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Elliot takes issue with the endearments Dr. Kelso uses on her, but naively follows Dr. Cox's advice and confronts him over it. J.D. begins to miss Turk's company with how busy both of them are; however J.D. suspects a post-op reaction with a patient just out of surgery might have something to do with him. Elliot and J.D. seem to be getting close, but an interruption might make the difference between being friends and something more than that. J.D. thinks he now has 48 hours to kiss Elliot before entering the "Friends Zone". In the end he doesn't get the kiss, deciding to be a friend to Elliot at the time. Meanwhile, J.D.'s fear of Turk no longer looking out for him is eventually proved unfounded. The patient that J.D. thought was deteriorating because of Turk's carelessness in post-op was actually diabetic, and J.D.'s treatment of insulin was actually what was damaging him. In the end, Turk was looking out for J.D. - it was Carla who realized that the patient was a diabetic and had subsequently stopped the treatment of insulin.
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The Erasure song "A Little Respect", that Dr. Wen turns out to be a great fan of, can be heard a number of times in this episode.
According to J.D., this episode is solely responsible for him and Elliot never dating. He believes that if he had made it to Elliot at the end of the episode a couple of minutes earlier, they would have dated.
The door to the "Friend Zone" in J.D.'s fantasy sequence is labelled 'S2-43', which means that in season two, J.D. and Elliot would still be friends.
When J.D. and Dr. Cox walk into the lobby, and J.D. looks out into the hall and sees Turk say, "That song is like a virus" his shirt is purple. When he looks away and goes towards Dr. Cox, it's dark blue. This may be due to the lighting.
