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Revision as of 05:43, 15 June 2020 editBoghog (talk | contribs)Autopatrolled, Extended confirmed users, IP block exemptions, New page reviewers, Pending changes reviewers, Rollbackers, Template editors137,747 edits consistent citation formatting← Previous edit Latest revision as of 23:49, 5 April 2023 edit undoEntranced98 (talk | contribs)Extended confirmed users, Pending changes reviewers, Rollbackers172,583 edits Adding local short description: "Monoclonal antibody", overriding Wikidata description "chemical compound"Tag: Shortdesc helper 
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{{Short description|Monoclonal antibody}}
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Latest revision as of 23:49, 5 April 2023

Monoclonal antibody Pharmaceutical compound
Urtoxazumab
Monoclonal antibody
TypeWhole antibody
SourceHumanized (from mouse)
TargetE. coli Shiga-like toxin II B subunit
Clinical data
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
Chemical and physical data
FormulaC6414H9934N1718O2010S40
Molar mass144556.44 g·mol
  (what is this?)  (verify)

Urtoxazumab is a humanized monoclonal antibody against diarrhoea caused by Escherichia coli, serotype O121. The drug is designed to bind to a toxin of this bacterium, so that it can be more easily broken down and eliminated from the body.

References

  1. "International Nonproprietary Names for Pharmaceutical Substances (INN)" (PDF). World Health Organization.
  2. López EL, Contrini MM, Glatstein E, González Ayala S, Santoro R, Allende D, et al. (January 2010). "Safety and pharmacokinetics of urtoxazumab, a humanized monoclonal antibody, against Shiga-like toxin 2 in healthy adults and in pediatric patients infected with Shiga-like toxin-producing Escherichia coli". Antimicrobial Agents and Chemotherapy. 54 (1): 239–43. doi:10.1128/AAC.00343-09. PMC 2798559. PMID 19822704.
Monoclonal antibodies for infectious disease and toxins
Fungal
Human
Viral
Human
Chimeric
Humanized
Bacterial
Human
Mouse
Chimeric
Humanized
Toxin
Human
Chimeric
Humanized
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