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Antiserotoninergic agent, antidepressant, analgesic.<ref> Huegi, Bruno S.; Ebnoether, Anton M.; Rissi, Erwin; Gadient, Fulvio; Hauser, Daniel; Roemer, Dietmar; Buescher, Heinz H.; Petcher, Trevor J. (1983). "Synthesis and pharmacological studies of 4,4-disubstituted piperidines: a new class of compounds with potent analgesic properties". Journal of Medicinal Chemistry 26 (1): 42–50. doi:10.1021/jm00355a010.</ref> Antiserotoninergic agent, antidepressant, analgesic.<ref> Huegi, Bruno S.; Ebnoether, Anton M.; Rissi, Erwin; Gadient, Fulvio; Hauser, Daniel; Roemer, Dietmar; Buescher, Heinz H.; Petcher, Trevor J. (1983). "Synthesis and pharmacological studies of 4,4-disubstituted piperidines: a new class of compounds with potent analgesic properties". Journal of Medicinal Chemistry 26 (1): 42–50. doi:10.1021/jm00355a010.</ref>

Patents:<ref>Erwin Rissi & Anton Ebnother, US4178377 (1979 to Sandoz KK).</ref><ref>Erwin Rissi & Anton Ebnother, US4248877 (1981 to Sandoz AG).</ref>
==See also== ==See also==
*] *]

Revision as of 17:51, 17 December 2024

Pipradimadol
Clinical data
Other namesFU 29-245
Identifiers
IUPAC name
  • 2--4-hydroxypiperidin-4-yl]-N-cyclohexyl-N,2-dimethylpropanamide
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC24H37ClN2O2
Molar mass421.02 g·mol
3D model (JSmol)
SMILES
  • CC(C)(C(=O)N(C)C1CCCCC1)C2(CCN(CC2)CCC3=CC=CC=C3Cl)O
InChI
  • InChI=1S/C24H37ClN2O2/c1-23(2,22(28)26(3)20-10-5-4-6-11-20)24(29)14-17-27(18-15-24)16-13-19-9-7-8-12-21(19)25/h7-9,12,20,29H,4-6,10-11,13-18H2,1-3H3
  • Key:CNIMNQJXZKALLC-UHFFFAOYSA-N

Antiserotoninergic agent, antidepressant, analgesic.

Patents:

See also

References

  1. Huegi, Bruno S.; Ebnoether, Anton M.; Rissi, Erwin; Gadient, Fulvio; Hauser, Daniel; Roemer, Dietmar; Buescher, Heinz H.; Petcher, Trevor J. (1983). "Synthesis and pharmacological studies of 4,4-disubstituted piperidines: a new class of compounds with potent analgesic properties". Journal of Medicinal Chemistry 26 (1): 42–50. doi:10.1021/jm00355a010.
  2. Erwin Rissi & Anton Ebnother, US4178377 (1979 to Sandoz KK).
  3. Erwin Rissi & Anton Ebnother, US4248877 (1981 to Sandoz AG).
Antidepressants (N06A)
Specific reuptake inhibitors and/or receptor modulators
SSRIsTooltip Selective serotonin reuptake inhibitors
SNRIsTooltip Serotonin–norepinephrine reuptake inhibitors
NRIsTooltip Norepinephrine reuptake inhibitors
NDRIsTooltip Norepinephrine–dopamine reuptake inhibitors
NaSSAsTooltip Noradrenergic and specific serotonergic antidepressants
SARIsTooltip Serotonin antagonist and reuptake inhibitors
SMSTooltip Serotonin modulator and stimulators
Others
Tricyclic and tetracyclic antidepressants
TCAsTooltip Tricyclic antidepressants
TeCAsTooltip Tetracyclic antidepressants
Others
Monoamine oxidase inhibitors
Non-selective
MAOATooltip Monoamine oxidase A-selective
MAOBTooltip Monoamine oxidase B-selective
Adjunctive therapies
Miscellaneous
Opioid receptor modulators
μ-opioid
(MOR)
Agonists
(abridged;
full list)
Antagonists
δ-opioid
(DOR)
Agonists
Antagonists
κ-opioid
(KOR)
Agonists
Antagonists
Nociceptin
(NOP)
Agonists
Antagonists
Others
  • Others: Kyotorphin (met-enkephalin releaser/degradation stabilizer)

Categories: