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::Delete all the primary research and replace it with the one 2007 review. Add the conclusions of this review to the lead. That should correct things.] (] · ] · ]) 11:02, 19 January 2010 (UTC) | ::Delete all the primary research and replace it with the one 2007 review. Add the conclusions of this review to the lead. That should correct things.] (] · ] · ]) 11:02, 19 January 2010 (UTC) | ||
Partial cross posting Fringe Theories Notice Board: | |||
:::I would remind editors here that the core policy, ] and guideline, ] favour peer reviewed studies, and these are peer reviewed studies. Second, the studies are not being used to support a claim but are examples of research on a particular topic which is the topic of the article. No editor opinion trumps a policy, and especially a core policy nor does a guideline like the fringe theories guideline supercede a core policy. Finally, I would assume that in advising deletion of all of the studies editors here will have read the studies or at least looked at the abstracts.(] (]) 14:55, 19 January 2010 (UTC)) |
Revision as of 14:55, 19 January 2010
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Surgical retractors
Would you be willing to have external links to 27 articles on the design and action of surgical retractors with photographs and descriptions of 20 different retractors? eg http://www.wikisurgery.com/index.php?title=Retractors_11_Tissue_holding-_Littlewood These are on our website at Wikisurgery.com. We have established external links to Misplaced Pages in the past and have had great interest from wikipedia users. I hope I have not transgressed any rules with this approach. Michael Harpur Edwards (talk)Michael Harpur Edwards (talk) 17:30, 2 January 2010 (UTC)
- Thank you for asking here: we encourage making an approach as you have. My first thought was no, because of our policy on external links, section Links normally to be avoided: "Any site that does not provide a unique resource beyond what the article would contain if it became a featured article". Having taken a good look at the site, I would ask the question "Could the material be incorporated into Misplaced Pages?". The answer is unclear to me, since the text on the WikiSurgery site is apparently "available under the terms of the GNU Free Documentation License", but the page on copyrights is empty. In addition, there is no copyright information for the images, although TinEye doesn't find them elsewhere. On the other hand, I can see value in the Wikisurgery site, so I would be tempted to agree with making links from our articles, as long as we can be sure we're not linking to a website containing copyright violations. Until we can verify the copyright terms of the text and images on WikiSurgery, I'd suggest we should wait before adding these as external links. --RexxS (talk) 19:20, 2 January 2010 (UTC)
- I can't imagine any single article benefiting from 27 separate links. WhatamIdoing (talk) 21:36, 2 January 2010 (UTC)
- Thank you very much for your comprehansive replies. I wrote all the text and made all the images. I hold the copyright for all of them and all the other text and images on the basic surgical skills program on wikisurgery. Will that be enough or would you prefer more formal evidence? About the 27 articles, a single link to the introductory article (http://www.wikisurgery.com/index.php?title=Retractors_04_Introduction) would lead the wikipedia user to all the others.Michael Harpur Edwards (talk)Michael Harpur Edwards (talk) 17:35, 5 January 2010 (UTC)
- I am no copyright expert, but I don't understand how you could "hold" the copyright to all of that content given this statement (and no apparent exceptions for the content in question) that it's under the GNU FDL. Based on the that copyleft provision, portions of wikisurgery could be copied to wikipedia as long as there is attribution, couldn't they? That might lead to more legible content on WP than a bunch of links. -- Scray (talk) 02:13, 6 January 2010 (UTC)
- The reason that Michael Harpur Edwards can claim to hold the copyrights at present is that he appears to be the only contributor (so far) on WikiSurgery, as a quick look at a few page histories shows (assuming that 'Michael edwards' and 'M h edwards' are synonymous). I doubt that content imported from there would pass WP:SPS, so if we felt that the images were useful, then an external link would really be the best solution. I'm leaning toward accepting MHE's word that we would not linking to copyvios, and recommending that we encourage inserting the external link(s). --RexxS (talk) 05:53, 6 January 2010 (UTC)
- May I take it from your discussions that you would be happy for me to insert an external link from Wikisurgery to the Misplaced Pages article on Retractors (Medical)? Please look at this article Retractor (medical) to check the link is OK with you? Michael Harpur Edwards (talk) 12:35, 12 January 2010 (UTC)
- Not everyone is going to agree 100% of the time, but the test is always "Does it improve the article?". In my very humble opinion, your external link improves that article. Thanks for taking the time to discuss this beforehand. --RexxS (talk) 17:02, 12 January 2010 (UTC)
Magnet therapy
It appears that a fast acting SPA is totally rewriting the article using primary research and slurring the distinction between unproven alternative medicine usage and proven mainstream usage. See the thread here:
Brangifer (talk) 17:04, 3 January 2010 (UTC)
- I don't remember if this topic was regarding DC fields ( IIRC the bone things were static currents, not sure about magnet stuff), but here is an interesting result,
http://www.ncbi.nlm.nih.gov/pubmed/20061638 of course cancer and stimulation are not mutually exclusive. In the absence of good causal arguments, you will get all kinds of confusing results because you can't control all the ( unknown ) variables and have to hope they just cancel out in larger placebo controlled trials. Nerdseeksblonde (talk) 12:28, 12 January 2010 (UTC)
Warburg's Tincture
Hi. I recently created and originated an article on Misplaced Pages about Warburg's Tincture. I'm writing here to enquire if the article should added to the Medicine WikiProject? I feel Warburg's Tincture is important in the history of medicine.--Roland Sparkes (talk) 18:11, 5 January 2010 (UTC)
