; Foroud, Tatiana; Frasier, Mark; Gochanour, Caroline; Jennings, Danna (2024-02-01). "A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research". The Lancet Neurology. 23 (2): 178–190. doi:10.1016/S1474-4422(23)00405-2. ISSN 1474-4422. Archived from the original on 2024-02-01.
Pagano, Gennaro; Dam, Tien; Kerchner, Geoffrey A.; Galpern, Wendy R.; Biagioni, Milton; Karan, Rajesh; Jennings, Danna; Peterschmitt, M. Judith; Nikolcheva, Tania; Brundin, Patrik (2024-12-20). "Biologically defined neuronal synuclein disease as a tool to advance drug development". npj Parkinson's Disease. 10 (1): 1–3. doi:10.1038/s41531-024-00845-5. ISSN 2373-8057.

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