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			{{Short description\|German microbial culture collection}}
		⚫	{{third-party\|date=October 2014}}
	{{Infobox organization		{{Infobox organization
	\| name = ~~Deutsche~~ ~~Sammlung~~ ~~von~~ ~~Mikroorganismen~~ ~~und~~ ~~Zellkulturen~~		\| name = Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures GmbH
	\| native_name =		\| native_name =
	\| native_name_lang =		\| native_name_lang =
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	\| alt =		\| alt =
	\| caption =		\| caption =
	\| logo =		\| logo = DSMZ-Logo-DE.jpg
	\| logo_size =		\| logo_size =
	\| logo_alt =		\| logo_alt =
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	\| abbreviation = DSMZ		\| abbreviation = DSMZ
	\| motto =		\| motto =
	\| predecessor =		\| predecessor = Collection of Microorganisms Göttingen (SMG)
	\| merged =		\| merged = German Collection of Microorganisms (DSM)
	\| successor =		\| successor =
	\| formation = 1969		\| formation = 1969
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	\| merger =		\| merger =
	\| type = Independent, non-profit organization		\| type = Independent, non-profit organization
	\| ~~tax_id~~ = ~~<!-- or \| vat_id = (for European organizations) -->~~		\| vat_id =
	\| registration_id = <!-- for non-profit org -->		\| registration_id = <!-- for non-profit org -->
	\| status =		\| status =
	\| purpose = National culture collection		\| purpose = National culture collection
	\| headquarters =		\| headquarters =
	\| location = ~~Germany~~		\| location = ]
	\| coords = <!-- {{coord\|LAT\|LON\|display=inline, title}} -->		\| coords = <!-- {{coord\|LAT\|LON\|display=inline, title}} -->
	\| region =		\| region =
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	\| products =		\| products =
	\| methods =		\| methods =
	\| fields =		\| fields = ], ]
	\| membership =		\| membership =
	\| membership_year =		\| membership_year =
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	\| sec_gen =		\| sec_gen =
	\| leader_title =		\| leader_title =
	\| leader_name = Jörg Overmann		\| leader_name = Jörg Overmann (scientific director), Bettina Fischer (administrative director)
	\| leader_title2 =		\| leader_title2 =
	\| leader_name2 =		\| leader_name2 =
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	\| subsidiaries =		\| subsidiaries =
	\| secessions =		\| secessions =
	\| affiliations = ~~European~~ ~~Culture Collections' Organisation~~		\| affiliations = ]
	\| budget =		\| budget =
	\| budget_year =		\| budget_year =
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	\| expenses_year =		\| expenses_year =
	\| endowment =		\| endowment =
	\| staff =		\| staff = 192 (status: December 2020)
	\| staff_year =		\| staff_year =
	\| volunteers =		\| volunteers =
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	}}		}}

			The '''Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures GmbH''' (German: ''Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH''), located in ], is a research infrastructure in the ]. Also the DSMZ is the world's most diverse collection of ] (status 2021: 75,000 bioresources).<ref name=":0">{{Cite web \|title=Mission \|url=https://www.dsmz.de/dsmz/portrait/mission \|access-date=2023-11-30 \|website=German Collection of Microorganisms and Cell Cultures GMBH}}</ref><ref name=":1">{{Cite web \|title=Catalogue \|url=https://www.dsmz.de/collection/catalogue \|access-date=2023-11-30 \|website=German Collection of Microorganisms and Cell Cultures GMBH}}</ref> These include ] (including more than 32,000 ] strains, 690 ] strains, 7,000 strains of ] and ]) as well as more than 840 human and animal ], over 1,500 ], over 940 ], and 250 ] (status 2021).<ref name=":1" /> Since 2010, the scientific director of the Leibniz Institute DSMZ has been Jörg Overmann, a microbiologist with a PhD from the University of Konstanz.<ref name=":2">{{Cite web \|title=Management \|url=https://www.dsmz.de/dsmz/portrait/management \|website=German Collection of Microorganisms and Cell Cultures GMBH}}</ref> He holds a professorship in ] at the ].<ref name=":2" /> Since August 2018, he has led the institute with leadership with Bettina Fischer as administrative director.<ref name=":2" />
⚫	{{third-party\|date=October 2014}}