- It is directly related to medicine, if you feel the same way, be bold and add the WP:MED banner on the discussion page without consulting anyone. Chances are, you will be correct. If you are not, it will be corrected with no strike against you. Tyrol5 18:19, 5 January 2010 (UTC)
- Done WhatamIdoing (talk) 18:24, 5 January 2010 (UTC)
- I also made a few changes to the formatting; you might like to look them over and copy the style. Also, WP:MEDMOS#Drugs might interest you. WhatamIdoing (talk) 18:32, 5 January 2010 (UTC)
I have expanded and improved this article a lot more now. Please can the article quality rating be reviewed. Thanks--Roland Sparkes (talk) 10:22, 8 January 2010 (UTC)
Hi. Please can people advise how the article Warburg's Tincture can be improved? I don't know that I can improve it any more. I don't come form a medical or science background. Thanks--Roland Sparkes (talk) 00:09, 15 January 2010 (UTC)
Regarding senile keratosis
Does the term senile keratosis refer to actinic keratosis or seborrheic keratosis? ---kilbad (talk) 18:41, 6 January 2010 (UTC)
- Senile keratosis is not a term that I'm particularly aware of. According to Weedon's Skin Pathology (3rd Ed), Seb K may also be known as senile wart, amongst other things, so this could be a candidate. I call actinic keratosis solar keratosis, and these do appear most often on the sun -exposed skin of older people, but they can also occur in younger solarium users. The two are obviously quite different and if I was going to use the term senile keratosis, I'd be more likely to apply it to a benign condition than a premalignant one. Cheers, Mattopaedia 04:31, 9 January 2010 (UTC)
- Ok, I am changing the redirect, based on your feedback and Bolognia, to senile keratosis --> actinic keratosis. ---kilbad (talk) 21:35, 9 January 2010 (UTC)
Book:Prostate
I've just created this book, but I'm not prostate expert. So if someone could quickly check if I haven't forgotten something, that would be great. Thanks. Headbomb {κοντριβς – WP Physics} 17:39, 9 January 2010 (UTC)
Brainstorming
I would like to have a list of dermatologists after which a cutaneous condition has been named. Restated, if a condition has been named after someone, that person is included in the list. I think this would be a nice reference for people. Do you think this would be ok? If so, what would you name the list? ---kilbad (talk) 21:39, 9 January 2010 (UTC)
- To answer a question you didn't ask, "how would you generate this list?" I would attempt to use some pubmed scripts to look at derma abstracts and find uncommon words, pref capitalized terms not starting sentences. Nerdseeksblonde (talk) 21:44, 9 January 2010 (UTC)
- Well, I will get most of them from the list of cutaneous conditions which is probably six months from being near comprehensive for cutaneous condition names/synonyms. But what should the list be titled? ---kilbad (talk) 21:53, 9 January 2010 (UTC)
- ], or ] if you want it to be intelligible to students and English-language learners. WhatamIdoing (talk) 22:36, 9 January 2010 (UTC)
- Are you thinking of something like WhoNamedIt.com Eponyms in category: Skin - dermatology? You know, when it has been done already, and better than one could possibly imagine achieving here, it seems a bit pointless to repeat the exercise. More useful IMO would be to write short encyclopaedic articles about these physicians than to just list them.
Category:Telehealth
I discovered a new category, Category:Telehealth, and was unsure whether it is a good idea ... so I listed it at Misplaced Pages:Categories for discussion/Log/2010 January 10#Category:Telehealth. Your contributions to the discussion would be welcome. --BrownHairedGirl (talk) • (contribs) 23:15, 10 January 2010 (UTC)
Anti-NMDA receptor encephalitis
Started Anti-NMDA receptor encephalitis, help is welcomed. Cheers, --CopperKettle 18:05, 11 January 2010 (UTC)
- Thanks for working on that - it looks good (and as recently described entity, there may not be much more to add for now). MastCell 18:14, 11 January 2010 (UTC)
- here are the citations for 20 most recent pubmed hits that mention nmda and encephalitis,
Poloni, C; Ricotti, V; King, MD; Perez, ER; Mayor-Dubois, C; Haenggeli, CA; Deonna, T (23-Dec-2009). "Severe childhood encephalopathy with dyskinesia and prolonged cognitive disturbances: evidence for anti-N-methyl-d-aspartate receptor encephalitis". Developmental medicine and child neurology: -. doi:10.1111/j.1469-8749.2009.03542.x. PMC 10.1111/j.1469-8749.2009.03542.x. PMID 20041934. {{cite journal}}
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Graus, F; Dalmau, J (25-Dec-2009). "Antibodies and neuronal autoimmune disorders of the CNS". Journal of neurology: -. doi:10.1007/s00415-009-5431-9. PMC 10.1007/s00415-009-5431-9. PMID 20035430. {{cite journal}}
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Iizuka, T (Nov-2009). "". Rinshō shinkeigaku = Clinical neurology. 49 (11): 774–8. PMID 20030207. {{cite journal}}
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Zandi, MS; Follows, G; Moody, AM; Molyneux, P; Vincent, A (8-Dec-2009). "Limbic encephalitis associated with antibodies to the NMDA receptor in Hodgkin lymphoma". Neurology. 73 (23): 2039–40. doi:10.1212/WNL.0b013e3181c55e9b. PMC 10.1212/WNL.0b013e3181c55e9b. PMID 19996080. {{cite journal}}
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de Broucker, T (24-Nov-2009). "". Medecine et maladies infectieuses: -. doi:10.1016/j.medmal.2009.10.013. PMC 10.1016/j.medmal.2009.10.013. PMID 19942390. {{cite journal}}
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Lebas, A; Didelot, A; Honnorat, J; Tardieu, M (15-Oct-2009). "Expanding Spectrum of Encephalitis With NMDA Receptor Antibodies in Young Children". Journal of child neurology: -. doi:10.1177/0883073809343319. PMC 10.1177/0883073809343319. PMID 19833974. {{cite journal}}
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Masuda, T; Ishibashi, M; Ito, M; Takahashi, Y; Kumamoto, T (Aug-2009). "". Rinshō shinkeigaku = Clinical neurology. 49 (8): 483–7. PMID 19827598. {{cite journal}}
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Parratt, KL; Lewis, SJ; Dalmau, J; Halmagyi, GM; Spies, JM (7-Sep-2009). "Acute psychiatric illness in a young woman: an unusual form of encephalitis". The Medical journal of Australia. 191 (5): 284–6. PMID 19740054. {{cite journal}}
