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'''Brain-specific angiogenesis inhibitor 3''' is a ] that in humans is encoded by the ''BAI3'' ].<ref name="pmid9533023">{{cite journal | author = Shiratsuchi T, Nishimori H, Ichise H, Nakamura Y, Tokino T | title = Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1) | journal = Cytogenet Cell Genet | volume = 79 | issue = 1-2 | pages = 103–8 | |
'''Brain-specific angiogenesis inhibitor 3''' is a ] that in humans is encoded by the ''BAI3'' ].<ref name="pmid9533023">{{cite journal | author = Shiratsuchi T, Nishimori H, Ichise H, Nakamura Y, Tokino T | title = Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1) | journal = Cytogenet Cell Genet | volume = 79 | issue = 1-2 | pages = 103–8 |date=Apr 1998 | pmid = 9533023 | pmc = | doi =10.1159/000134693 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: BAI3 brain-specific angiogenesis inhibitor 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=577| accessdate = }}</ref> | ||
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Revision as of 12:34, 15 January 2014
Template:PBB Brain-specific angiogenesis inhibitor 3 is a protein that in humans is encoded by the BAI3 gene.
The adhesion GPCR BaI3 is an orphan receptor that has a long N-terminus consisting of one cub domain, five BaI Thrombospondin type 1 repeats, and one hormone binding domain. BaI3 is expressed in neural tissues of the central nervous system. BaI3 has been shwon to have a high affinity for C1q proteins. C1q added to hippocampal neurons expressing BaI3 resulted in a decrease in the number of synapses.
References
- Shiratsuchi T, Nishimori H, Ichise H, Nakamura Y, Tokino T (Apr 1998). "Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1)". Cytogenet Cell Genet. 79 (1–2): 103–8. doi:10.1159/000134693. PMID 9533023.
{{cite journal}}
: CS1 maint: multiple names: authors list (link) - "Entrez Gene: BAI3 brain-specific angiogenesis inhibitor 3".
- Marc F. Bolliger, David C. Martinelli, and Thomas C. Südhof. The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins. PNAS 2011 ; published ahead of print January 24, 2011, doi:10.1073/pnas.1019577108
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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