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| {{Infobox_Disease | | |||
| Name = Complex partial seizure | | |||
| Image = | | |||
| Caption = | | |||
| DiseasesDB = | | |||
| ICD10 = {{ICD10|G|40|2|g|40}}| | |||
| ICD9 = {{ICD9|345.4}} | | |||
| ICDO = | | |||
| OMIM = | | |||
| MedlinePlus = 000699 | | |||
| eMedicineSubj = neuro | | |||
| eMedicineTopic = 74 | | |||
| MeshID = D017029 | | |||
| }} | |||
| {{R to section}} | |||
| A '''complex partial seizure''' is an ] ] that is limited to one ] and causes ] of ] or ].<ref>Trescher, William H., and Ronald P. Lescher 2000, p. 1748.</ref> | |||
| ==Presentation== | |||
| Complex partial seizures are often preceded by a ] ].<ref name="Trescher, William H. 1749">Trescher, William H., and Ronald P. Lescher 2000, p. 1749.</ref> The seizure aura is a ].<ref name="Trescher, William H. 1749"/> The seizure ] might occur as a feeling of ], ], fear, ], or ].<ref name="Murro, Anthony M. 2006">Murro, Anthony M. 2006.</ref> The seizure ] might occur as a visual disturbance, such as ] or a change in the size of objects (] or ]).<ref> Engelsen, B A., C Tzoulis, B Karlsen, A Lillebø, L M 2008.</ref> Once consciousness is impaired, the person may display ]s such as lip smacking, chewing, or swallowing.<ref name="Murro, Anthony M. 2006"/> There may also be loss of memory (]) surrounding the seizure event.<ref name="Trescher, William H. 1749"/> The person may still be able to perform routine tasks such as walking or shopping. Witnesses may not recognize that anything is wrong. | |||
| Complex partial seizures might arise from any ] of the brain.<ref name="Trescher, William H. 1749"/> Complex partial seizures most commonly arise from the ] ], particularly the ], ] and ] regions.<ref>Trescher, William H., and Ronald P. Lescher 2000, p. 1750.</ref> A common associated brain abnormality is ].<ref name="Murro, Anthony M. 2006"/> Mesial temporal sclerosis is a specific pattern of hippocampal neuronal loss accompanied by hippocampal gliosis and atrophy.<ref>Trepeta, Scott 2007.</ref> Complex partial seizures occur when excessive and synchronous electrical brain activity causes impaired awareness and responsiveness.<ref>"International League Against Epilepsy." 2008.</ref> The abnormal electrical activity might spread to the rest of the brain and cause a secondary generalized ].<ref>Trescher, William H., and Ronald P. Lescher 2000, p. 1747.</ref> | |||
| == Creativity & Epilepsy == | |||
| Some observations suggest that complex partial seizures might enhance creativity.<ref>Natalie Angier: . ], October 12, 1993.</ref> However, research studies have generated conflicting results. In 2002, researchers at the Guelhane Military Medical Academy in Turkey evaluated thirty men with epilepsy and thirty-six men without. The men were instructed to use fragmented parts of a drawing to create a picture of their own. Those with complex partial seizures scored higher than their counterparts.<ref>E. Togrol, A. Togrol, S. Can: . ], 2002.</ref> A 2004 study suggested that temporal lobe epilepsy was not associated with their measure of creativity.<ref></ref> | |||
| ==Complex partial seizures and religious hallucinations== | |||
| Though her supporters disagree, the founder of the ], ]'s visions of God may have been caused by partial seizures. She had previously lost consciousness from a head injury.<ref> </ref> Her brain injury was significant enough to prevent her return to school. | |||
| ==See also== | |||
| * ] | |||
| == Notes == | |||
| {{reflist}} | |||
| ==References== | |||
| * Engelsen, B A., C Tzoulis, B Karlsen, A Lillebø, L M. Laegreid, J Aasly, M Zeviani, and L A. Bindoff. "POLG1 Mutations Cause a Syndromic Epilepsy with Occipital Lobe Predilection." Brain 131 (2008): 818-828. | |||
| * "International League Against Epilepsy." 2008. International League Against Epilepsy. Accessed 9 Apr. 2008 <http://www.ilae-epilepsy.org/>. | |||
| * Murro, Anthony M. "eMedicine - Complex Partial Seizures." 11 Oct. 2006. Medical College of Georgia. Accessed 9 Apr. 2008 <http://www.emedicine.com/neuro/topic74.htm>. | |||
| * Natalie Angier: . ], October 12, 1993. | |||
| * Togrol E., Togrol A., S. Can: . ], 2002. | |||
| * Trepeta, Scott. "eMedicine - Mesial Temporal Sclerosis." 11 Sept. 2007. Jamaica Hospital. Accessed 9 Apr. 2008 <http://www.emedicine.com/radio/topic443.htm>. | |||
| * Trescher, William H., and Ronald P. Lescher. "The Epilepsies." Neurology in Clinical Practice. Ed. Walter G. Bradley, Robert B. Daroff, Gerald M. Fenichel, and C. David Marsden. Boston: Butterworth-Heinemann, 2000. 1745-1780. | |||
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| * | |||
| * | |||
| {{Seizures and epilepsy}} | |||
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