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	Immune system is a featured article; it (or a previous version of it) has been identified as one of the best articles produced by the Misplaced Pages community. Even so, if you can update or improve it, please do so.
	This article appeared on Misplaced Pages's Main Page as Today's featured article on March 1, 2007, and on December 30, 2020.
Article milestones Date Process Result November 6, 2006 Peer review Reviewed January 9, 2007 Featured article candidate Promoted
Current status: Featured article

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Template:WikiProject Molecular and Cellular Biology Please add the quality rating to the {{WikiProject banner shell}} template instead of this project banner. See WP:PIQA for details. Anatomy: Systems Top‑importance This article is within the scope of WikiProject Anatomy, a collaborative effort to improve the coverage of Anatomy on Misplaced Pages. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.AnatomyWikipedia:WikiProject AnatomyTemplate:WikiProject AnatomyAnatomy Top This article has been rated as Top-importance on the project's importance scale. This article has been classified as relating to systems. Please add the quality rating to the {{WikiProject banner shell}} template instead of this project banner. See WP:PIQA for details. Animal anatomy Top‑importance This article is part of WikiProject Animal anatomy, an attempt to organise a detailed guide to all topics related to animal anatomy apart from human anatomy. To participate, you can edit the attached article, or contribute further at WikiProject Animal anatomy. This project is an offshoot of WikiProject AnimalsAnimal anatomyWikipedia:WikiProject Animal anatomyTemplate:WikiProject Animal anatomyAnimal anatomy Top This article has been rated as Top-importance on the project's importance scale. Please add the quality rating to the {{WikiProject banner shell}} template instead of this project banner. See WP:PIQA for details. Systems Mid‑importance This article is within the scope of WikiProject Systems, which collaborates on articles related to systems and systems science.SystemsWikipedia:WikiProject SystemsTemplate:WikiProject SystemsSystems Mid This article has been rated as Mid-importance on the project's importance scale. This article is within the field of Systems. Template:Vital article Template:WP1.0

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This article is substantially duplicated by a piece in an external publication. Since the external publication copied Misplaced Pages rather than the reverse, please do not flag this article as a copyright violation of the following sources: Miller, F. P., Vandome, A. F., & McBrewster, J. (2010), Fish diseases and parasites: Disease, parasitism, pathogen, epidermis (skin), microorganism, inflammation, white blood cell, immune system, vaccine, aquaculture, aquarium fish, Alphascript Publishing{{citation}}: CS1 maint: multiple names: authors list (link) Miller, F. P., Vandome, A. F., & McBrewster, J. (2009), Introduction to viruses: Introduction to genetics, viral life cycle, viral entry, plant pathology, bacteriophage, Iinate immune system, immune system, vaccination, antiviral drug, rotavirus, norovirus, Alphascript Publishing{{citation}}: CS1 maint: multiple names: authors list (link) Additional comments OCLC 688486716, ISBN 9786130279011. This article has been mentioned by a media organization: Ed Yong (September 2017). "Yo contengo multitudes. (in English) I Contain Multitudes ISBN 978-84-9992-766-4, page 106". PenguinRandom House Grupo Editorial, S.A.U. Retrieved 29 December 2018. Mientras escribo esto, Misplaced Pages todavía define el sistema inmunitario como «un sistema de estructuras y procesos biológicos dentro de un organismo que protege contra la enfermedad». Sin embargo, para muchos científicos, la protección contra los patógenos es solo una ventaja adicional. La función principal del sistema inmunitario es administrar nuestras relaciones con los microbios residentes en nosotros.

MEDDATE

Just leaving a note here about the age of some of the books: WP:MEDDATE prefers recent sources, and anyone who's worked much on medicine-related articles has probably had the experience of someone reverting their additions because the source is more than 5 or 10 years old.

There was a discussion about this at Misplaced Pages talk:WikiProject Medicine, and we agreed that it was acceptable to cite high-quality older sources for the specific basic, unchanging content (e.g., names of cells) in question, and in one case, to cite a high-quality older source that was freely available to readers than to cite the paywalled newer versions that are available to a couple of editors. This should therefore be considered in compliance with WP:MEDRS's advice on sources. WhatamIdoing (talk) 17:47, 2 December 2020 (UTC)

I think there's an important distinction between an older, quality source that has been in place for a decade, and an older source that someone is trying to add fresh (particularly when newer, updated sources are available). An admirable goal would be to have all of our medical content sourced to recent high-quality sources, but we have limited editor resources and it sometimes feels like sticking your thumb in the dyke: I'd be satisfied if I thought the number of older sources at least wasn't increasing. --RexxS (talk) 19:27, 2 December 2020 (UTC)

Image for "Helper T cells" subsection

This image is problematic for reasons I stated above in Image review. I'm tempted to create a diagram showing a CD4+ T cell at center, with an array of functions depicted around it - in the 4 corners, perhaps - cytotoxic ("killer") CD8+ T cell licensing, delayed type hypersensitivity using interferon gamma and granulomatous inflammation as a really important example (it's the basis of the Mantoux test for latent TB), B cell help in the germinal center reaction (the basis for conjugate vaccines that have been so dramatically effective, and the regulatory T cell role. I'll do my best to make it as simple/accessible as desired. Any thoughts? — soupvector (talk) 02:16, 4 December 2020 (UTC)

Yes. Thanks. Are you considering something like this ? Graham Beards (talk) 08:42, 4 December 2020 (UTC)

Yes, figure 2 in that paper is the sort of thing I was thinking of, but is a bit more detailed perhaps than we need for this article. — soupvector (talk) 13:41, 4 December 2020 (UTC)

Excellent. Thanks. Graham Beards (talk) 18:33, 4 December 2020 (UTC)

Cell structure addition

Graham Beards this appears to be a COI addition; is it needed, and is it in the right place? SandyGeorgia (Talk) 15:44, 15 December 2020 (UTC)

PS, if I am unable to decipher why this content is there, perhaps our readers won't either. And the last sentence is uncited, just as we are asking Wehwalt to have a look as to swapping this in to TFA ... and it's a one-paragraph section. SandyGeorgia (Talk) 15:51, 15 December 2020 (UTC)

It's WP:RECENT that can be deleted. I agree, it doesn't help the reader.Graham Beards (talk) 16:40, 15 December 2020 (UTC)

Concern raised at WP:ERRORS

Please see here. I'd be grateful if someone would post a response there, though much of it may be a matter for this talk page.--Wehwalt (talk) 13:21, 30 December 2020 (UTC)

I don't regard any of the concerns to be errors.

• With regard to the use of the definite article, this is what our sources use; see for example: Sompayrac L (2019). How the immune system works. Hoboken, NJ: Wiley-Blackwell. ISBN 978-1-119-54212-4. OCLC 1083261548. (my emphasis).
• As for the use of the word "diseases". The immune system is not only important in "infectious disease" and "damage", among others in plays a role in embryology. I think, for the Lead, it's ok to lack a little precision here.
• It's not really a medical topic; it's biology.
• "The figure legend contains no errors. But an improved legend could be proposed on the article's Talk Page.
• The "other mechanisms that protect us from harm" have nothing at all to do with immunity. We draw the line where our sources do. Again see Sompayrac.
• The article is stable, and has been for years. The improvements and updates that have been made for its second time as TFA, should not be regarded as symptom of instability.

Graham Beards (talk) 15:16, 30 December 2020 (UTC)

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