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Bayreuther, C; Dellamonica, J; Borg, M; Bernardin, G; Thomas, P (Sep-2009). "Complex partial status epilepticus revealing anti-NMDA receptor encephalitis". Epileptic disorders : international epilepsy journal with videotape. 11 (3): 261–5. doi:10.1684/epd.2009.0266. PMC 10.1684/epd.2009.0266. PMID 19736168. {{cite journal}}
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Gable, MS; Radner, A; Tilley, DH; Lee, B; Dyner, L; Collins, A; Dengel, A; Dalmau, J; Glaser, CA (29-Aug-2009). "Anti-NMDA receptor encephalitis: report of ten cases and comparison with viral encephalitis". European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology: -. doi:10.1007/s10096-009-0799-0. PMC 10.1007/s10096-009-0799-0. PMID 19718525. {{cite journal}}
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Labate, A; Vincent, A; Gambardella, A; Piane, EL; Cianci, V; Aguglia, U (Sep-2009). "Anti-NMDA receptor encephalitis: a video case report". Epileptic disorders : international epilepsy journal with videotape. 11 (3): 267–9. doi:10.1684/epd.2009.0268. PMC 10.1684/epd.2009.0268. PMID 19713171. {{cite journal}}
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Splinter, WM (Sep-2009). "Anti-NMDA receptor antibodies encephalitis". Paediatric anaesthesia. 19 (9): 911–3. doi:10.1111/j.1460-9592.2009.03085.x. PMC 10.1111/j.1460-9592.2009.03085.x. PMID 19691699. {{cite journal}}
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Tüzün, E; Baehring, JM; Bannykh, S; Rosenfeld, MR; Dalmau, J (14-Aug-2009). "Evidence for antibody-mediated pathogenesis in anti-NMDAR encephalitis associated with ovarian teratoma". Acta neuropathologica: -. doi:10.1007/s00401-009-0582-4. PMC 10.1007/s00401-009-0582-4. PMID 19680671. {{cite journal}}
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Ichiyama, T; Matsushige, T; Kajimoto, M; Fukunaga, S; Furukawa, S (Nov-2009). "Serum matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 levels in non-herpetic acute limbic encephalitis". Journal of neurology. 256 (11): 1846–50. doi:10.1007/s00415-009-5207-2. PMC 10.1007/s00415-009-5207-2. PMID 19672673. {{cite journal}}
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Florance, NR; Lam, C; Szperka, C; Zhou, L; Ahmad, S; Campen, CJ; Moss, H; Peter, N; Gleichman, AJ; Glaser, CA; Lynch, DR; Rosenfeld, MR; Dalmau, J (Jul-2009). "Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in children and adolescents". Annals of neurology. 66 (1): 11–8. doi:10.1002/ana.21756. PMC 10.1002/ana.21756. PMID 19670433. {{cite journal}}
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De Nayer, AR; Sindic, CJ (15-Sep-2009). "A subacute behavioral disorder in a female adolescent. Autoimmune anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma". Biological psychiatry. 66 (6): e13-4. doi:10.1016/j.biopsych.2009.04.031. PMC 10.1016/j.biopsych.2009.04.031. PMID 19539270. {{cite journal}}
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Iizuka, T (Mar-2009). "". Rinsho byori. The Japanese journal of clinical pathology. 57 (3): 252–61. PMID 19363996. {{cite journal}}
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Sakuma, H (Aug-2009). "Acute encephalitis with refractory, repetitive partial seizures". Brain & development. 31 (7): 510–4. doi:10.1016/j.braindev.2009.02.010. PMC 10.1016/j.braindev.2009.02.010. PMID 19327924. {{cite journal}}
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Sas, AR; Smothers, CT; Woodward, J; Tyor, WR (25-Mar-2009). "Interferon-alpha causes neuronal dysfunction in encephalitis". The Journal of neuroscience : the official journal of the Society for Neuroscience. 29 (12): 3948–55. doi:10.1523/JNEUROSCI.5595-08.2009. PMC 10.1523/JNEUROSCI.5595-08.2009. PMID 19321791. {{cite journal}}
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Kataoka, H; Taoka, T; Ueno, S (15-Apr-2009). "Reduced N-acetylaspartate in the basal ganglia of a patient with anti-NMDA receptor encephalitis". Movement disorders : official journal of the Movement Disorder Society. 24 (5): 784–6. doi:10.1002/mds.22167. PMC 10.1002/mds.22167. PMID 19217070. {{cite journal}}
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Nerdseeksblonde (talk) 19:11, 11 January 2010 (UTC)
Colitis-X
Colitis-X is a new article nominated for DYK, written by an editor who does not usually write medical articles. I have given it a twice over but it needs more. One important issue remaining is that some of the sources are case reports. Are there no review articles? --Una Smith (talk) 07:03, 12 January 2010 (UTC)
- Ouch. I have been warned to clear out or I will be blocked. --Una Smith (talk) 03:18, 14 January 2010 (UTC)
- I'm sorry to hear that this is turning into a personalized dispute. The reactions on your talk page are intriguing: one editor wants to talk sense about the misuse of sources, and another wants to talk about past problems.
- However, the condition appears to be a horses-only veterinary issue, so you might want to post at WT:WikiProject Veterinary medicine. WhatamIdoing (talk) 08:50, 14 January 2010 (UTC)
Cephalalgia free online until 31st March 2010
Cephalalgia, the journal of the International Headache Society, has moved to SAGE Publications and the entire archive from 1981 - today is free full text online until 31st March 2010. http://cep.sagepub.com/ --Friedrich K. (talk) 14:11, 12 January 2010 (UTC)
Red yeast rice and 'statin' drugs
An editor has been doing quite a bit of work on revamping the red yeast rice article. I don't know enough about this subject to do much about it, but would like to see more eyes on the situation. It is especially the editor's COI that concerns me. He uses some red flag terminology (implying scientific evidence for alternative medicine, which would make it mainstream and no longer "alternative"). Here are some links to read:
- David notMD (talk · contribs · deleted contribs · logs · filter log · block user · block log)
- "Evidence-based science in support of complementary and alternative medicine, with focus on dietary supplements and functional foods. PhD in nutritional biochemistry; 25 years working in industry; currently a science consultant to companies wanting to make health claims for their products."