			== History ==
	The '''Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures GmbH''' ('''Deutsche Sammlung von Mikroorganismen und Zellkulturen''' GmbH) (abbreviation is '''DSM''' and '''DSMZ'''<ref>.</ref>) was founded 1969 as the national culture collection in Germany. This independent non-profit organization is dedicated to the acquisition, characterization, identification, preservation, distribution of ], ], ], ], ], ], ] and ]. The organization is member of the German ] and of worldwide organizations like the ] (ECCO), the ] (WFCC), and the ] (GBIF).
			{\| class="wikitable"
			\|+
			!Year
			!Event
			\|-
			\|1969
			\|Establishment Collection of Microorganisms Göttingen (SMG) in the Department of Nutritional Physiology of Microorganisms with Microbial Bank (Administrative Head D. Claus) at the Göttingen Institute of Microbiology of the Society for Radiation Research
			\|-
			\|1973
			\|Official name: German Collection of Microorganisms (DSM)
			\|-
			\|1974
			\|Recognition as official depository by the German Patent Office
			\|-
			\|1976
			\|DSM is spun off and run independently at the Institute of Microbiology
			\|-
			\|1979
			\|Transfer to the Society for Biotechnological Research Braunschweig (Director D. Claus)
			\|-
			\|1981
			\|Recognition as international depository for patent purposes according to the Budapest Treaty
			\|-
			\|1987
			\|Establishment of plant cell lines and human and animal cell cultures as new collection areas
			\|-
			\|1988
			\|Renaming to German Collection of Microorganisms and Cell Cultures. DSMZ becomes a GmbH (limited liability company) with the state of Lower Saxony as sole shareholder
			\|-
			\|1990
			\|Plant virus collection added
			\|-
			\|1996
			\|Promotion of the DSMZ as a Blue List institution and subsequently member of the ]
			\|-
			\|2010
			\|Establishment of the collection-independent research area Department of ''Microbial Ecology and Diversity Research''
			\|-
			\|2011
			\|Renaming to Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures GmbH
			\|-
			\|2014
			\|Establishment of the research department ''Microbial Genomics'' as part of DSMZ's participation in the German Center for Infection Research
			\|-
			\|2016
			\|Establishment of the new collection department ''Bioresources for Bioeconomy and Health Research''
			\|-
			\|2018
			\|DSMZ becomes the first registered collection for the implementation of the Nagoya Protocol in the EU
			\|-
			\|2020
			\|Move-in of the ''Bioresources for Bioeconomy and Health Research'' Department into the new Center for Drug and Functional Genomics Research. Successful evaluation by the Senate of the ].
			\|}

			==Structure==
	The DSMZ has close working links with several other international culture collections, including the ] (ICMP) in New Zealand, the CFBP in France, the ] (BCCM/LMG) in Belgium, the ] (NCPPB) in the UK, and others.
			Nearly 200 scientists and technical staff currently work at the DSMZ.<ref>{{Cite web \|date=2019-10-21 \|title=Bakterien für ein besseres und gesünderes Leben \|trans-title=Bacteria for a better and healthier life \|url=https://www.dsmz.de/press/press-releases/singleview/bakterien-fuer-ein-besseres-und-gesuenderes-leben \|website=German Collection of Microorganisms and Cell Cultures GMBH \|language=de}}</ref> It is a company/non-profit organization recognized as a public benefit.<ref name=":0" /> In 2018, the Leibniz Institute DSMZ was recognized as the world's first registered collection under ] 511/2014, providing all users with the necessary legal certainty in the handling of their bioresources in accordance with the ].<ref>{{Cite web \|title=Collection \|url=https://www.dsmz.de/collection \|access-date=2023-11-30 \|website=German Collection of Microorganisms and Cell Cultures GMBH}}</ref><ref>{{Cite web \|title=Nagoya Protocol \|url=https://www.dsmz.de/collection/nagoya-protocol \|access-date=2023-11-30 \|website=German Collection of Microorganisms and Cell Cultures GMBH}}</ref>
			The DSMZ is a partner in international organizations such as the ] (ECCO), the ] (WFCC) and the ] (GBIF).<ref>{{Cite web \|title=German Collection of Microorganisms and Cell Cultures GMBH: Network \|url=https://www.dsmz.de/dsmz/network \|access-date=2023-12-26 \|website=German Collection of Microorganisms and Cell Cultures GMBH}}</ref>

