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Ebola was a good articles nominee, but did not meet the good article criteria at the time. There may be suggestions below for improving the article. Once these issues have been addressed, the article can be renominated. Editors may also seek a reassessment of the decision if they believe there was a mistake.

Article milestones Date Process Result August 7, 2004 Featured article candidate Not promoted August 4, 2006 Good article nominee Not listed News items involving this article were featured on Misplaced Pages's Main Page in the "In the news" column on May 30, 2010, and August 5, 2012. Facts from this article were featured on Misplaced Pages's Main Page in the "On this day..." column on June 27, 2020, and June 27, 2022. Current status: Former good article nominee

This  level-4 vital article is rated B-class on Misplaced Pages's content assessment scale. It is of interest to multiple WikiProjects.

Africa Top‑importance This article is within the scope of WikiProject Africa, a collaborative effort to improve the coverage of Africa on Misplaced Pages. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.AfricaWikipedia:WikiProject AfricaTemplate:WikiProject AfricaAfrica Top This article has been rated as Top-importance on the project's importance scale. Medicine: Translation High‑importance This article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Misplaced Pages talk:WikiProject Medicine.MedicineWikipedia:WikiProject MedicineTemplate:WikiProject Medicinemedicine High This article has been rated as High-importance on the project's importance scale. This article is supported by the Translation task force (assessed as High-importance). Viruses Top‑importance This article is within the scope of WikiProject Viruses, a collaborative effort to improve the coverage of viruses on Misplaced Pages. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.VirusesWikipedia:WikiProject VirusesTemplate:WikiProject Virusesvirus Top This article has been rated as Top-importance on the project's importance scale.

This article has been mentioned by multiple media organizations: Noam Cohen (26 October 2014). "Misplaced Pages Is Emerging as Trusted Internet Source for Information on Ebola". The New York Times. But amid the fear mongering are several influential sites that are sticking to the facts about Ebola. Millions have come to rely on these sites, including those run by the Centers for Disease Control and Prevention, the World Health Organization and Misplaced Pages. Jessi Turnure (3 October 2014). "Study: Most Misplaced Pages articles about medical conditions contain errors". KAIT. I Google Ebola and the second one is Misplaced Pages," he said. "That's the first one people click on because they think, 'Well, it's the easiest and maybe it's the best.'" But Dr. Speights said that's wrong. He noticed errors early on in the Misplaced Pages article on Ebola. "They ited the New York Times Magazine. We don't do that. Dewey, Caitlin (November 5, 2015). "The most fascinating Misplaced Pages articles you haven't read". Washington Post. Earlier this year when the Ebola epidemic was on the rise, a group of volunteers, a few of them medical professionals, came together with the goal of making Misplaced Pages a trustworthy resource about Ebola.

Ideal sources for Misplaced Pages's health content are defined in the guideline Misplaced Pages:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Ebola. PubMed provides review articles from the past five years (limit to free review articles) The TRIP database provides clinical publications about evidence-based medicine. Other potential sources include: Centre for Reviews and Dissemination and CDC

On 30 May 2010, Ebola was linked from Slashdot, a high-traffic website. (Traffic) All prior and subsequent edits to the article are noted in its revision history.

This article is substantially duplicated by a piece in an external publication. Since the external publication copied Misplaced Pages rather than the reverse, please do not flag this article as a copyright violation of the following source: G. Lloyd (2011), Oxford Textbook of Zoonoses: Biology, Clinical Practice, and Public Health Control, Oxford University Press Additional comments The entire natural reservoir section http://books.google.ca/books?id=S90mOwgdz9kC&pg=PA364 is the same as our article from 2010 https://en.wikipedia.org/search/?title=Ebola_virus_disease&oldid=404199575#Natural_reservoirs

This article is substantially duplicated by a piece in an external publication. Since the external publication copied Misplaced Pages rather than the reverse, please do not flag this article as a copyright violation of the following source: Siram and Prasad (2014), An overview on Ebola virus disease (EVD) or Ebola hemorrhagic fever (EHF), International Journal of Allied Medical Sciences and Clinical Research Additional comments The article is nearly all copied and pasted http://ijamscr.com/sites/default/files/articles/IJAMSCR-14-401%20sriram.pdf