Note that I'm not implying any wrongdoing or bad faith on the part of this editor, just concerns that the article might be skewed in a way that promotes alternative medicine in an improper manner. Please take a look at the formatting, content, and especially references in light of WP:MEDRS, WP:Fringe and WP:Weight. -- Brangifer (talk) 01:57, 13 January 2010 (UTC)
- Here are the 20 most recent pubmed cites that mention both terms, I'd put it on talk page but trying to get people to use my tool for this. You can copy or move these to talk page and discuss each for inclusion or balance of prominence etc.
Tsai, RL; Pan, TM (17-Dec-2009). "Red Mold Rice Mitigates Oral Carcinogenesis in 7,12-Dimethyl-1,2-Benzanthracene-induced Oral Carcinogenesis in Hamster". Evidence-based complementary and alternative medicine : eCAM: -. doi:10.1093/ecam/nep215. PMC 10.1093/ecam/nep215. PMID 20019075. {{cite journal}}
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Gao, X; Pashkov, I; Sawaya, MR; Laidman, J; Zhang, W; Cacho, R; Yeates, TO; Tang, Y (30-Oct-2009). "Directed evolution and structural characterization of a simvastatin synthase". Chemistry & biology. 16 (10): 1064–74. doi:10.1016/j.chembiol.2009.09.017. PMC 10.1016/j.chembiol.2009.09.017. PMID 19875080. {{cite journal}}
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Barrios-González, J (10-Oct-2009). "Biotechnological production and applications of statins". Applied microbiology and biotechnology: -. doi:10.1007/s00253-009-2239-6. PMC 10.1007/s00253-009-2239-6. PMID 19820926. {{cite journal}}
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Sakai, K; Nihira, T (Dec-2009). "Identification of mokB involved in monacolin K biosynthesis in Monascus pilosus". Biotechnology letters. 31 (12): 1911–6. doi:10.1007/s10529-009-0093-3. PMC 10.1007/s10529-009-0093-3. PMID 19693441. {{cite journal}}
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Klimek, M; Ogunkanmi, A (Jun-2009). "Safety and Efficacy of Red Yeast Rice (Monascus purpureus) as an Alternative Therapy for Hyperlipidemia". P & T : a peer-reviewed journal for formulary management. 34 (6): 313–27. PMID 19572049. {{cite journal}}
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Xie, X; Xu, W; Dorrestein, PC; Tang, Y (24-Jun-2009). "Acyltransferase mediated polyketide release from a fungal megasynthase". Journal of the American Chemical Society. 131 (24): 8388–9. doi:10.1021/ja903203g. PMC 10.1021/ja903203g. PMID 19530726. {{cite journal}}
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Grieco, A; Pompili, M; Biolato, M; Vecchio, FM; Grattagliano, I; Gasbarrini, G (Jun-2009). "Acute hepatitis caused by a natural lipid-lowering product: when "alternative" medicine is no "alternative" at all". Journal of hepatology. 50 (6): 1273–7. doi:10.1016/j.jhep.2009.02.021. PMC 10.1016/j.jhep.2009.02.021. PMID 19398239. {{cite journal}}
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Hong, MY; Zhang, Y; Heber, D (Dec-2008). "Chinese red yeast rice versus lovastatin effects on prostate cancer cells with and without androgen receptor overexpression". Journal of medicinal food. 11 (4): 657–66. doi:10.1089/jmf.2007.0702. PMC 10.1089/jmf.2007.0702. PMID 19053857. {{cite journal}}
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Xie, X; Gao, X; Guerrero, JL; Yeates, TO; Tang, Y (1-Jan-2009). "Rational improvement of simvastatin synthase solubility in Escherichia coli leads to higher whole-cell biocatalytic activity". Biotechnology and bioengineering. 102 (1): 20–8. doi:10.1002/bit.22028. PMC 10.1002/bit.22028. PMID 18988191. {{cite journal}}
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Yang, Z (Mar-2008). "". Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 24 (3): 349–54. PMID 18589807. {{cite journal}}
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Chen, YP; Liaw, LL; Wang, CL; Chen, IC; Wu, WJ; Wu, MD; Yuan, GF (23-Jul-2008). "Cloning and characterization of monacolin K biosynthetic gene cluster from Monascus pilosus". Journal of agricultural and food chemistry. 56 (14): 5639–46. doi:10.1021/jf800595k. PMC 10.1021/jf800595k. PMID 18578535. {{cite journal}}
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Lee, CL; Pan, TM (Jul-2008). "Red mold rice extract represses amyloid beta peptide-induced neurotoxicity via potent synergism of anti-inflammatory and antioxidative effect". Applied microbiology and biotechnology. 79 (5): 829–41. doi:10.1007/s00253-008-1480-8. PMC 10.1007/s00253-008-1480-8. PMID 18438657. {{cite journal}}
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Lee, CL; Wang, JJ; Pan, TM (26-Dec-2007). "A simple and rapid approach for removing citrinin while retaining monacolin K in red mold rice". Journal of agricultural and food chemistry. 55 (26): 11101–8. doi:10.1021/jf071640p. PMC 10.1021/jf071640p. PMID 18047280. {{cite journal}}
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Wang, TH (2007). "Monascus rice products". Advances in food and nutrition research. 53: 123–59. doi:10.1016/S1043-4526(07)53004-4. PMC 10.1016/S1043-4526(07)53004-4. PMID 17900498. {{cite journal}}
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Suh, SH; Mah, JH; Lee, W; Byun, MW; Hwang, HJ (Sep-2007). "Optimization of production of monacolin K from gamma-irradiated Monascus mutant by use of response surface methodology". Journal of medicinal food. 10 (3): 408–15. doi:10.1089/jmf.2006.097. PMC 10.1089/jmf.2006.097. PMID 17887933. {{cite journal}}
