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ERV-Fc is an endogenous retrovirus (ERV). It was active and infectious among many species of mammals, jumping species more than 20 times, between about 33 million and about 15 million years ago, in the Oligocene and early Miocene, in the Americas and Europe and Asia and Africa and India, but not Australia or Antarctica. After about 15 million years ago, it became extinct as an active infectious virus, but inactive damaged copies and parts of copies survive as inclusions in the hereditary DNA of many species of mammals including Man.<ref>Tracking interspecies transmission and long-term evolution of an ancient retrovirus using the genomes of modern mammals, by William E Diehl, Nirali Patel, Kate Halm, Welkin E Johnson. Boston College, United States. Areas: evolutionary biology, microbiology, infectious disease. Research Article Mar 8, 2016
External links
- Tracking interspecies transmission and long-term evolution of an ancient retrovirus using the genomes of modern mammals
- The Pandemic That Lasted 15 Million Years; Youtube video, 10.06 minutes long, uploaded 28 January 2021, by PBS Eons
- Scientists uncover history of ancient viruses as far back as 30 million years ago
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