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Revision as of 15:02, 21 March 2011 editCheMoBot (talk | contribs)Bots141,565 edits Updating {{chembox}} (changes to watched fields - updated 'UNII_Ref', 'ChEMBL_Ref', 'KEGG_Ref') per Chem/Drugbox validation (report errors or [[user talk:← Previous edit Revision as of 08:50, 9 August 2011 edit undoBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Script assisted update of identifiers for the Chem/Drugbox validation project (updated: 'ChEBI').Next edit →
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| CASNo = 59-56-3 | CASNo = 59-56-3
| PubChem = 65533 | PubChem = 65533
| SMILES = O=P(O)(OC1O((O)(O)1O)CO)O | ChEBI = 16077
| SMILES = O=P(O)(OC1O((O)(O)1O)CO)O
| MeSHName = glucose-1-phosphate | MeSHName = glucose-1-phosphate
}} }}

Revision as of 08:50, 9 August 2011

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Glucose 1-phosphate
Names
IUPAC name Glucose 1-phosphate
Identifiers
CAS Number
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.000.396 Edit this at Wikidata
MeSH glucose-1-phosphate
PubChem CID
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C6H13O9P/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13/h2-10H,1H2,(H2,11,12,13)/t2-,3-,4+,5-,6?/m1/s1Key: HXXFSFRBOHSIMQ-GASJEMHNSA-N
  • InChI=1/C6H13O9P/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13/h2-10H,1H2,(H2,11,12,13)/t2-,3-,4+,5-,6?/m1/s1Key: HXXFSFRBOHSIMQ-GASJEMHNBR
SMILES
  • O=P(O)(OC1O((O)(O)1O)CO)O
Properties
Chemical formula C6H13O9P
Molar mass 260.136
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkY verify (what is  ?) Infobox references
Chemical compound

Glucose 1-phosphate (also called cori ester) is a glucose molecule with a phosphate group on the 1'-carbon.

Reactions

Catabolic

In glycogenolysis, it is the direct product of the reaction in which glycogen phosphorylase cleaves off a molecule of glucose from a greater glycogen structure.

To be utilized in cellular catabolism it must first be converted to glucose 6-phosphate by the enzyme phosphoglucomutase. One reason that cells form glucose 1-phosphate instead of glucose during glycogen breakdown is that the very polar phosphorylated glucose cannot leave the cell membrane and so is marked for intracellular catabolism.

Anabolic

In glycogenesis, free glucose 1-phosphate can also react with UTP to form UDP-glucose, by using the enzyme UDP-glucose pyrophosphorylase. It can then return to the greater glycogen structure via glycogen synthase.

See also

Stub icon

This biochemistry article is a stub. You can help Misplaced Pages by expanding it.

Glycogenesis and glycogenolysis metabolic intermediates
Glucose
Uridine
Other
Fructose and galactose metabolic intermediates
Fructose
Galactose
Mannose
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