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Hong, MY; Zhang, Y; Heber, D (Jul-2008). "Anticancer effects of Chinese red yeast rice versus monacolin K alone on colon cancer cells". The Journal of nutritional biochemistry. 19 (7): 448–58. doi:10.1016/j.jnutbio.2007.05.012. PMC 10.1016/j.jnutbio.2007.05.012. PMID 17869085. {{cite journal}}
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Lee, CL; Wang, JJ; Pan, TM (22-Aug-2007). "Red mold dioscorea has greater hypolipidemic and antiatherosclerotic effect than traditional red mold rice and unfermented dioscorea in hamsters". Journal of agricultural and food chemistry. 55 (17): 7162–9. doi:10.1021/jf071293j. PMC 10.1021/jf071293j. PMID 17655247. {{cite journal}}
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Lee, CL; Wang, JJ; Pan, TM (8-Aug-2007). "Improving the ratio of monacolin K to citrinin production of Monascus purpureus NTU 568 under dioscorea medium through the mediation of pH value and ethanol addition". Journal of agricultural and food chemistry. 55 (16): 6493–502. doi:10.1021/jf0711946. PMC 10.1021/jf0711946. PMID 17636932. {{cite journal}}
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Xie, X; Tang, Y (Jul-2007). "Improving simvastatin bioconversion in Escherichia coli by deletion of bioH". Metabolic engineering. 9 (4): 379–86. doi:10.1016/j.ymben.2007.05.006. PMC 10.1016/j.ymben.2007.05.006. PMID 17625941. {{cite journal}}
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Xie, X (Apr-2007). "Efficient synthesis of simvastatin by use of whole-cell biocatalysis". Applied and environmental microbiology. 73 (7): 2054–60. doi:10.1128/AEM.02820-06. PMC 10.1128/AEM.02820-06. PMID 17277201. {{cite journal}}
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Nerdseeksblonde (talk) 02:09, 13 January 2010 (UTC)
- Nerd I think that if you added a basic GUI to it and perhaps also some options eg restricting searches to a range of years and so forth it could become quite a popular tool. I have added it to my userpage though for when it comes in handy.--Literaturegeek | T@1k? 22:45, 14 January 2010 (UTC)
Weight loss
..needs a few eyes. It has accumulated vandalcruft and spam. Now semi-protected for a while.LeadSongDog come howl 05:12, 13 January 2010 (UTC)
- Yes agree this is a poor quality page. Not sure how to fit it in with the rest of the obesity topic. The management section of obesity is well done IMO :-) but I might have a COI. Maybe redirect intentional weight loss to the management section of obesity and change the name of the page to unintentional weight loss? This would reduce duplication of content. Doc James (talk · contribs · email) 22:50, 14 January 2010 (UTC)
Surgery task force
I proposed the surgery task force here. I thought that I might bring it up here to stir up some interest. Surgery is a vast branch of medicine that requires comprehensive coverage on Misplaced Pages. If interested, add your self to the list here. Thanks. Tyrol5 01:18, 14 January 2010 (UTC)
A new ambitious user
User:Immunize (contribs) has been creating new unreferenced medical articles and has been making unreferenced additions to existing medical articles. I have been trying to get this user to cite sources, but he is reluctant to take my advice. Also, the user's grammar and punctuation need help. I simply cannot keep up with this user's edits and I also am nowhere near an expert in the topics in which he is contributing. Can someone take a look at this person's edits? Regards, PDCook (talk) 15:11, 14 January 2010 (UTC)
- Yes looks like he / she could be a very good contributor if he / she referenced what they wrote. Will look into it.Doc James (talk · contribs · email) 22:42, 14 January 2010 (UTC)
- It looks like the contributor's work comes from Emedicine. Is that a reliable source? It looks like the articles there are written by MDs or PhDs and sources are cited. PDCook (talk) 22:51, 14 January 2010 (UTC)
- It is sort of reliable but is not a preferred reference source. But to reference the actual research / review or a more stable source such as a text book.Doc James (talk · contribs · email) 22:53, 14 January 2010 (UTC)
- Apparently emedicine is preferred over actual text books. ---kilbad (talk) 23:17, 14 January 2010 (UTC)
- I do not see were it says this? Doc James (talk · contribs · email) 23:21, 14 January 2010 (UTC)
- I was being facetious. Sorry... ---kilbad (talk) 00:16, 15 January 2010 (UTC)
- I do not see were it says this? Doc James (talk · contribs · email) 23:21, 14 January 2010 (UTC)
- Well I cited Emedicine in a few of Immunize's articles, as it is better than nothing. I found a couple of primary articles and reviews, but most were in journals my University did not have an online subscription to, so I figured it was better off left to someone who can read them deal with. Thanks, PDCook (talk) 23:24, 14 January 2010 (UTC)
- Apparently emedicine is preferred over actual text books. ---kilbad (talk) 23:17, 14 January 2010 (UTC)
- It is sort of reliable but is not a preferred reference source. But to reference the actual research / review or a more stable source such as a text book.Doc James (talk · contribs · email) 22:53, 14 January 2010 (UTC)
- It looks like the contributor's work comes from Emedicine. Is that a reliable source? It looks like the articles there are written by MDs or PhDs and sources are cited. PDCook (talk) 22:51, 14 January 2010 (UTC)
- Yes looks like he / she could be a very good contributor if he / she referenced what they wrote. Will look into it.Doc James (talk · contribs · email) 22:42, 14 January 2010 (UTC)
