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{{Infobox Disease |
Name = Complex partial seizure |
Image = |
Caption = |
DiseasesDB = |
ICD10 = {{ICD10|G|40|2|g|40}}|
ICD9 = {{ICD9|345.4}} |
ICDO = |
OMIM = |
MedlinePlus = 000699 |
eMedicineSubj = neuro |
eMedicineTopic = 74 |
MeshID = D017029 |
}}


{{R to section}}
A '''complex partial seizure''' is an ] ] that is associated with bilateral ] involvement and causes ] of ] or ], i.e. loss of consciousness.<ref>Trescher, William H., and Ronald P. Lescher 2000, p. 1748.</ref>

==Presentation==
Complex partial seizures are often preceded by a ] ].<ref name="Trescher, William H. 1749">Trescher, William H., and Ronald P. Lescher 2000, p. 1749.</ref> The seizure aura is a ].<ref name="Trescher, William H. 1749"/> The ] may manifest itself as a feeling of ], ], fear, ], or ].<ref name="Murro, Anthony M. 2006">Murro, Anthony M. 2006.</ref> The seizure ] might also occur as a visual disturbance, such as ] or a change in the size of objects (] or ]).<ref>Engelsen, B A., C Tzoulis, B Karlsen, A Lillebø, L M 2008.</ref> Once consciousness is impaired, the person may display ]s such as lip smacking, chewing, or swallowing.<ref name="Murro, Anthony M. 2006"/> There may also be loss of memory (]) surrounding the seizure event.<ref name="Trescher, William H. 1749"/> The person may still be able to perform routine tasks such as walking. Witnesses may not recognize that anything is wrong.

Complex partial seizures might arise from any ] of the brain.<ref name="Trescher, William H. 1749"/> Complex partial seizures most commonly arise from the ] ], particularly the ], ] and ] regions.<ref>Trescher, William H., and Ronald P. Lescher 2000, p. 1750.</ref> A common associated brain abnormality is ].<ref name="Murro, Anthony M. 2006"/> Mesial temporal sclerosis is a specific pattern of hippocampal neuronal loss accompanied by hippocampal gliosis and atrophy.<ref>Trepeta, Scott 2007.</ref> Complex partial seizures occur when excessive and synchronous electrical brain activity causes impaired awareness and responsiveness.<ref>"International League Against Epilepsy." 2008.</ref> The abnormal electrical activity might spread to the rest of the brain and cause a secondary generalized ].<ref>Trescher, William H., and Ronald P. Lescher 2000, p. 1747.</ref>

==See also==
* ]

== Notes ==
{{reflist}}

==References==
* "International League Against Epilepsy." 2008. International League Against Epilepsy. Accessed 9 Apr. 2008 <http://www.ilae-epilepsy.org/>.
* Murro, Anthony M. "eMedicine - Complex Partial Seizures." 11 Oct. 2006. Medical College of Georgia. Accessed 9 Apr. 2008 <http://www.emedicine.com/neuro/topic74.htm>.
* Trepeta, Scott. "eMedicine - Mesial Temporal Sclerosis." 11 Sept. 2007. Jamaica Hospital. Accessed 9 Apr. 2008 <http://www.emedicine.com/radio/topic443.htm>.
* Trescher, William H., and Ronald P. Lescher. "The Epilepsies." Neurology in Clinical Practice. Ed. Walter G. Bradley, Robert B. Daroff, Gerald M. Fenichel, and C. David Marsden. Boston: Butterworth-Heinemann, 2000. 1745-1780.

{{Seizures and epilepsy}}

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