| Revision as of 23:15, 31 May 2009 editAgre22 (talk | contribs)1,619 edits →Unsourced additions← Previous edit | Revision as of 23:20, 31 May 2009 edit undoAgre22 (talk | contribs)1,619 edits →HeritabilityNext edit → | ||
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| :::Apparently my quick Google Scholar search was insufficient. Well, we should at least include some of these numbers in the article. It's vague as it is and can be more informative. ] (]) 15:15, 26 April 2009 (UTC) | :::Apparently my quick Google Scholar search was insufficient. Well, we should at least include some of these numbers in the article. It's vague as it is and can be more informative. ] (]) 15:15, 26 April 2009 (UTC) | ||
| ::::It is a fascinating subject - finding the 'best' sources (haha) can be a little tricky sometimes...our problem is the article is huge already. Might be good to exand on ]. ] (] '''·''' ]) 20:05, 26 April 2009 (UTC) | ::::It is a fascinating subject - finding the 'best' sources (haha) can be a little tricky sometimes...our problem is the article is huge already. Might be good to exand on ]. ] (] '''·''' ]) 20:05, 26 April 2009 (UTC) | ||
| I know someone with this disease, for more than 20 years.His mother, now more than 80 ears old, never had any mental problem.His father died many years ago and never had any emntal problem;he died of ] and old.Any of his six sisters or brothers has any mental problem.He is the only case of schizophrenia is his big family.Anyone reallly knows what causes schizophrenia.The cause of this disease remains a mistery.] (]) 23:20, 31 May 2009 (UTC)agre22 | |||
| == Potassium ion channels and isoform 3.1 of KCNH2 == | == Potassium ion channels and isoform 3.1 of KCNH2 == | ||
Revision as of 23:20, 31 May 2009
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Heritability
The article states that "Estimates of the heritability of schizophrenia tend to vary owing to the difficulty of separating the effects of genetics and the environment although twin studies have suggested a high level of heritability."
This language makes it sound as if heritability measures of schizophrenia are inconclusive, which does not appear to be the case. I just did a quick Google Scholar search and the estimates were all in the 80-90% range. This is an extremely high level of heritability and would warrant a much stronger conclusion than is given in the article.
I can address this myself after the semester is over, but I thought I'd throw this out there in case somebody wanted to tackle it in the next few weeks.
Josh (talk) 07:24, 25 April 2009 (UTC)
- Studies of incidence of monozygotic twins have 40-50% as the rate of the second twin getting it if the first has. Casliber (talk · contribs) 07:45, 25 April 2009 (UTC)
- One large latest study estimates genetics share at only 64% for SZ and 59% for bipolar; see PMID 19150704 and "Large Family Study Links Genetics of Schizophrenia, Bipolar Disorder" at Schizophrenia Research Forum. --CopperKettle 08:38, 25 April 2009 (UTC)
- Apparently my quick Google Scholar search was insufficient. Well, we should at least include some of these numbers in the article. It's vague as it is and can be more informative. Josh (talk) 15:15, 26 April 2009 (UTC)
- It is a fascinating subject - finding the 'best' sources (haha) can be a little tricky sometimes...our problem is the article is huge already. Might be good to exand on causes of schizophrenia. Casliber (talk · contribs) 20:05, 26 April 2009 (UTC)
- Apparently my quick Google Scholar search was insufficient. Well, we should at least include some of these numbers in the article. It's vague as it is and can be more informative. Josh (talk) 15:15, 26 April 2009 (UTC)
- One large latest study estimates genetics share at only 64% for SZ and 59% for bipolar; see PMID 19150704 and "Large Family Study Links Genetics of Schizophrenia, Bipolar Disorder" at Schizophrenia Research Forum. --CopperKettle 08:38, 25 April 2009 (UTC)
I know someone with this disease, for more than 20 years.His mother, now more than 80 ears old, never had any mental problem.His father died many years ago and never had any emntal problem;he died of prostate cancer and old.Any of his six sisters or brothers has any mental problem.He is the only case of schizophrenia is his big family.Anyone reallly knows what causes schizophrenia.The cause of this disease remains a mistery.Agre22 (talk) 23:20, 31 May 2009 (UTC)agre22
Potassium ion channels and isoform 3.1 of KCNH2
A new paper may be of interest:
Huffaker SJ, Chen J, Nicodemus KK, Sambataro F, Yang F, Mattay V, Lipska BK, Hyde TM, Song J, Rujescu D, Giegling I, Mayilyan K, Proust MJ, Soghoyan A, Caforio G, Callicott JH, Bertolino A, Meyer-Lindenberg A, Chang J, Ji Y, Egan MF, Goldberg TE, Kleinman JE, Lu B, Weinberger DR (3 May 2009). "A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia". Nature Medicine. doi:10.1038/nm.1962. {{cite journal}}: Unknown parameter |laysummary= ignored (help)CS1 maint: multiple names: authors list (link)
- Could be handy in the Causes of schizophrenia article --CopperKettle 15:51, 6 May 2009 (UTC)
nature of hallucinations
I'd like to discuss the most recent change to the lead made by Editor182 (talk · contribs). To my understanding, somatosensory disturbances are more common than visual, and perhaps olfactory too; but I'm not enough of an expert to be sure of this. Any input? Looie496 (talk) 15:13, 7 May 2009 (UTC)
- Somatosensory disturbances do occur but are not often prominent and overlap with delusions. They are much more a feature of stimulant intoxication ("formication" etc.). I wouldn't have it in the lead. Casliber (talk · contribs) 20:36, 9 May 2009 (UTC)
recognizing psychosis
Popular Hollywood films such as The Soloist and A Beautiful Mind provide true stories from the lives of patients and their families. Often relatives are not aware of key signs, nor, that early intervention can be helpful. Local mental health groups support families to seek medical advice and steps to a clear diagnosis.
