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Isomigrastatin

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Isomigrastatin
Names
IUPAC name 4--piperidine-2,6-dione
Identifiers
CAS Number
3D model (JSmol)
CompTox Dashboard (EPA)
SMILES
  • C((/(C)=C/(C(CCCC2CC(NC(C2)=O)=O)=O)C)O1)(O)(OC)/C=C/CC/C=C/C1=O
Properties
Chemical formula C27H39NO7
Molar mass 489.60 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkverify (what is  ?) Infobox references
Chemical compound

Isomigrastatin is an analogue of migrastatin, an organic compound that naturally occurs in the Streptomyces platensis bacteria. Isomigrastatin has shown promise as a drug in the treatment of cancer. A laboratory synthesis was reported in 2007.

References

  1. Krauss, IJ; et al. (2007). "Total Synthesis of (+)-Isomigrastatin". Angewandte Chemie. 46 (29): 5576–5579. doi:10.1002/anie.200701837. PMID 17583888. {{cite journal}}: Explicit use of et al. in: |author= (help)


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