			==Functions==
	Jörg Overmann has acted as scientific director since 2010.
			DSMZ is a global service provider with more than 10,000 customers in over 80 countries and provides microorganisms and cell cultures for university, non-university and industrial research in the ]. It also serves as a patent and security depository for biological material (a total of over 11,700 bioresources) in accordance with the guidelines of the ].<ref>{{Cite web \|title=Guide to the Deposit of Microorganisms under the Budapest Treaty \|url=https://www.wipo.int/treaties/en/registration/budapest/guide/index.html \|archive-url=https://web.archive.org/web/20201118130634/https://www.wipo.int/treaties/en/registration/budapest/guide/index.html \|archive-date=2020-11-18 \|website=World Intellectual Property Organization}}</ref> It is the only patent depository for bioresources in Germany.<ref>{{Cite web \|title=Patent Deposit \|url=https://www.dsmz.de/collection/deposit/patent-deposit \|access-date=2023-11-30 \|website=German Collection of Microorganisms and Cell Cultures GMBH}}</ref> The DSMZ only holds bioresources in ] 1 and 2.

			In 2012, the freely accessible ] BacDive (The Bacterial Diversity Metadatabase)<ref>{{Cite web \|title=BacDive \|url=https://www.dsmz.de/services/online-tools/bacdive \|website=German Collection of Microorganisms and Cell Cultures GMBH}}</ref> was established, which is maintained and curated by the DSMZ. The database contains information on a wide variety of strains of ]; in 2016, information on 53,978 strains could be found there,<ref>{{Cite journal\|url=https://academic.oup.com/nar/article/44/D1/D581/2503137?login=false\| journal=Nucleic Acids Research \| date=4 January 2016 \| volume=44 \| issue=D1 \| pages=D581–D585 \| doi=10.1093/nar/gkv983 \| last1=Söhngen \| first1=Carola \| last2=Podstawka \| first2=Adam \| last3=Bunk \| first3=Boyke \| last4=Gleim \| first4=Dorothea \| last5=Vetcininova \| first5=Anna \| last6=Reimer \| first6=Lorenz Christian \| last7=Ebeling \| first7=Christian \| last8=Pendarovski \| first8=Cezar \| last9=Overmann \| first9=Jörg \| title=Bac ''Dive'' – the Bacterial Diversity Metadatabase in 2016 \| pmid=26424852 \| pmc=4702946 }}</ref> and by 2021, the number had increased to more than 82,000.<ref>{{Cite web \|title=BacDive {{!}} The Bacterial Diversity Metadatabase \|url=https://bacdive.dsmz.de/ \|access-date=2023-12-01 \|website=bacdive.dsmz.de}}</ref>
	==Collection and services==

			==Departments==
	The DSMZ has, at present,{{when\|date=May 2018}} about 30,000 cultures, including 19,000 different cultures of microorganisms, 41 plant cell cultures, 1400 plant viruses, 800 human and animal cell lines, and 6700 patent deposits and safe deposits.
			In addition to the research departments ''Microbial Ecology and Diversity Research'' <ref>{{Cite web \|title=Microbial Ecology and Diversity Research \|url=https://www.dsmz.de/research/microbial-ecology-and-diversity-research \|website=German Collection of Microorganisms and Cell Cultures GMBH}}</ref> and ''Microbial Genome Research'',<ref>{{Cite web \|title=Microbial Genome Research \|url=https://www.dsmz.de/research/microbial-genome-research \|website=German Collection of Microorganisms and Cell Cultures GMBH}}</ref> the eight departments of the DSMZ include the collection departments ''Microorganisms'',<ref>{{Cite web \|title=Microorganisms \|url=https://www.dsmz.de/research/microorganisms \|website=German Collection of Microorganisms and Cell Cultures GMBH}}</ref> ''Bioresources for Bioeconomy and Health Research'',<ref>{{Cite web \|title=Bioresources for Bioeconomy and Health Research \|url=https://www.dsmz.de/research/bioresources-for-bioeconomy-and-health-research \|website=German Collection of Microorganisms and Cell Cultures GMBH}}</ref> ''Human and Animal Cell Lines''<ref>{{Cite web \|title=Human and Animal Cell Lines \|url=https://www.dsmz.de/research/human-and-animal-cell-lines \|website=German Collection of Microorganisms and Cell Cultures GMBH}}</ref> and ''Plant Viruses'' <ref>{{Cite web \|title=Plant Viruses \|url=https://www.dsmz.de/research/plant-viruses \|website=German Collection of Microorganisms and Cell Cultures GMBH}}</ref> as well as the departments ''Analytics'' <ref>{{Cite web \|title=Analytics \|url=https://www.dsmz.de/research/analytics \|website=German Collection of Microorganisms and Cell Cultures GMBH}}</ref> and ''Bioinformatics and Databases''.<ref>{{Cite web \|title=Bioinformatics \|url=https://www.dsmz.de/research/bioinformatics \|website=German Collection of Microorganisms and Cell Cultures GMBH}}</ref> The establishment of independent junior research groups (as of 2021: ''VirusInteract'' (interactions of plant viruses with their hosts) and ''Microbial Biotechnology'') provides qualification opportunities for young scientists conducting research on selected, current topics.
	Only biological material of ] 1 and 2 is housed.
	The scientific services are offered to support fundamental research and processes of industrial production or ecological development, but also for the elucidation and solution of biological material.
	The DSMZ is recognized as an ] (IDA) for the deposit of biological material under the ].
	Information on cultures and services, catalogues and lists are available online at the DSMZ website.<ref>, www.dsmz.de</ref>

