Hymecromone: Difference between revisions

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	\| C=10 \| H=8 \| O=3		\| C=10 \| H=8 \| O=3
	\| molecular_weight = 176.17 g/mol
	\| smiles = CC1=CC(=O)OC2=C1C=CC(=C2)O		\| smiles = CC1=CC(=O)OC2=C1C=CC(=C2)O
	\| StdInChI_Ref = {{stdinchicite\|correct\|chemspider}}		\| StdInChI_Ref = {{stdinchicite\|correct\|chemspider}}

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Pharmaceutical compound

Hymecromone
Clinical data

Other names	4-Methylumbelliferone
AHFS/Drugs.com	International Drug Names
ATC code	A05AX02 (WHO)
Identifiers
IUPAC name 7-Hydroxy-4-methylchromen-2-one
CAS Number	90-33-5
PubChem CID	5280567
DrugBank	DB07118
ChemSpider	4444190
UNII	3T5NG4Q468
KEGG	D00170
ChEBI	CHEBI:17224
ChEMBL	ChEMBL12208
CompTox Dashboard (EPA)	DTXSID8025670
ECHA InfoCard	100.001.806
Chemical and physical data
Formula	C₁₀H₈O₃
Molar mass	176.171 g·mol
3D model (JSmol)	Interactive image
SMILES CC1=CC(=O)OC2=C1C=CC(=C2)O
InChI InChI=1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3 Key:HSHNITRMYYLLCV-UHFFFAOYSA-N
(verify)

Hymecromone (4-methylumbelliferone) is a drug used in bile therapy. It is used as choleretic and antispasmodic drugs and as a standard for the fluorometric determination of enzyme activity.

Hymecromone is a crystalline solid with a melting point of 194–195 °C. It is soluble in methanol and glacial acetic acid.

References

Yang, Yongsok, and Kozo Hamaguchi. "Hydrolysis of 4-methylumbelliferyl N-acetyl-chitotriosidase catalyzed by hen and turkey lysozymes: pH dependence of the kinetic constants." The Journal of Biochemistry 87.4 (1980): 1003-1014.

v t e Bile and liver therapy (A05)
Bile therapy	bile acid Chenodeoxycholic acid Cholic acid Obeticholic acid Ursodeoxycholic acid Ursodoxicoltaurine Cyclobutyrol Elafibranor Hymecromone Maralixibat chloride Menbutone Nicotinyl methylamide Odevixibat Piprozolin Seladelpar
Liver therapy	Arginine glutamate Citiolone Epomediol Glycyrrhizin Metadoxine Methionine Ornithine oxoglutarate Phospholipids Resmetirom Silymarin Tidiacic arginine