BOP reagent: Difference between revisions

Browse history interactively ← Previous edit Next edit →Content deleted Content addedVisual WikitextInline

Revision as of 21:14, 19 January 2011 editThe chemistds (talk \| contribs)Extended confirmed users5,761 edits Added PubChem, CSID, stdInChI, and stdInChIkey← Previous edit		Revision as of 21:24, 19 January 2011 edit undoCheMoBot (talk \| contribs)Bots141,565 edits Updating {{chembox}} (no changed fields - added verified revid - updated 'UNII_Ref', 'ChemSpiderID_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref', 'ChEMBL_Ref', 'KEGG_Ref') per Chem/Drugbox validation (Next edit →
Line 1:		Line 1:
	{{chembox		{{chembox
			\| verifiedrevid = 408850859
	\| ImageFile = BOP reagent.png		\| ImageFile = BOP reagent.png
	\| ImageSize =		\| ImageSize =
Line 7:		Line 8:
	\| CASNo = 56602-33-6		\| CASNo = 56602-33-6
	\| PubChem = 151348		\| PubChem = 151348
			\| ChemSpiderID_Ref = {{chemspidercite\|correct\|chemspider}}
	\| ChemSpiderID = 133386		\| ChemSpiderID = 133386
	\| SMILES = F(F)(F)(F)(F)F.n1nn(O(N(C)C)(N(C)C)N(C)C)c2ccccc12		\| SMILES = F(F)(F)(F)(F)F.n1nn(O(N(C)C)(N(C)C)N(C)C)c2ccccc12
			\| StdInChI_Ref = {{stdinchicite\|correct\|chemspider}}
	\| StdInChI=1S/C12H22N6OP.F6P/c1-15(2)20(16(3)4,17(5)6)19-18-12-10-8-7-9-11(12)13-14-18;1-7(2,3,4,5)6/h7-10H,1-6H3;/q+1;-1		\| StdInChI=1S/C12H22N6OP.F6P/c1-15(2)20(16(3)4,17(5)6)19-18-12-10-8-7-9-11(12)13-14-18;1-7(2,3,4,5)6/h7-10H,1-6H3;/q+1;-1
⚫	\| StdInChIKey = MGEVGECQZUIPSV-UHFFFAOYSA-N
			\| StdInChIKey_Ref = {{stdinchicite\|correct\|chemspider}}
		⚫	\| StdInChIKey = MGEVGECQZUIPSV-UHFFFAOYSA-N
	}}		}}
	\| Section2 = {{Chembox Properties		\| Section2 = {{Chembox Properties

Revision as of 21:24, 19 January 2011

BOP reagent
Names

IUPAC name Benzotriazole-1-yl-oxy-tris-(dimethylamino)-phosphonium hexafluorophosphate
Other names Castro's reagent
Identifiers
CAS Number	56602-33-6
3D model (JSmol)	Interactive image
ChemSpider	133386
ECHA InfoCard	100.054.782
PubChem CID	151348
CompTox Dashboard (EPA)	DTXSID60205170
InChI InChI=1S/C12H22N6OP.F6P/c1-15(2)20(16(3)4,17(5)6)19-18-12-10-8-7-9-11(12)13-14-18;1-7(2,3,4,5)6/h7-10H,1-6H3;/q+1;-1Key: MGEVGECQZUIPSV-UHFFFAOYSA-N
SMILES F(F)(F)(F)(F)F.n1nn(O(N(C)C)(N(C)C)N(C)C)c2ccccc12
Properties
Chemical formula	C₁₂H₂₂F₆N₆OP₂
Molar mass	442.281 g/mol
Appearance	White crystalline powder
Melting point	136 - 140 °C
Solubility in water	Partially soluble in cold water
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Y verify (what is ?) Infobox references

Chemical compound

BOP-reagent is a reagent commonly used in the synthesis of peptides. Its use is discouraged because coupling using BOP liberates HMPA which is carcinogenic, although for small scale use in an organic laboratory this is not a great disadvantage as it is in large scale industrial usage.

Misplaced Pages

BOP reagent: Difference between revisions

Revision as of 21:24, 19 January 2011

See also