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Ama is a Sanskrit word literally meaning "uncooked" or "undigested".
In ayurveda, ama is used as a technical word for anything that exists in a state of incomplete transformation. In particular, it can refer to a toxic byproduct generated due to improper or incomplete digestion. The concept does not have a direct equivalent in standard medicine. Toxins that were produced at any stage of metabolism and that are circulating through the channels are also sometimes called ama. The first stage of any disease is also frequently called ama.
References
Kacera, Walter (2007). "Ama and Disease". Ayurvedic Tongue Diagnosis. Lotus Press. pp. 159–176. ISBN9780940985773.