	The DSMZ offers ] services such as databases on bacterial nomenclature and diversity, and tools to calculate ] values from genome sequences for microbial classification.<ref>, ggdc.dsmz.de</ref>

	It also manages the online metadatabase ], which provides strain-linked information about bacterial and archeal biodiversity.<ref>, bacdive.dsmz.de</ref>

	==Research==

	The research activities at DSMZ are focussed on collection-related fields, including microbial ], ], ], molecular ] studies, development of preservation methods for biological material, characterization and identification of cell lines and microorganisms as well as detection and elimination of mycoplasms and viruses from human and animal cell lines.
	The DSMZ is involved in several large-scale ] projects in collaboration with the ].

	== References ==		== References ==
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	{{Authority control}}		{{Authority control}}
	{{Leibniz Association}}		{{Leibniz Association}}

	]		]
	]		]
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	]		]
	]		]
			]

Latest revision as of 02:25, 27 December 2023

German microbial culture collection

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Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures GmbH

Abbreviation	DSMZ
Predecessor	Collection of Microorganisms Göttingen (SMG)
Merged into	German Collection of Microorganisms (DSM)
Formation	1969
Type	Independent, non-profit organization
Purpose	National culture collection
Location	Braunschweig
Fields	Microbiology, Cell Biology
Leader	Jörg Overmann (scientific director), Bettina Fischer (administrative director)
Affiliations	Leibniz Association
Staff	192 (status: December 2020)
Website	www.dsmz.de

The Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures GmbH (German: Leibniz-Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH), located in Braunschweig, is a research infrastructure in the Leibniz Association. Also the DSMZ is the world's most diverse collection of bioresources (status 2021: 75,000 bioresources). These include microorganisms (including more than 32,000 bacterial strains, 690 archaeal strains, 7,000 strains of yeasts and fungi) as well as more than 840 human and animal cell cultures, over 1,500 plant viruses, over 940 bacteriophages, and 250 plasmids (status 2021). Since 2010, the scientific director of the Leibniz Institute DSMZ has been Jörg Overmann, a microbiologist with a PhD from the University of Konstanz. He holds a professorship in microbiology at the Technical University of Braunschweig. Since August 2018, he has led the institute with leadership with Bettina Fischer as administrative director.

History


Year	Event
1969	Establishment Collection of Microorganisms Göttingen (SMG) in the Department of Nutritional Physiology of Microorganisms with Microbial Bank (Administrative Head D. Claus) at the Göttingen Institute of Microbiology of the Society for Radiation Research
1973	Official name: German Collection of Microorganisms (DSM)
1974	Recognition as official depository by the German Patent Office
1976	DSM is spun off and run independently at the Institute of Microbiology
1979	Transfer to the Society for Biotechnological Research Braunschweig (Director D. Claus)
1981	Recognition as international depository for patent purposes according to the Budapest Treaty
1987	Establishment of plant cell lines and human and animal cell cultures as new collection areas
1988	Renaming to German Collection of Microorganisms and Cell Cultures. DSMZ becomes a GmbH (limited liability company) with the state of Lower Saxony as sole shareholder
1990	Plant virus collection added
1996	Promotion of the DSMZ as a Blue List institution and subsequently member of the Leibniz Association
2010	Establishment of the collection-independent research area Department of Microbial Ecology and Diversity Research
2011	Renaming to Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures GmbH
2014	Establishment of the research department Microbial Genomics as part of DSMZ's participation in the German Center for Infection Research
2016	Establishment of the new collection department Bioresources for Bioeconomy and Health Research
2018	DSMZ becomes the first registered collection for the implementation of the Nagoya Protocol in the EU
2020	Move-in of the Bioresources for Bioeconomy and Health Research Department into the new Center for Drug and Functional Genomics Research. Successful evaluation by the Senate of the Leibniz Association.