- I'm still cleaning up a lot of this user's issues. He doesn't really listen to my warnings very well. Can someone else please give him some advice? I fear this may end up on ANI if it doesn't get better. PDCook (talk) 16:32, 15 January 2010 (UTC)
GA reviews
I am currently doing two GA reviews in which editors have requested further opinions. Wondering if someone could take a look at Self-harm and Good Samaritan law and give us your opinions? Doc James (talk · contribs · email) 19:21, 14 January 2010 (UTC)
HNPCC/Lynch syndrome
The HNPCC talk page has a move dicussion on it that seems to have gone dead. I was thinking about doing some histology work on the article and found this long discussion about the relative merits of calling the page Lynch Syndrome, versus HNPCC. I found this article, , which is a recent review and recommends that there is supprt for calling the condition LS in favour of HNPCC. Is anyone still interested in this move discussion? Mattopaedia 01:32, 15 January 2010 (UTC)
red hot chili pepprs, alt/compl/herbal labels
I guess this is why I hesitate to dismiss or trivialize herbal or folk lore stuff until better evidence is in. http://www.nature.com/onc/journal/v29/n2/abs/onc2009335a.html "Capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide) is an ingredient of chili peppers with inhibitory effects against cancer cells of different origin." I think there can be a tendency here to put science into box somewhere but careful observation anywhere can be important. Personally, it wouldn't surprise me if you may be able to take peppers, garlic, and citric acid and make therapaeutic food ( if you can get ph up was per the "alkaline diet" folks). Citric acid would be interesting as that is a case where ( possible, if recent conjecture is right ) that folk lore about fruit juice could turn out to be right but in fact everyone was distracted by the anti-oxidants ( ascorbic acid). Nerdseeksblonde (talk) 15:10, 15 January 2010 (UTC)
- You need a prescription for this stuff in Canada. I prescribe a cream of it frequently. Would not call it folk lore as it use is based on randomized trials and is an integral part of medicine. ASA comes from the willow tree but a cardiologist is not the same as a naturalpath.
- The research you provide appears to be done by physicians / medical researchers which makes it medicine. Also it has in no way reached clinical utility.Doc James (talk · contribs · email) 17:40, 15 January 2010 (UTC)
- I'm big on MOA and background myself but in terms of describing what is thought to work, there seems to be a tendency to ignore anything that doesn't come along with credentials. OF course, we need well controlled test and MOA but that doesn't mean that anecdotes would mislead the reader about state of human understanding or what may really work. If you were a PhD looking for leads, sometimes talking to a Shaman can be helpful for ideas even if his thoughts don't prove to be right or systematic. Nerdseeksblonde (talk) 17:50, 15 January 2010 (UTC)
- Stuff like this might belong under a section on research but no were else in the article. And definitely not in a treatment / management section. What is MOA by the way? Doc James (talk · contribs · email) 19:34, 15 January 2010 (UTC)
- Red Hot Chili Peppers, out of scope, see WP:WP MUSIC. MOA is mode of action. Tim Vickers (talk) 19:43, 15 January 2010 (UTC)
- I'm big on MOA and background myself but in terms of describing what is thought to work, there seems to be a tendency to ignore anything that doesn't come along with credentials. OF course, we need well controlled test and MOA but that doesn't mean that anecdotes would mislead the reader about state of human understanding or what may really work. If you were a PhD looking for leads, sometimes talking to a Shaman can be helpful for ideas even if his thoughts don't prove to be right or systematic. Nerdseeksblonde (talk) 17:50, 15 January 2010 (UTC)
- Wiki is not a how-to self medicate publication, there is no treatment recommendation section. But, if you are describing what is thought in various communities and feel like you want to inflict good intentions on the article to save the reader, I'm just suggesting that you calm down a bit. In terms of merit, when the jury is out all you know is that it is out. If you try to leave stuff out, it is unlikely that will help people who only know about things from Suzanne Summers and Oprah. Do you want people listening to Oprah or do you at least want to present all views, including research literature, and put them into a complete context? Imagine someone coming here and finding, "gee, wikipedia didn't even know that oprah covered this in great detail." Nerdseeksblonde (talk) 19:58, 15 January 2010 (UTC)
- No, not really: I don't generally want early research work represented in disease articles. WP:CRYSTAL stuff is generally not WP:DUE, even if Oprah talked about it. I also don't want religious views on what we'll find on the Moon to be added to Moon, or common views about women's driving skills to be added to auto accident, or popular superstitions about walking underneath ladders to be added to Ladder. If, on the other hand, you can get me a good source about what is on the Moon, or a good study about how gender differences affect accident rates, or how often ladder-related accidents happen, then I'm all for it. That's encyclopedic information; what inexpert or uneducated people believe is not.
