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| '''Edward Lewis Tobinick''' is an American ] who is known for the study and promotion of ] as a potential ] treatment for ]. Tobinick trained in internal medicine and dermatology. Prior to his work with etanercept, Tobinick practiced dermatology and developed a laser hair removal technique. Tobinick offered etanercept therapy for back problems (in a treatment known as DiskCure) before promoting its use for other neurological conditions, including Alzheimer's disease, stroke and Parkinson's disease. An article in ] was written critical of his use of perispinal etanercept injections for these conditions. Author ] was subsequently sued by Tobinick in 2015 for that article. On September 30, 2015 the court found no merit in Tobinick's claim that Novella and SBM were profiting from criticism of perispinal etanercept and found in Novella's favor. | |||
| ==Early career== | |||
| Tobinick is an internist and dermatologist.<ref name=SBM2014>{{cite web|author1=Steven Novella|title=Another Lawsuit To Suppress Legitimate Criticism – This Time SBM|url=http://www.sciencebasedmedicine.org/tag/edward-tobinick/|website=]|accessdate=18 September 2014|date=July 23, 2014}}</ref><ref name=CaseWatch>{{cite web|title=Disciplinary Action against Edward Lewis Tobinick, M.D.|url=http://www.casewatch.org/board/med/tobinick/accusation.shtml|website=CaseWatch|accessdate=18 September 2014}}</ref> He previously ran a hair removal practice known as the Institute of Laser Medicine,<ref name=CaseWatch/><ref>{{cite web|title=Breakthrough or False Hope? Etanercept Case Report Draws Scrutiny|url=http://www.alzforum.org/news/research-news/breakthrough-or-false-hope-etanercept-case-report-draws-scrutiny|accessdate=18 September 2014|date=21 Jan 2008}}</ref> practiced dermatology in Beverly Hills and was the medical director of a skin cancer clinic.<ref name=Philly>{{cite news|last1=Lowe|first1=Jennifer|title=Warning: fry now, pay later|url=http://articles.philly.com/1987-05-20/entertainment/26165214_1_skin-cancer-screening-malignant-melanoma-squamous-cell-carcinomas|accessdate=September 19, 2014|work=]|date=May 20, 1987}}</ref> While at the Institute of Laser Medicine, Tobinick developed a hair removal technique known as photolysis.<ref name=Peace>{{cite news|last1=Glionna|first1=John|title=Hair Peace|url=http://articles.latimes.com/1998/aug/20/local/me-14841|accessdate=September 19, 2014|work=]|date=August 20, 1998}}</ref> | |||
| ==Work with etanercept== | |||
| Tobinick operates the Institute of Neurological Recovery. The neurological disorders he has claimed to treat with etanercept include: Alzheimer’s, stroke, traumatic brain injury, Parkinson’s disease, carpal tunnel syndrome, brain tumor, spinal cord injury, and back pain.<ref name=SBM2013/> These practices are controversial.<ref name=CaseWatch/> He referred to the treatment as DiskCure when he was focusing on its use for back pain. In 2002, he said that he did not create publicity for DiskCure because he already had patients from around the United States and did not want to end up with more patients than the clinic had the capacity to treat.<ref name=LAM>{{cite news|last1=McCarthy|first1=Jenna|title=Back in business|url=https://books.google.com/books?id=ZF0EAAAAMBAJ&pg=PA114|accessdate=September 19, 2014|work=]|date=March 2002}}</ref> | |||
| Explaining the treatment's effects on the brain, Tobinick says that after the medication is injected at the back of the neck and the patient is tilted backwards for a few minutes, the drug is able to reach the brain via the ].<ref name=Brochu>{{cite news|last1=Brochu|first1=Nicole|title=Boca doctor gives stroke survivors new shot at mobility, independence|url=http://articles.sun-sentinel.com/2012-12-08/health/fl-stroke-brain-injury-treatment-20121206_1_stroke-patients-boca-doctor-traumatic-brain-injury|accessdate=September 18, 2014|work=]|date=December 8, 2012}}</ref> He says that the drug works in Alzheimer's disease because of its action on a protein known as ].<ref name=Denver>{{cite web|title=Armed Against Alzheimer's: A Shot Of Controversy: Bogus Or Breakthrough?|url=http://www.thedenverchannel.com/lifestyle/health/armed-against-alzheimer-s-a-shot-of-controversy-bogus-or-breakthrough-|publisher=]|accessdate=September 19, 2014|date=February 2, 2009}}</ref> The manufacturer of the medication, ], specifically does not support its use in Alzheimer's disease.<ref>{{cite web|title=Amgen Statement on Alzheimer's Case Study|url=http://www.amgen.com/media/rapid_cognitive_improvement.html|website=Amgen|accessdate=18 September 2014}}</ref> | |||