Structure

Nearly 200 scientists and technical staff currently work at the DSMZ. It is a company/non-profit organization recognized as a public benefit. In 2018, the Leibniz Institute DSMZ was recognized as the world's first registered collection under Directive (European Union) 511/2014, providing all users with the necessary legal certainty in the handling of their bioresources in accordance with the Nagoya Protocol. The DSMZ is a partner in international organizations such as the European Culture Collections' Organisation (ECCO), the World Federation for Culture Collections (WFCC) and the Global Biodiversity Information Facility (GBIF).

Functions

DSMZ is a global service provider with more than 10,000 customers in over 80 countries and provides microorganisms and cell cultures for university, non-university and industrial research in the life sciences. It also serves as a patent and security depository for biological material (a total of over 11,700 bioresources) in accordance with the guidelines of the Budapest Treaty. It is the only patent depository for bioresources in Germany. The DSMZ only holds bioresources in biosafety level 1 and 2.

In 2012, the freely accessible database BacDive (The Bacterial Diversity Metadatabase) was established, which is maintained and curated by the DSMZ. The database contains information on a wide variety of strains of prokaryotes; in 2016, information on 53,978 strains could be found there, and by 2021, the number had increased to more than 82,000.

Departments

In addition to the research departments Microbial Ecology and Diversity Research and Microbial Genome Research, the eight departments of the DSMZ include the collection departments Microorganisms, Bioresources for Bioeconomy and Health Research, Human and Animal Cell Lines and Plant Viruses as well as the departments Analytics and Bioinformatics and Databases. The establishment of independent junior research groups (as of 2021: VirusInteract (interactions of plant viruses with their hosts) and Microbial Biotechnology) provides qualification opportunities for young scientists conducting research on selected, current topics.

References

^ "Mission". German Collection of Microorganisms and Cell Cultures GMBH. Retrieved 2023-11-30.
^ "Catalogue". German Collection of Microorganisms and Cell Cultures GMBH. Retrieved 2023-11-30.
^ "Management". German Collection of Microorganisms and Cell Cultures GMBH.
"Bakterien für ein besseres und gesünderes Leben" [Bacteria for a better and healthier life]. German Collection of Microorganisms and Cell Cultures GMBH (in German). 2019-10-21.
"Collection". German Collection of Microorganisms and Cell Cultures GMBH. Retrieved 2023-11-30.
"Nagoya Protocol". German Collection of Microorganisms and Cell Cultures GMBH. Retrieved 2023-11-30.
"German Collection of Microorganisms and Cell Cultures GMBH: Network". German Collection of Microorganisms and Cell Cultures GMBH. Retrieved 2023-12-26.
"Guide to the Deposit of Microorganisms under the Budapest Treaty". World Intellectual Property Organization. Archived from the original on 2020-11-18.
"Patent Deposit". German Collection of Microorganisms and Cell Cultures GMBH. Retrieved 2023-11-30.
"BacDive". German Collection of Microorganisms and Cell Cultures GMBH.
Söhngen, Carola; Podstawka, Adam; Bunk, Boyke; Gleim, Dorothea; Vetcininova, Anna; Reimer, Lorenz Christian; Ebeling, Christian; Pendarovski, Cezar; Overmann, Jörg (4 January 2016). "Bac Dive – the Bacterial Diversity Metadatabase in 2016". Nucleic Acids Research. 44 (D1): D581 – D585. doi:10.1093/nar/gkv983. PMC 4702946. PMID 26424852.
"BacDive | The Bacterial Diversity Metadatabase". bacdive.dsmz.de. Retrieved 2023-12-01.
"Microbial Ecology and Diversity Research". German Collection of Microorganisms and Cell Cultures GMBH.
"Microbial Genome Research". German Collection of Microorganisms and Cell Cultures GMBH.
"Microorganisms". German Collection of Microorganisms and Cell Cultures GMBH.
"Bioresources for Bioeconomy and Health Research". German Collection of Microorganisms and Cell Cultures GMBH.
"Human and Animal Cell Lines". German Collection of Microorganisms and Cell Cultures GMBH.
"Plant Viruses". German Collection of Microorganisms and Cell Cultures GMBH.
"Analytics". German Collection of Microorganisms and Cell Cultures GMBH.
"Bioinformatics". German Collection of Microorganisms and Cell Cultures GMBH.

v t e Leibniz Association
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