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This article has been viewed enough times in a single week to appear in the Top 25 Report 14 times. The weeks in which this happened: July 27 to August 2, 2014 (1st) August 3 to 9, 2014 (1st) August 10 to 16, 2014 (6th) August 17 to 23, 2014 (4th) August 24 to 30, 2014 (7th) August 31 to September 6, 2014 (18th) September 14 to 20, 2014 (18th) September 28 to October 4, 2014 (1st) October 5 to 11, 2014 (1st) October 12 to 18, 2014 (1st) October 19 to 25, 2014 (1st) October 26 to November 1, 2014 (5th) November 2 to 8, 2014 (15th) November 16 to 22, 2014 (24th)

Wiki Education Foundation-supported course assignment

This article was the subject of a Wiki Education Foundation-supported course assignment, between 18 August 2020 and 4 December 2020. Further details are available on the course page. Student editor(s): Aced 24.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 20:01, 16 January 2022 (UTC)

Ebola virus link to T-cell depletion

This edit request has been answered. Set the |answered= or |ans= parameter to no to reactivate your request.

Could someone, please, insert the following text into the main article?

A new study done at University of Texas Medical Branch at Galveston sheds new ligh on the way the Ebola virus attacks immune system of the infected person by disabling T cells.

In the said study, it has been demonstrated "that both viral mRNAs and antigens are detectable in CD4+ T cells despite the absence of productive infection. A protein phosphatase 1 inhibitor, 1E7-03, and siRNA-mediated suppression of viral antigens were used to demonstrate de novo synthesis of viral RNAs and antigens in CD4+ T cells, respectively. Cell-to-cell fusion of permissive Huh7 cells with non-permissive Jurkat T cells impaired productive EBOV infection suggesting the presence of a cellular restriction factor." It was "determined that viral transcription is partially impaired in the fusion T cells" and "that exposure of T cells to EBOV resulted in autophagy through activation of ER-stress related pathways. These data indicate that exposure of T cells to EBOV results in an abortive infection, which likely contributes to the lymphopenia observed during EBOV infections."

The above quotes come from:

Patrick Younan, Rodrigo I. Santos, Palaniappan Ramanathan, Mathieu Iampietro, Andrew Nishida, Mukta Dutta, Tatiana Ammosova, Michelle Meyer, Michael G. Katze, Vsevolod L. Popov, Sergei Nekhai, Alexander Bukreyev. Ebola virus-mediated T-lymphocyte depletion is the result of an abortive infection. PLOS Pathogens, 2019; 15 (10): e1008068 DOI: 10.1371/journal.ppat.1008068 — Preceding unsigned comment added by 172.88.197.74 (talk) 16:07, 27 February 2021 (UTC)

 Not done. We much prefer a secondary source for medical articles (see WP:MEDRS). Also, you need to simplify that down into layman terms, aka defining what all of those acronyms mean. ◢  Ganbaruby!  (Say hi!) 01:47, 9 March 2021 (UTC)

Semi-protected edit request on 13 June 2022

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The paragraph directly under the Causes section of the article states that "EVD in humans is caused by four of five viruses of the genus Ebolavirus," and goes on to talk about each of these five variants. The Misplaced Pages article for Ebolavirus, however, states that there are six different species of in the Genus Ebolavirus, with the addition of Bombali Ebola virus to the five mentioned in the paragraph. All sources used in this paragraph were published prior to this species identification in 2018, and as such would not have listed this species. As such I believe that this section should be updated to include this new species. A suggestion for possible edits (without updated references) to this section is below:

Cause

EVD in humans is caused by four of six viruses of the genus Ebolavirus. The four are Bundibugyo virus (BDBV), Sudan virus (SUDV), Taï Forest virus (TAFV) and one simply called Ebola virus (EBOV, formerly Zaire Ebola virus). EBOV, species Zaire ebolavirus, is the most dangerous of the known EVD-causing viruses, and is responsible for the largest number of outbreaks. The other two viruses, Reston virus (RESTV) and Bombali ebolavirus (BOMV), are not known to cause disease in humans, but have caused disease in other primates. All six viruses are closely related to marburgviruses.

FATCullen (talk) 04:16, 13 June 2022 (UTC)

 Done Aaron Liu (talk) 03:57, 8 July 2022 (UTC)

References

1. ^ Cite error: The named reference Hoenen2012 was invoked but never defined (see the help page).
2. Kuhn JH, Becker S, Ebihara H, Geisbert TW, Johnson KM, Kawaoka Y, et al. (December 2010). "Proposal for a revised taxonomy of the family Filoviridae: Classification, names of taxa and viruses, and virus abbreviations". Archives of Virology. 155 (12): 2083–103. doi:10.1007/s00705-010-0814-x. PMC 3074192. PMID 21046175.
3. Spickler, Anna. "Ebolavirus and Marburgvirus Infections" (PDF). Archived (PDF) from the original on 30 April 2015.
4. "About Ebola Virus Disease". Centers for Disease Control and Prevention (CDC). Archived from the original on 16 October 2014. Retrieved 18 October 2014.

