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| {{Short description|German chemist (1828–1890)}} | |||
| {{Infobox scientist | {{Infobox scientist | ||
| |name = Friedrich Gaedcke | | name = Friedrich Gaedcke | ||
| |image = |
| image = | ||
| |image_size = 150px | | image_size = 150px | ||
| |caption = Friedrich Gaedcke | | caption = Friedrich Gaedcke | ||
| |birth_date = 5 June 1828 | | birth_date = 5 June 1828 | ||
| |birth_place = | | birth_place = | ||
| |death_date = {{ |
| death_date = {{death-date and age|19 September 1890|5 June 1828}} | ||
| |death_place = | | death_place = | ||
| | |
| nationality = ] | ||
| | |
| ethnicity = | ||
| | |
| field = pharmaceutics | ||
| ⚫ | | work_institutions = | ||
| |field = pharmaceutics | |||
| ⚫ | | alma_mater = | ||
| ⚫ | |work_institutions = | ||
| ⚫ | | doctoral_advisor = | ||
| ⚫ | |alma_mater = | ||
| ⚫ | | doctoral_students = | ||
| ⚫ | |doctoral_advisor = | ||
| ⚫ | | known_for = discovering cocaine | ||
| ⚫ | |doctoral_students = | ||
| ⚫ | | author_abbrev_bot = | ||
| ⚫ | |known_for = discovering cocaine |
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| ⚫ | | author_abbrev_zoo = | ||
| ⚫ | |author_abbrev_bot = | ||
| ⚫ | | prizes = | ||
| ⚫ | |author_abbrev_zoo = | ||
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| religion = | ||
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| footnotes = | ||
| ⚫ | | |
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| }} | }} | ||
| '''Friedrich Georg Carl (Friedrich) Gaedcke''' (5 June 1828 – 19 September 1890) was a German chemist.<ref name="NIH">{{cite web |url=https://pubmed.ncbi.nlm.nih.gov/13395966/ |title= |publisher=PubMed |access-date=30 June 2024}}</ref> He was the first person to isolate the ] ] in 1855.<ref name="j240">{{cite book | last=Luch | first=Andreas | title=Molecular, Clinical and Environmental Toxicology | publisher=Springer Science & Business Media | publication-place=Basel Boston | date=2009-04-03 | isbn=978-3-7643-8336-7 | page=20}}</ref><ref name="West">{{cite book | last=West | first=Krista | title=Cocaine and Crack | publisher=Infobase Publishing | date=2008 | isbn=978-1-4381-1822-2 | page=47}}</ref> | |||
| '''Friedrich Georg Carl (Friedrich) Gaedcke''' (5 June 1828 – 19 September 1890) was a German chemist. He was the first person to isolate the ] ] which happened in 1855. | |||
| ==Life== | |||
| ⚫ | Gaedcke named the alkaloid “erythroxyline,” and published a description in the journal ].<ref>{{cite journal | ||
| ⚫ | Gaedcke worked in a pharmacy in ] and studied in Rostock between 1850 and 1851. In 1856, he took over a pharmacy in ] which he ran for 34 years. He is described as having made contributions to the pharmaceutical history of ]<ref name="NIH"/> | ||
| ===Discovery of Cocaine=== | |||
| ⚫ | Working with ] leaves, Gaedcke isolated the cocaine molecule.<ref name="West"/> Gaedcke named the alkaloid “erythroxyline,” and published a description in the journal ] in 1855.<ref>{{cite journal | ||
| | title = Ueber das Erythroxylin, dargestellt aus den Blättern des in Südamerika cultivirten Strauches Erythroxylon Coca Lam | | title = Ueber das Erythroxylin, dargestellt aus den Blättern des in Südamerika cultivirten Strauches Erythroxylon Coca Lam | ||
| | author = F. Gaedcke | | author = F. Gaedcke | ||
| Line 33: | Line 37: | ||
| | pages = 141–150 | | pages = 141–150 | ||
| | year = 1855 | | year = 1855 | ||
| | url = | | url = https://zenodo.org/record/1424529 | ||
| | doi = 10.1002/ardp.18551320208 }}</ref><ref>{{cite journal | | doi = 10.1002/ardp.18551320208 | s2cid = 86030231 | ||
| }}</ref><ref>{{cite journal | |||