- Our general rule of thumb is that if you don't have actual human trials, then it's not worth mentioning, and if it's a future regulated therapeutic, we'd rather wait until it's in Phase III trials, not merely first-in-human tests. (Note, please that this rule of thumb is biased against pharmaceutical companies.) There might be exceptions (e.g., an article about "Research on ____" might take a more expansive approach), but I'm quite satisfied with our general rule of thumb. WhatamIdoing (talk) 06:37, 16 January 2010 (UTC)
- The inclusion of material would depend on the topic but ignoring research or Oprah on many diseases would limit the scope of the article to an arbitrarily chosen community and not reflect what is generally known or thought. It is not crysal balling to say that " a lot of work is being done on various natually occuring products" or undue weight to mention that "many popular folk rememdies have been promoted" etc. An isolated research article may or may not merit inclusion in a given topic but I think your examples above are pushing the weight issue a bit. However, popular stories about ladder superstitions can have a place somewehere. What example of an article do you have that only mentions US FDA approved products in regards to a disease? I'm not even sure how you could possible write an article like this where there is both ongoing research and a history of folk rememdies. Nerdseeksblonde (talk) 13:21, 16 January 2010 (UTC)
- If it is well referenced ( ie nature ) adding it to a section on research may be important. What people do use a natural products may fit under the section on society and culture if appropriately worded. Added to a section on treatment is not appropriate. What sources is required depends on were it is going. Beliefs on stars is trivia and may belong on their own pages but not a on medical page.Doc James (talk · contribs · email) 21:28, 16 January 2010 (UTC)
- The inclusion of material would depend on the topic but ignoring research or Oprah on many diseases would limit the scope of the article to an arbitrarily chosen community and not reflect what is generally known or thought. It is not crysal balling to say that " a lot of work is being done on various natually occuring products" or undue weight to mention that "many popular folk rememdies have been promoted" etc. An isolated research article may or may not merit inclusion in a given topic but I think your examples above are pushing the weight issue a bit. However, popular stories about ladder superstitions can have a place somewehere. What example of an article do you have that only mentions US FDA approved products in regards to a disease? I'm not even sure how you could possible write an article like this where there is both ongoing research and a history of folk rememdies. Nerdseeksblonde (talk) 13:21, 16 January 2010 (UTC)
- Um, NSB, I did not say anything about "US FDA approved products". In fact, I explicitly named standards that are (1) independent of government approval and (2) always happen before government approval and (3) can be applied just as well to a natural product as to a regulated therapeutic. Perhaps you are not very familiar with the drug approval process? WhatamIdoing (talk) 22:18, 16 January 2010 (UTC)
- Generally negative results can be hard to dig up, depending on who sponsored the trial, and there have been attempts to make negative clinical trials better known but within this communityy of scientists, there is different treatment of data yoy like and don't like. The clinical trials you mention themselves are usually govt approved trials or did you mean trials suzanne somers did? Generally there is more weight on trials leading to approval unless someone benefits from advertising a given failure. My original point in posting this link is to calm down the militant folks who want to protect people from information. If nothing else, anecdotes and folk lore can eventuall be tested and making a reader aware of prominent folk lore can help him get a better idea of what may motivate things he find in research etc. I'm just suggesting there is no down side to the goal of the encyuclopedia, except I guess you could call some of this clutter or trivia. Observations of the resarch community tend to be better controlled and accurate and can be intergrated into more systmatic understanding (MOA) but are just as much anecdotal as folk lore in some cases. If you take something literally approaching a militant attitude, you still want to know your enemy and if you have faith that science will prevail, ultimately you can insert " as was shown to be danergous this folk lore is now discredited reminding people to listen to doctors "( Obviously you wouldn't reallyu editorialize like this but presumably you would convey that message to reader ) etc. Nerdseeksblonde (talk) 13:48, 17 January 2010 (UTC)
- Um, NSB, I did not say anything about "US FDA approved products". In fact, I explicitly named standards that are (1) independent of government approval and (2) always happen before government approval and (3) can be applied just as well to a natural product as to a regulated therapeutic. Perhaps you are not very familiar with the drug approval process? WhatamIdoing (talk) 22:18, 16 January 2010 (UTC)
Dysentery
I've decided to try to improve this article to at least a B or possibly GA. I think the main things that need improving are: history section, including past epidemics as well as cases in developing countries today; separate pathophysiology section - no real information about transmission now either; prevention, including vaccination (and possibly problems with supply in developing world); more sources needed; more distinction required between amoebic and bacillary; and an image, possibly one of the bacterium.
The reason I came here is because I know almost nothing about the disease, and everything I put in will be purely from what papers etc I can find. I don't think it's worth starting a PR on this now, so if anyone has any other suggestions, please make them known. I might not be able to do much next week though (so don't think I've forgotten if not much happens). Jhbuk (talk) 16:18, 15 January 2010 (UTC)
Article structure for pages pertaining to symptoms
We currently do not have a recommended structure for articles pertaining to symptoms. I am trying to address this and would appreciate input. Wikipedia_talk:Manual_of_Style_(medicine-related_articles)#Symptoms Doc James (talk · contribs · email) 06:04, 16 January 2010 (UTC)
Expert help needed
Hi, please could someone comment at the following discussion Talk:Self-harm#Map_of_self_inflicted_injuries. We are in need of expert comment on the use of DALY's to produce a worldmap on the self-harm page. The main concern being that the lay person will not understand the map. Many thanks, Jdrewitt (talk) 07:46, 16 January 2010 (UTC)
G-spot amplification
Someone here may want to look at that procedure, particularly if you have access to PMID 17766626. The wiki article looks a bit advertorial. Currently at AfD. Pcap ping 11:23, 16 January 2010 (UTC)
- Everything I need to know in life, I learned on Wiki. SandyGeorgia (Talk) 04:37, 17 January 2010 (UTC)
- I cleaned it up, if others want to have a look or try to expand if you have access to the sources listed. I hope I get a barnstar-- or something-- for now being the editor with the highest edit count on this topic. SandyGeorgia (Talk) 05:45, 17 January 2010 (UTC)
- Glad to be of help :-0 Pcap ping 09:05, 17 January 2010 (UTC)
Help with ketogenic diet on Main Page tomorrow (17th Jan)
I'd appreciate folk here adding this to their watch page and helping out with vandalism, etc. I'm going to be asleep for the initial hours of the 17th! Thanks. Colin° 17:59, 16 January 2010 (UTC)
- Congratulations on the FA. The first 90 minutes were pretty quiet... I hope that the rest of the day goes as well. A new editor has asked a question on the talk page that will be easier for someone that is familiar with the named sources to answer. WhatamIdoing (talk) 03:40, 17 January 2010 (UTC)
- I'm sure Colin will get to it (and the other pleasantries on the talk page) as soon as he wakes up. SandyGeorgia (Talk) 04:39, 17 January 2010 (UTC)
Violent patient
I am intending on start a page on this topic to deal with the medical approach to violence and agitation. Wondering what term I should us for the title? Here is a paper on the topic.
- Rossi J, Swan MC, Isaacs ED (2010). "The violent or agitated patient". Emerg. Med. Clin. North Am. 28 (1): 235–56, x. doi:10.1016/j.emc.2009.10.006. PMID 19945609.
