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'''Noradrenergic and specific serotonergic antidepressants''' (abbreviated: '''NaSSAs''') are a relatively new class of ]s.<ref>{{cite journal |author=Kent J |title=SNaRIs, NaSSAs, and NaRIs: new agents for the treatment of depression |journal=Lancet |volume=355 |issue=9207 |pages=911-8 |year=2000 |pmid=10752718}}</ref> They are thought to work by blocking presynaptic alpha-2 ] that normally inhibit the release of the ]s ] (]) and ]. This results in increases in both noradrenergic and specific serotonergic transmission.


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Examples of NaSSAs include:
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* ] (Remeron®, Zispin®, Avanza®, Norset®, Remergil®, Axit®)


stephen sucks
NaSSAs are said to have fewer side effects than ]s and ]s (SSRIs) while being equally effective. In particular, it is said that the sexual dysfunction that is a relatively common side effect of SSRIs occurs significantly less often during treatment with Mirtazapine.<ref>{{cite journal |author=Fawcett J, Barkin R |title=Review of the results from clinical studies on the efficacy, safety and tolerability of mirtazapine for the treatment of patients with major depression |journal=J Affect Disord |volume=51 |issue=3 |pages=267-85 |year=1998 |pmid=10333982}} </ref>

==See also==

* ]

==References==
<references/>

]

]


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{{Antidepressants}}

Revision as of 21:11, 4 October 2007

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stephen sucks