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{{Short description|Chemical compound}} |
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{{Drugbox |
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{{Drugbox |
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| Verifiedfields = changed |
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| verifiedrevid = 443501665 |
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| Watchedfields = changed |
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| verifiedrevid = 444443115 |
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| IUPAC_name = (''RS'')-''N''-(2-Oxothiolan-3-yl)acetamide |
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| IUPAC_name = (''RS'')-''N''-(2-Oxothiolan-3-yl)acetamide |
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| image = Citiolone.png |
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| image = Citiolone.png |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> |
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| legal_status = |
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| legal_status = |
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| routes_of_administration = |
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| routes_of_administration = |
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<!--Pharmacokinetic data--> |
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<!--Pharmacokinetic data--> |
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| metabolism = |
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| metabolism = |
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| elimination_half-life = |
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| elimination_half-life = |
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| excretion = |
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| excretion = |
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<!--Identifiers--> |
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<!--Identifiers--> |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| CAS_number = 1195-16-0 |
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| CAS_number = 1195-16-0 |
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| ATC_prefix = A05 |
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| ATC_prefix = A05 |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = |
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| DrugBank = |
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| ChEMBL_Ref = {{ebicite|changed|EBI}} |
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| ChEMBL = 2104457 |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 13864 |
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| ChemSpiderID = 13864 |
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<!--Chemical data--> |
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<!--Chemical data--> |
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| C=6 | H=9 | N=1 | O=2 | S=1 |
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| C=6 | H=9 | N=1 | O=2 | S=1 |
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| molecular_weight = 159.21 g/mol |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C6H9NO2S/c1-4(8)7-5-2-3-10-6(5)9/h5H,2-3H2,1H3,(H,7,8) |
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| StdInChI = 1S/C6H9NO2S/c1-4(8)7-5-2-3-10-6(5)9/h5H,2-3H2,1H3,(H,7,8) |
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}} |
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'''Citiolone''' is a drug used in liver therapy. It is a derivative of the ] ]. |
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'''Citiolone''' is a drug used in ] therapy. |
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It is a derivative of the ] ].<ref>{{cite journal | vauthors = de Barrio M, Tornero P, Prieto A, Sainza T, Zubeldia JM, Herrero T | title = Recurrent fixed drug eruption caused by citiolone | journal = Journal of Investigational Allergology & Clinical Immunology | volume = 7 | issue = 3 | pages = 193–194 | year = 1997 | pmid = 9252880 }}</ref> Citilone has also been studied with regards to ] due to it being a ] free radical scavenger. The drug has been shown to protect ] cells subjected to temperature conditions of 8-25 °C.<ref>{{cite journal | vauthors = Kruuv J, Glofcheski DJ | title = Further evidence for two modes of hypothermia damage | journal = Cryobiology | volume = 30 | issue = 3 | pages = 313–321 | date = June 1993 | pmid = 8370318 | doi = 10.1006/cryo.1993.1030 }}</ref> |
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== References == |
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{{reflist}} |
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{{Bile and liver therapy}} |
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{{Bile and liver therapy}} |