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Doc James (talk · contribs · email) 02:17, 17 January 2010 (UTC)
- Would Violence (medicine) be better and redirect the above? I think so.Doc James (talk · contribs · email) 04:30, 17 January 2010 (UTC)
- Probably, since MEDMOS says something about "patient" vs. "individual" terminology. SandyGeorgia (Talk) 04:38, 17 January 2010 (UTC)
- Would Violence (medicine) be better and redirect the above? I think so.Doc James (talk · contribs · email) 04:30, 17 January 2010 (UTC)
- "Violence (medicine)" makes me think Physical trauma, e.g., how to treat survivors of violent crimes, which is not what you're aiming for. WhatamIdoing (talk) 04:50, 17 January 2010 (UTC)
- How about Managing violence in a medical environment? A little wordy but gets the point across... Doc James (talk · contribs · email) 05:00, 17 January 2010 (UTC)
- That would work for me. If we drop the "Managing", the article would more obviously apply to other aspects (such as causes). WhatamIdoing (talk) 05:37, 17 January 2010 (UTC)
- If we drop "managing", we're right back to Violence (medicine). SandyGeorgia (Talk) 05:42, 17 January 2010 (UTC)
- That would work for me. If we drop the "Managing", the article would more obviously apply to other aspects (such as causes). WhatamIdoing (talk) 05:37, 17 January 2010 (UTC)
- How about Managing violence in a medical environment? A little wordy but gets the point across... Doc James (talk · contribs · email) 05:00, 17 January 2010 (UTC)
- Violence in a medical environment is a little different from Violence (medicine) and I agree is better.Doc James (talk · contribs · email) 05:50, 17 January 2010 (UTC)
http://www.nice.org.uk/CG25 - this is the English/Welsh guideline for acute violence in the medical context. Hope you find it useful. JFW | T@lk 11:21, 17 January 2010 (UTC)
Curious..
..are there any lipid metabolism disorders that may present as a mild case of diabetes that is aggravated by lipid intake? Or any case of diabetes? --CopperKettle 16:41, 17 January 2010 (UTC)
- Do we mean the same thing when we say "lipid metabolism disorder"? I think of a purely genetic problem (i.e., enzyme mutation). There are all kinds of much more common things that are "aggravated" by "lipid intake" in some people, e.g., pancreatitis, gall bladder problems, hepatitis... WhatamIdoing (talk) 17:39, 17 January 2010 (UTC)
Article needs help
This article, Brittle asthma, has multiple issues I cannot find. Please leave me a talkback or reply on my page.--Microsoft 1000 Defender and Ruler of Cyberspace! 20:27, 17 January 2010 (UTC)
Merger
As far as I am aware sexual assault and rape are the same thing yet we have two large pages on them. Having a merge discussion here Talk:Rape#Merge_discussion Doc James (talk · contribs · email) 00:40, 18 January 2010 (UTC)
Poppers
I think the article should be tagged for this project. The lede seems POV in that these are largely untested and unregulated chemicals used recreationally and known to cause medical problems yet the article seems to glow about how harmless they are. Thoughts? -- Banjeboi 19:12, 18 January 2010 (UTC)
- The article has been a cesspit for awhile. I abandoned it a year or two ago after a proliferation of warring single-purpose accounts depressed me. It would probably be worthwhile to revisit it. MastCell 21:18, 18 January 2010 (UTC)
- ONe of those SPA's was, IMHO, Hank Wilson who seems to have been a lone activist trying to collect and distribute the scientific studies he found. He died last year at some point. The others have every appearance of selling the stuff. -- Banjeboi 03:50, 19 January 2010 (UTC)
- The recreational drug pages along with sex topics are some of Wikipedias most visited. They are also the most heavily vandalized. Both fall under WP:MED! Are we not lucky? Doc James (talk · contribs · email) 04:38, 19 January 2010 (UTC)
- Hank Wilson passed away at the end of 2008, and I do remember hearing that he had held on to the causation of poppers with AIDS/KS long after that was abandoned. Here's a bibliography attributed to him. I don't see anything in the article covering poppers use and increased STD risk due to vasodilation, although there is material on tie to increased high-risk behavior and on use with Viagra. With respect to the pages popularity, I've been working under the assumption that flagged revisions would eventually wind their to way to a lot of med articles at some point for that reason. -Optigan13 (talk) 04:47, 19 January 2010 (UTC)
- The recreational drug pages along with sex topics are some of Wikipedias most visited. They are also the most heavily vandalized. Both fall under WP:MED! Are we not lucky? Doc James (talk · contribs · email) 04:38, 19 January 2010 (UTC)
- ONe of those SPA's was, IMHO, Hank Wilson who seems to have been a lone activist trying to collect and distribute the scientific studies he found. He died last year at some point. The others have every appearance of selling the stuff. -- Banjeboi 03:50, 19 January 2010 (UTC)
Transcendental_Meditation
Can some project members review the use of medical sources in this article ? The basic issue is outlined at this FTN dissussion, and particularly this subthread. Abecedare (talk) 10:39, 19 January 2010 (UTC)
- Delete all the primary research and replace it with the one 2007 review. Add the conclusions of this review to the lead. That should correct things.Doc James (talk · contribs · email) 11:02, 19 January 2010 (UTC)
Partial cross posting Fringe Theories Notice Board:
- I would remind editors here that the core policy, WP:VERIFIABLE and guideline, WP:RS favour peer reviewed studies, and these are peer reviewed studies. Second, the studies are not being used to support a claim but are examples of research on a particular topic which is the topic of the article. No editor opinion trumps a policy, and especially a core policy nor does a guideline like the fringe theories guideline supercede a core policy. Finally, I would assume that in advising deletion of all of the studies editors here will have read the studies or at least looked at the abstracts.(olive (talk) 14:55, 19 January 2010 (UTC))