| The same year, the ] placed Tobinick on probation for promoting the unapproved use of etanercept for back or neck pain before any scientific studies had been published on the subject. He completed the requirements they imposed on him in 2008 and is no longer on probation.<ref name=SBM2013>{{cite web|author1=Steven Novella|title=Enbrel for Stroke and Alzheimer’s|url=http://www.sciencebasedmedicine.org/enbrel-for-stroke-and-alzheimers/|website=Science Based Medicine|accessdate=18 September 2014|date=May 8, 2013}}</ref><ref>{{cite web|first2 = Sonya|last2 = Colberg|first3 = |last3 = |first4 = |last4 = |title = Oklahoma doctors question a California physician's treatment for strokes|url = http://newsok.com/oklahoma-doctors-question-a-california-physicians-treatment-for-strokes/article/3576689|date = 13 June 2011|publisher = The Oklahoman|website = newsok.com|accessdate = 2014-09-16}}</ref> | |||
| According to a 2012 article in the '']'', there is one physician in Australia who was trained in Tobinick's technique, but that physician would not allow the publication to disclose his identity.<ref name="SMH">{{cite web|last1=Robotham|first1=Julie|title=Searching for a light to dispel the darkness|url=http://www.smh.com.au/national/searching-for-a-light-to-dispel-the-darkness-20120817-24dpx.html|publisher=]|accessdate=September 19, 2014|date=August 18, 2012}}</ref> | |||
| A 2013 article in the '']'' said that Alan Waxman, the chief of nuclear medicine at ], had been willing to collaborate with Tobinick on a study that evaluated brain scans following etanercept injections for ]. The article said that the widower of a woman Tobinick had treated for five years before her 2011 death had been willing to pay the $60,000 required to fund the study. Tobinick refused to participate in the study. He cited scientific inadequacies of the proposed study and said that he wanted to study the drug in stroke patients instead.<ref name=Zarembo>{{cite news|last1=Zarembo|first1=Alan|title=A wife's Alzheimer's, a husband's obsession|url=http://www.latimes.com/science/la-me-chiate-20130505-dto-story.html#page=1|accessdate=September 18, 2014|work=]|date=May 5, 2013}}</ref> | |||
| An article in ] is critical of his use of perispinal etanercept injections for these conditions.<ref name=SBM2013/> It raises concerns over his patenting of a procedure which is viewed negatively in many areas of the world.<ref name=SBM2013/> It concludes that his research does not "establish the effectiveness" of this treatment.<ref name=SBM2013/> In 2014, Tobinick (along with two of his companies) sued ], the Society for Science Based Medicine, ] and ], Novella's employer, alleging that the blog post constituted an advertisement and that "in violation of the ], Novella has and continues to publish a false advertisement disparaging Plaintiffs entitled 'Enbrel for Stroke and Alzheimer's', ('the 'Advertisement') and implying that the INR plaintiffs' use of entanercept is ineffective and useless;" and "The Advertisement is extremely inflammatory and defamatory in nature as it contains multiple false and misleading statements of fact regarding Plaintiffs.".<ref name=SBM2014/> Yale University, SFSBM and SGU Productions were removed form the case through summary judgements, leaving only Novella as defendant. The suit in respect of one of the plaintiffs, Tobinick's California corporation, was then struck down under California's anti-] statute.<ref name="SfSBMUpdateJune10">{{cite web | url=https://www.sciencebasedmedicine.org/lawsuit-update/ | title=Lawsuit Update | publisher=Society for Science Based Medicine | date=June 10, 2015 | accessdate=October 12, 2015}}</ref> | |||
| Finally on September 30, 2015, United States District Judge Robin Rosenberg ordered the case closed and found in ] for Novella. Tobinick was unable to show that Novella had profited from his blog post or that it was in anyway an advertisement. "... It is hereby ORDERED and ADJUDGED that defendant Dr. Steven Novella ... is GRANTED. All pending motions are DENIED AS MOOT, all deadlines are TERMINATED, and the Clerk of Court is directed to CLOSE THE CASE.<ref>{{cite web|last1=Cushing|first1=Tim|title=Court Hands Loss To Doctor Who Sued Over Blog Posts Criticizing His Questionable Alzheimer's Treatments|url=https://www.techdirt.com/articles/20151002/09381332425/court-hands-loss-to-doctor-who-sued-over-blog-posts-criticizing-his-questionable-alzheimers-treatments.shtml|website=Tech Dirt|accessdate=6 October 2015}}</ref><ref>{{Cite web|title = Tobinick Lawsuit Update – Justice Has Prevailed |url = https://www.sciencebasedmedicine.org/tobinick-lawsuit-update-justice-has-prevailed/|website = ]|accessdate = 2015-10-06}}</ref> | |||
| ==References== | |||
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