Flutrimazole: Difference between revisions

Revision as of 00:40, 1 July 2011 editPeryeat (talk \| contribs)Extended confirmed users2,689 editsNo edit summary← Previous edit		Revision as of 02:08, 1 July 2011 edit undoCheMoBot (talk \| contribs)Bots141,565 edits Updating {{drugbox}} (changes to verified fields - added verified revid - updated 'ChEMBL_Ref', 'KEGG_Ref') per Chem/Drugbox validation (report errors Next edit →
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	{{drugbox		{{drugbox
			\| Verifiedfields = changed
	\| UNII_Ref = {{fdacite\|~~correct~~\|FDA}}		\| UNII_Ref = {{fdacite\|changed\|FDA}}
	\| UNII = 776S0UP252		\| UNII = 776S0UP252
	\| verifiedrevid = ~~400095163~~		\| verifiedrevid = 407238190
	\| drug_name = Flutrimazole		\| drug_name = Flutrimazole
	\| IUPAC_name = (''RS'')-1--1''H''-imidazole		\| IUPAC_name = (''RS'')-1--1''H''-imidazole
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	\| PubChem = 3401		\| PubChem = 3401
	\| DrugBank =		\| DrugBank =
			\| KEGG_Ref = {{keggcite\|correct\|kegg}}
	\| KEGG = D07193		\| KEGG = D07193
	\| C=22\|H=16\|F=2\|N=2		\| C=22\|H=16\|F=2\|N=2

Revision as of 02:08, 1 July 2011

Pharmaceutical compound

Flutrimazole
Clinical data

ATC code	G01AF18 (WHO)
Identifiers
IUPAC name (RS)-1--1H-imidazole
CAS Number	119006-77-8
PubChem CID	3401
ChemSpider	3284
UNII	776S0UP252
KEGG	D07193
CompTox Dashboard (EPA)	DTXSID30869622
ECHA InfoCard	100.170.770
Chemical and physical data
Formula	C₂₂H₁₆F₂N₂
Molar mass	346.373 g/mol g·mol
3D model (JSmol)	Interactive image
SMILES Fc1ccc(cc1)C(c2c(F)cccc2)(c3ccccc3)n4ccnc4
InChI InChI=1S/C22H16F2N2/c23-19-12-10-18(11-13-19)22(26-15-14-25-16-26,17-6-2-1-3-7-17)20-8-4-5-9-21(20)24/h1-16H Key:QHMWCHQXCUNUAK-UHFFFAOYSA-N
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Flutrimazole is a wide spectrum antifungal drug. It is used for the topical treatment of superficial mycoses of the skin. Flutrimazole is an imidazole derivative. It interferes with the synthesis of ergosterol by inhibiting the activity of the enzyme lanosterol-14-demethylase.

Arsenic compounds

Quinoline derivatives

Imidazoles	Metronidazole Clotrimazole Miconazole Econazole Ornidazole Isoconazole Tioconazole Ketoconazole Fenticonazole Azanidazole Propenidazole Butoconazole Omoconazole Oxiconazole Flutrimazole
Triazoles	Terconazole
Polyenes	Nystatin Natamycin Amphotericin B
Other	Ciclopirox Methylrosaniline

Other

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