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Condensation reaction

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A condensation reaction is a class of an organic addition reaction that proceeds in a step-wise fashion to produce the addition product, usually in equilibrium, and a water molecule (hence named condensation). The reaction may otherwise involve the functional groups of the molecule and formation of ammonia, ethanol, or acetic acid. It is a versatile class of reactions that can occur in acidic or basic conditions or in the presence of a catalyst. This class of reactions is a vital part of life as it is essential to the formation of peptide bonds between amino acids and the biosynthesis of fatty acids.

Many variations of condensation reactions exist, common examples include the aldol condensation, Claisen condensation, Knoevenagel condensation, and the Dieckman condensation (intramolecular Claisen condensation).

Condensation reaction between two symmetrical aldehydes. The final product is formed irreversibly due to stability from the conjugation of the double bonds

See also

References

  1. Fakirov, S. (2019-02-01). "Condensation Polymers: Their Chemical Peculiarities Offer Great Opportunities". Progress in Polymer Science. 89: 1–18. doi:10.1016/j.progpolymsci.2018.09.003. ISSN 0079-6700.
  2. "Condensation Reaction". IUPAC Copendium of Chemical Terminology (Gold Book). IUPAC. Retrieved 7 December 2017.
  3. Voet, Donald; Voet, Judith; Pratt, Chriss (2008). Fundamentals of Biochemistry. Hoboken, NJ: John Wiley & Sons, Inc. p. 88. ISBN 978-0470-12930-2.
  4. Bruckner, Reinhard (2002). Advanced Organic Chemistry (First ed.). San Diego, California: Harcourt Academic Press. pp. 414–427. ISBN 0-12-138110-2.
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