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| Deep TMS uses the basic principles of ] (TMS) but expands them from the use of a single focal stimulation source to a summation of several simultaneous operating elements. The brain regions affected directly by this technique are determined by the shape of the TMS coil. Standard TMS coils induce direct stimulation of superficial brain areas, while Deep TMS coils (H-coils) induce summation of fields, allowing deeper penetration of the brain. To affect different areas of the brain (depending on the targeted disorder), specific versions of H-coils are installed within a helmet placed on the subject's head.{{cn|date=November 2013}} | Deep TMS uses the basic principles of ] (TMS) but expands them from the use of a single focal stimulation source to a summation of several simultaneous operating elements. The brain regions affected directly by this technique are determined by the shape of the TMS coil. Standard TMS coils induce direct stimulation of superficial brain areas, while Deep TMS coils (H-coils) induce summation of fields, allowing deeper penetration of the brain. To affect different areas of the brain (depending on the targeted disorder), specific versions of H-coils are installed within a helmet placed on the subject's head.{{cn|date=November 2013}} | ||
| Deep TMS coils have been studied in healthy humans and people with ], ], ], ]s, and ].<ref>{{cite pmid|15792886}}</ref><ref>{{cite pmid|22559998}}<ref> | Deep TMS coils have been studied in healthy humans and people with ], ], ], ]s, and ].<ref>{{cite pmid|15792886}}</ref><ref>{{cite pmid|22559998}}</ref> | ||
| ==History== | ==History== | ||
Revision as of 00:46, 21 November 2013
Medical intervention| Deep transcranial magnetic stimulation | |
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| File:H-coil helmet.jpgH-coil helmet for deep transcranial magnetic stimulation (schematic diagram) | |
| [edit on Wikidata] |
Deep transcranial magnetic stimulation (Deep TMS) is a non-invasive technique for excitation of large populations of neurons in the brain.
Use
Deep TMS uses the basic principles of transcranial magnetic stimulation (TMS) but expands them from the use of a single focal stimulation source to a summation of several simultaneous operating elements. The brain regions affected directly by this technique are determined by the shape of the TMS coil. Standard TMS coils induce direct stimulation of superficial brain areas, while Deep TMS coils (H-coils) induce summation of fields, allowing deeper penetration of the brain. To affect different areas of the brain (depending on the targeted disorder), specific versions of H-coils are installed within a helmet placed on the subject's head.
Deep TMS coils have been studied in healthy humans and people with major depressive disorder, autism, bipolar disorder, auditory hallucinations, and schizophrenia.
History
The technology was developed by Abraham Zangen and Yiftach Roth starting in 2001 and a patent was filed by the United States National Institutes of Health. In January 2013, the United States Food and Drug Administration permitted a manufacturer to market a Deep TMS device that was indicated for the treatment of depressive episodes in adult patients suffering from major depressive disorder who failed to achieve satisfactory improvement from previous anti-depressant medication treatment in the current episode.
References
- Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 15792886, please use {{cite journal}} with
|pmid=15792886instead. - Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 22559998, please use {{cite journal}} with
|pmid=22559998instead. - Krauthamer, Victor (2013-01-07). "Letter to Brainsway, Ltd" (PDF). 510(k)Summary for K12288: Brainsway Deep TMS System. Silver Spring, MD: Office of Device Evaluation, Center for Devices and Radiological Health, Food and Drug Administration. Retrieved 2013-11-20.