| | title = Early history of cocaine isolation: Domitzer pharmacist Friedrich Gaedcke (1828–1890); contribution to Mecklenburg pharmaceutical history | | title = Early history of cocaine isolation: Domitzer pharmacist Friedrich Gaedcke (1828–1890); contribution to Mecklenburg pharmaceutical history | ||
| | author = Zaunick R. | | author = Zaunick R. | ||
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| | year = 1956 | | year = 1956 | ||
| | url = | | url = | ||
| | pmid = 13395966}}</ref> He described the alkaloid as being of small crystal molecules with needle-like points on four to six sides.<ref name="West"/> He reported the numbing effects of the molecule on himself following a small tongue test.<ref name="West"/> Gaedcke's research received little attention at the time of its publication but would come to prominence a few years later following further work by ] and scientists.<ref name="West"/> He is believed to have carried out his research in the private laboratory of ].<ref>Anesthesia History Association Newsletter, Volumes 1–13, Issue 2. 1982, page 4</ref> | |||
| | pmid = 13395966}}</ref> | |||
| ⚫ | Gaedcke worked in a pharmacy in ] and studied in Rostock between 1850 and 1851. In 1856, he took over a pharmacy in ] which he ran for |
||
| 4 years. | |||
| ==References== | ==References== | ||
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| ] | ] | ||
| ] | ] | ||
| ] | ] | ||
| ] | |||
Latest revision as of 10:59, 30 June 2024
German chemist (1828–1890)| Friedrich Gaedcke | |
|---|---|
| Born | 5 June 1828 |
| Died | 19 September 1890 (1890-09-20) (aged 62) |
| Nationality | German |
| Known for | discovering cocaine |
| Scientific career | |
| Fields | pharmaceutics |
Friedrich Georg Carl (Friedrich) Gaedcke (5 June 1828 – 19 September 1890) was a German chemist. He was the first person to isolate the cocaine alkaloid in 1855.
Life
Gaedcke worked in a pharmacy in Rostock and studied in Rostock between 1850 and 1851. In 1856, he took over a pharmacy in Dömitz which he ran for 34 years. He is described as having made contributions to the pharmaceutical history of Mecklenburg
Discovery of Cocaine
Working with coca leaves, Gaedcke isolated the cocaine molecule. Gaedcke named the alkaloid “erythroxyline,” and published a description in the journal Archiv der Pharmazie in 1855. He described the alkaloid as being of small crystal molecules with needle-like points on four to six sides. He reported the numbing effects of the molecule on himself following a small tongue test. Gaedcke's research received little attention at the time of its publication but would come to prominence a few years later following further work by Albert Niemann and scientists. He is believed to have carried out his research in the private laboratory of Franz Leopold Sonnenschein.
References
- ^ "[Early history of cocaine isolation: Domitzer pharmacist Friedrich Gaedcke (1828-1890); contribution to Mecklenburg pharmaceutical history]". PubMed. Retrieved 30 June 2024.
- Luch, Andreas (2009-04-03). Molecular, Clinical and Environmental Toxicology. Basel Boston: Springer Science & Business Media. p. 20. ISBN 978-3-7643-8336-7.
- ^ West, Krista (2008). Cocaine and Crack. Infobase Publishing. p. 47. ISBN 978-1-4381-1822-2.
- F. Gaedcke (1855). "Ueber das Erythroxylin, dargestellt aus den Blättern des in Südamerika cultivirten Strauches Erythroxylon Coca Lam". Archiv der Pharmazie. 132 (2): 141–150. doi:10.1002/ardp.18551320208. S2CID 86030231.
- Zaunick R. (1956). "Early history of cocaine isolation: Domitzer pharmacist Friedrich Gaedcke (1828–1890); contribution to Mecklenburg pharmaceutical history". Beitr Gesch Pharm Ihrer Nachbargeb. 7 (2): 5–15. PMID 13395966.
- Anesthesia History Association Newsletter, Volumes 1–13, Issue 2. 1982, page 4
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