Semi-protected edit request on 3 September 2022

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Add a record for the August 22, 2022 Ebola outbreak.

The National Institute for Biomedical Research (INRB) of the Democratic Republic of the Congo (DRC) announced on August 22, 2022, that a fresh Ebola virus case had been identified in the city of Beni, a town located in North Kivu. According to a statement from Placide Mbala, head of the Pathogen Genomics Laboratory at the National Institute for Biomedical Research (INRB), testing revealed that the case was genetically connected to the outbreak that occurred in the 2018–2020 academic year in the North Kivu and Ituri provinces and claimed approximately 2,300 lives (Ebola Zaire strain). Sequencing carried out at the Rodolphe Mérieux Laboratory of INRB in Goma confirmed the genetic link and thus determined it was not a new spillover event.

• National Road No. 2 is the main road in Beni

Placide Mbala also stated, "Our initial findings indicate that this case likely represents a new flare-up of the 2018-2020 North Kivu/Ituri outbreak, initiated by transmission of Ebola virus from a persistently infected survivor or a survivor who experienced a relapsed." Investigations are ongoing to determine the source. According to the statement, at least 131 contacts have been found, including 60 front-line healthcare providers, 59 of whom have received the Ebola vaccine. However, the WHO reports that A total of 134 hospital contacts (60 health care personnel and 74 co-patients) were been identified.

The test was administered using reverse transcription polymerase chain reaction (RT-PCR) testing on oropharyngeal secretions and sent to National Institute for Biomedical Research, Beni, which revealed a positive result. The sample was analyzed at the Rodolphe Mérieux INRB Laboratory in Goma for quality control purposes, and on August 16, 2022, RT-PCR results were confirmed. The body was given to the family before the test findings were known, and it was then buried on August 16, 2022.

The WHO sent supporting health officials to investigate the case and prepare for a possible outbreak during the ongoing analysis. They worked with local health authorities to start contact tracing, ensuring proper infection prevention and control measures were in place. They also started an Ebola awareness campaign in the area. The WHO also stated that "the current resurgence is not unexpected given that EVD is endemic in the country and Ebola virus is present in animal reservoirs in the region."

The re-emergence of Ebola is a significant public health concern in the Democratic Republic of the Congo, and there are still gaps in the country's capacity to recover, prepare and respond to outbreaks. The outbreaks in the country unrelated to the August 2022 Ebola outbreak (COVID-19, cholera, measles, polio, yellow fever, monkeypox, etc), as well as other humanitarian factors (armed groups, refusal of outbreak control measures, etc), have strained the Beni health system and its resources.

The WHO described the national risk as high; however, the regional and global levels were assessed as moderate to low, respectively.

Isacc Barker (talk) 19:46, 3 September 2022 (UTC)

References

1. ^ "The Democratic Republic of the Congo investigates suspected Ebola case in North Kivu". World Health Organisation. Retrieved 3 September 2022.
2. ^ "Ebola virus disease - Democratic Republic of the Congo". World Heath Organisation. Retrieved 3 September 2022.

 Not done for now: This is written like a news article. Please see WP:NOTNEWS and reopen your request after you have refactored it. Aaron Liu (talk) 11:41, 15 September 2022 (UTC)

Wiki Education assignment: Plagues and People

This article was the subject of a Wiki Education Foundation-supported course assignment, between 22 August 2023 and 11 December 2023. Further details are available on the course page. Student editor(s): Bridgettemora (article contribs). Peer reviewers: Shy.Mancha13, BrightBuds.

— Assignment last updated by Maxwellmcgowan (talk) 20:37, 26 October 2023 (UTC)

Semi-protected edit request on 27 September 2024

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This edit suggestion is simply to change some of the wording in the "Cause" paragraph. It seems that when the paragraph was updated to include the sixth identified strain of Ebolavirus (Bombali virus, or BOMV) some of the wording was not updated. The final sentence of the paragraph is:

All five viruses are closely related to marburgviruses.

It should be updated to:

All six viruses are closely related to marburgviruses. FATCullen (talk) 21:18, 27 September 2024 (UTC)

 Done PianoDan (talk) 21:35, 27 September 2024 (UTC)

1. ^ Cite error: The named reference Hoenen2012 was invoked but never defined (see the help page).

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