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| Although they remain effective, they have been increasingly replaced by | Although they remain effective, they have been increasingly replaced by | ||
| ]s because the difference between | ]s because the difference between | ||
| a therapeutic and a toxic dose of a tricyclic antidepressant is small. Like ]s, this posed a | a therapeutic and a toxic dose of a tricyclic antidepressant is small. Like ]s, this posed a | ||
Revision as of 04:58, 17 January 2002
Tricyclic antidepressants are a class of antidepressant drugs
first used in the 1960s.
Although they remain effective, they have been increasingly replaced by
SSRIs because the difference between
a therapeutic and a toxic dose of a tricyclic antidepressant is small. Like monoamine oxidase inhibitors, this posed a
difficulty for the physician in that they were prescribing a
medication for a depressed person that could be used to
commit suicide.