Scientists collaborate in Schizophrenia Research Forum, to bring together experts from neurology, brain imaging, pharmacology to address this puzzling disease. www.schizophreniaforum.org 99.234.95.84 (talk) 15:08, 9 May 2009 (UTC)
- I agree with the mentioning of The Soloist and Schizophrenia Research Forum (a helluva website). --CopperKettle 15:35, 9 May 2009 (UTC)
Further Reading
I question the inclusion in the Further Reading section of Thomas Szasz' "Schizophrenia: the sacred symbol of psychiatry." (1976). New York: Basic Books. ISBN 0-465-07222-4.
In his excellent resource for family members "Surviving Schizophrenia: A Family Manual" (which should be on the Further Readings list), Dr. E. Fuller Torrey cites Mr. Szasz' book as one of the "ten worst readings" (Appendix A, p. 380). Dr. Torrey opines: "schizophrenia is not included among Dr. Szasz' major contributions to psychiatric theory and practice... "Page for page this book probably contains more specious reasoning than any other book on the subject... "Schizophrenia is one of the 'fake diseases', says Szasz, another of the myths of mental illness. The only myth is that Dr. Szasz knows anything whatsoever about schizophrenia."
Ref.: "Surviving Schizophrenia: A Family Manual", Dr. E. Fuller Torrey, Revised Edition (C)1988 Harper and Row ISBN 0-06-096249-6.
Hdescartes (talk) 16:09, 9 May 2009 (UTC)hdescartes
- I am not a fan of further reading sections. I figure if one isn't used in the referencing I am not averse to seeing it not mentioned, and I'd not complain if the sectnio were removed. Will need to ceck on MOS and consensus on that. Casliber (talk · contribs) 20:51, 9 May 2009 (UTC)
- Childhood schizophrenia is a rare disorder and is described well in this popular online source reviewed by psychiatrists for accuracy. —Preceding unsigned comment added by 71.254.200.174 (talk) 01:25, 25 May 2009 (UTC)
Yoga and link with Schizophernia
Thinking at a lower level of perception that can be explained physically and logically is considered social and acceptable, but the higher level of perception of an individual is considered unusual. This altered state of mind which it is unable to have commuinication with mass minds is Schizophernia. Newton, Nash are only one of few known and popular examples who have had the ability to climb down from unique mind to mass minds. Other die or cause death by inability to return or die (leave the body) as they find a free state of choosing reality they are in comfort.
See page 20 Times of India New Delhi edition for title Kids bring mom home after 20 years jungle stay.
This proves that Schizophernia can be not a threat if such persons stay in forest and even animals have a respect for such an individual in deep meditation.
Life is not as simple as is known. —Preceding unsigned comment added by 123.239.106.205 (talk) 13:15, 24 May 2009 (UTC)
Schizophrenia etymology
Schizophrenia does not literally mean "I split" it means "Split Mind". —Preceding unsigned comment added by Mattyb54 (talk • contribs) 07:08, 25 May 2009 (UTC)
- I am not sure to which you are referring - the word pieces are discussed separately. Casliber (talk · contribs) 19:55, 29 May 2009 (UTC)
Unsourced additions
This edit adds text to existing text, based on a source where only the PMID is easily available. Is the new text really covered in that article? Does anyone have the full text to verify? In fact, is all of the text sourced to that article really in that article, since it's about speech and doesn't seem very broad, based on the PMID alone? Can someone check, and either remove or source this new text? This kind of text creep, that appears to be sourced but may not be, has to be watched. Regards, SandyGeorgia (Talk) 13:38, 29 May 2009 (UTC)
- I'll take a look. Actually anhedonia is a bit of a borderline one too. Casliber (talk · contribs) 19:56, 29 May 2009
(UTC)
Famous persons with schizophrenia
Many persons, including kings and presidents, had this disease.The article hasn't a list of persons with this disease.Agre22 (talk) 23:15, 31 May 2009 (UTC)agre22
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