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Revision as of 19:22, 1 September 2011 editBogBot (talk | contribs)Bots53,132 edits populated new fields in {{drugbox}} and reordered per bot approval. Report errors and suggestions to User_talk:BogBot← Previous edit Latest revision as of 22:50, 6 April 2023 edit undoEntranced98 (talk | contribs)Extended confirmed users, Pending changes reviewers, Rollbackers170,249 edits Importing Wikidata short description: "Chemical compound"Tag: Shortdesc helper 
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{{Short description|Chemical compound}}
{{Drugbox {{Drugbox
| Verifiedfields = changed | Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 376090672 | verifiedrevid = 448828501
| IUPAC_name = (3''S'',5''S'',8''R'',10''S'',13''R'',14''S'',17''R'')-5,14-dihydroxy-3-((2''R'',4''S'',5''S'',6''R'')-5-hydroxy-4-methoxy-6-methyltetrahydro-2''H''-pyran-2-yloxy)-13-methyl-17-(5-oxo-2,5-dihydrofuran-3-yl)hexadecahydro-1''H''-cyclopentaphenanthrene-10-carbaldehyde | IUPAC_name = (3''S'',5''S'',8''R'',10''S'',13''R'',14''S'',17''R'')-5,14-dihydroxy-3-((2''R'',4''S'',5''S'',6''R'')-5-hydroxy-4-methoxy-6-methyltetrahydro-2''H''-pyran-2-yloxy)-13-methyl-17-(5-oxo-2,5-dihydrofuran-3-yl)hexadecahydro-1''H''-cyclopentaphenanthrene-10-carbaldehyde
| image = Cymarine.png | image = Cymarine.png
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<!--Identifiers--> <!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|CAS}}
| CAS_number = 508-77-0 | CAS_number = 508-77-0
| ATC_prefix = C01 | ATC_prefix = C01
| ATC_suffix = AC03 | ATC_suffix = AC03
| PubChem = 10504 | PubChem = 441853
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 390429
| smiles = O=C\1OC/C(=C/1)2CC6(O)2(C)CC46CC5(O)C(O3O((O)(OC)C3)C)CC45C=O
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C30H44O9/c1-17-26(33)23(36-3)13-25(38-17)39-19-4-9-28(16-31)21-5-8-27(2)20(18-12-24(32)37-15-18)7-11-30(27,35)22(21)6-10-29(28,34)14-19/h12,16-17,19-23,25-26,33-35H,4-11,13-15H2,1-3H3/t17-,19+,20-,21+,22-,23+,25+,26-,27-,28+,29+,30+/m1/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = XQCGNURMLWFQJR-ZNDDOCHDSA-N
| DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| UNII_Ref = {{fdacite|changed|FDA}} | UNII_Ref = {{fdacite|correct|FDA}}
| UNII = UK3LS8435E | UNII = UK3LS8435E
| ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 1651908 | ChEMBL = 1651908


<!--Chemical data--> <!--Chemical data-->
| C=30 | H=44 | O=9 | C=30 | H=44 | O=9
| molecular_weight = 548.665 g/mol
| synonyms = Cymarine; K-Strophanthin-α; NSC 7522; Strophantin K; WV 90043a; k-Strophanthin-α | synonyms = Cymarine; K-Strophanthin-α; NSC 7522; Strophantin K; WV 90043a; k-Strophanthin-α
| melting_point = 148
}} }}


'''Cymarin''' (or '''cymarine''') is a ]. '']'' used as a source of fiber by ] and '']'' ({{zh|c=羅布麻}}) used as a ] in ] both contain cymarin.<ref>''Edible and Medicinal plants of the West'', Gregory L. Tilford, ISBN 0-87842-359-1</ref> Cymarin is a cardiogenic toxin that causes cardiac arrhythmia in humans.<ref>'']'', 12th Edition, '''2830'''</ref> Cymarin is used in modern medicine in formulated pharmaceutical preparations used to treat a variety of tumors.{{Citation needed|date=August 2011}} '''Cymarin''' (or '''cymarine''') is a ]. Plants of the genus '']'', including '']'' and '']'', contain cymarin.<ref>{{cite book | title = Edible and Medicinal plants of the West | vauthors = Tilford GL | isbn = 0-87842-359-1}}</ref> Cymarin is a cardiac glycoside and an anti-] and ] agent.<ref>{{PubChem|441853}}</ref>


== References == ==References==
{{reflist}} {{reflist}}

==External links==
*{{Commonscatinline}}


{{Cardiac glycosides}} {{Cardiac glycosides}}




] ]

Latest revision as of 22:50, 6 April 2023

Chemical compound Pharmaceutical compound
Cymarin
Clinical data
Other namesCymarine; K-Strophanthin-α; NSC 7522; Strophantin K; WV 90043a; k-Strophanthin-α
ATC code
Identifiers
IUPAC name
  • (3S,5S,8R,10S,13R,14S,17R)-5,14-dihydroxy-3-((2R,4S,5S,6R)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yloxy)-13-methyl-17-(5-oxo-2,5-dihydrofuran-3-yl)hexadecahydro-1H-cyclopentaphenanthrene-10-carbaldehyde
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.007.353 Edit this at Wikidata
Chemical and physical data
FormulaC30H44O9
Molar mass548.673 g·mol
3D model (JSmol)
Melting point148 °C (298 °F)
SMILES
  • O=C\1OC/C(=C/1)2CC6(O)2(C)CC46CC5(O)C(O3O((O)(OC)C3)C)CC45C=O
InChI
  • InChI=1S/C30H44O9/c1-17-26(33)23(36-3)13-25(38-17)39-19-4-9-28(16-31)21-5-8-27(2)20(18-12-24(32)37-15-18)7-11-30(27,35)22(21)6-10-29(28,34)14-19/h12,16-17,19-23,25-26,33-35H,4-11,13-15H2,1-3H3/t17-,19+,20-,21+,22-,23+,25+,26-,27-,28+,29+,30+/m1/s1
  • Key:XQCGNURMLWFQJR-ZNDDOCHDSA-N
  (what is this?)  (verify)

Cymarin (or cymarine) is a cardiac glycoside. Plants of the genus Apocynum, including Apocynum cannabinum and Apocynum venetum, contain cymarin. Cymarin is a cardiac glycoside and an anti-arrhythmia and cardiotonic agent.

References

  1. Tilford GL. Edible and Medicinal plants of the West. ISBN 0-87842-359-1.
  2. CID 441853 from PubChem

External links

  • Media related to Cymarin at Wikimedia Commons
Cardiac glycosides (C01A)
Bufadienolides
Bufo
Scilla
Kalanchoe
Cardenolides
Digitalis
Strophanthus
Thevetia


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