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| {{Redirect|CE2|the French elementary school grade|Education in France}} | |||
| {{chembox | |||
| | Verifiedfields = changed | |||
| | verifiedrevid = 477003063 | |||
| | ImageFile = creatine ethyl ester.png | |||
| | ImageSize = | |||
| | IUPACName = Ethyl ''N''-(aminoiminomethyl)-''N''-methylglycine | |||
| | OtherNames = | |||
| | Section1 = {{Chembox Identifiers | |||
| | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | |||
| | ChemSpiderID = 8373317 | |||
| | InChI = 1/C6H13N3O2/c1-3-11-5(10)4-9(2)6(7)8/h3-4H2,1-2H3,(H3,7,8) | |||
| | InChIKey = UFUWQSYRGLMLKP-UHFFFAOYAK | |||
| | SMILES1 = O=C(OCC)CN(C(=)N)C | |||
| | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | |||
| | StdInChI = 1S/C6H13N3O2/c1-3-11-5(10)4-9(2)6(7)8/h3-4H2,1-2H3,(H3,7,8) | |||
| | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | |||
| | StdInChIKey = UFUWQSYRGLMLKP-UHFFFAOYSA-N | |||
| | CASNo_Ref = {{cascite|changed|??}} | |||
| | CASNo = 15366-29-7 | |||
| | PubChem = 10197817 | |||
| | SMILES = NC(N(C)CC(OCC)=O)=N | |||
| }} | |||
| | Section2 = {{Chembox Properties | |||
| | Formula = C<sub>6</sub>H<sub>13</sub>N<sub>3</sub>O<sub>2</sub> | |||
| | MolarMass = 159.19 g/mol | |||
| | Appearance = | |||
| | Density = | |||
| | MeltingPt = | |||
| | BoilingPt = | |||
| | Solubility = | |||
| | pKa = 2.67, 11.2, 6 | |||
| }} | |||
| | Section3 = {{Chembox Hazards | |||
| | MainHazards = | |||
| | FlashPt = | |||
| | Autoignition = | |||
| }} | |||
| }} | |||
| '''Creatine ethyl ester''', also known as '''creatine ester''', '''cre-ester''' and '''CEE''', is a substance sold as an aid for athletic performance and for muscle development in ]. It is an ] ] derivative of ], from which it is made. In the body, CEE is converted back into creatine.{{Citation needed|date=April 2010}} CEE is said to have a much better absorption rate and a longer ] in the body than regular ], because it is slightly more ].{{Citation needed|date=April 2010}} It is also proposed to bypass the creatine transporter, thereby increasing skeletal muscle uptake of creatine and leading to an increased ability to regenerate ATP.<ref name="Spillane2009">{{cite journal | doi = 10.1186/1550-2783-6-6 | pmc = 2649889 | title = The effects of creatine ethyl ester supplementation combined with heavy resistance training on body composition, muscle performance, and serum and muscle creatine levels | pmid = 19228401 | year = 2009 | last1 = Spillane | first1 = Mike | last2 = Schoch | first2 = Ryan | last3 = Cooke | first3 = Matt | last4 = Harvey | first4 = Travis | last5 = Greenwood | first5 = Mike | last6 = Kreider | first6 = Richard | last7 = Willoughby | first7 = Darryn S | journal = Journal of the International Society of Sports Nutrition | volume = 6 | pages = 6}}</ref> However, in a published study comparing the two, CEE was not as effective at increasing serum and muscle creatine levels or in improving body composition, muscle mass, strength, and power. | |||
| Research published in 2013 found that creatine ethyl ester is likely to be no better than taking creatine. This report should though be discredited, due to the fact that it only measured the amount of creatine produced by the body after consumption. It found that the levels of creatine found after consumption of CEE than taking standard creatine was the same. The report did not mention the benefits of CEE, it takes far lower doses to create those levels, absorbed quiker and lasts a lot longer than that of standard Creatine.<ref>{{cite journal|doi=10.1016/j.bbrc.2009.06.037|title=Non-enzymatic hydrolysis of creatine ethyl ester|year=2009|last1=Katseres|first1=Nicholas S.|last2=Reading|first2=David W.|last3=Shayya|first3=Luay|last4=Dicesare|first4=John C.|last5=Purser|first5=Gordon H.|journal=Biochemical and Biophysical Research Communications|volume=386|issue=2|pages=363–7|pmid=19524547}}</ref> <ref>{{cite news|publisher=University of Tulsa|title=Analysis of Creatine Ethyl Ester: TU researchers bust myth on popular nutritional supplement|url=http://www.utulsa.edu/academics/colleges/college-of-engineering-and-natural-sciences/departments-and-schools/Department-of-Chemistry-and-Biochemistry/Research/analysis-of-creatine-ethyl-ester.aspx}}</ref> | |||
| As a supplement, the compound was developed, patented and licensed through ], the technology transfer entity of the ], and is sold under numerous brand names. | |||
| ==See also== | |||
| * ] | |||
| ==References== | |||
| {{Reflist}} | |||
| ] | |||
| ] | |||
| ] | |||
Latest revision as of 14:02, 8 May 2018
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