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Creatine ethyl ester

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Revision as of 13:16, 29 October 2010 by Beetstra (talk | contribs) (Script assisted update of identifiers from ChemSpider, CommonChemistry and FDA for the Chem/Drugbox validation project - Updated: ChemSpiderID PubChem InChI1 InChIKey1 SMILES1.)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) "CE2" redirects here. For the French elementary school grade, see Education in France.
Creatine ethyl ester
Names
IUPAC name Ethyl N-(aminoiminomethyl)-N-methylglycine
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
PubChem CID
CompTox Dashboard (EPA)
InChI
  • InChI=1/C6H13N3O2/c1-3-11-5(10)4-9(2)6(7)8/h3-4H2,1-2H3,(H3,7,8)Key: UFUWQSYRGLMLKP-UHFFFAOYAK
SMILES
  • NC(N(C)CC(OCC)=O)=N
  • O=C(OCC)CN(C(=)N)C
Properties
Chemical formula C6H13N3O2
Molar mass 159.19 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

Creatine ethyl ester, also known as creatine ester, cre-ester and CEE, is a substance sold as an aid for athletic performance and for muscle development in bodybuilding. It is an ethyl ester derivative of creatine, from which it is made. In the body, CEE is converted back into creatine. CEE is said to have a much better absorption rate and a longer half-life in the body than regular creatine monohydrate, because it is slightly more lipophilic. However, in a published study comparing the two, CEE was not as effective at increasing serum and muscle creatine levels or in improving body composition, muscle mass, strength, and power.

As a supplement, the compound was developed, patented and licensed through UNeMed, the technology transfer entity of the University of Nebraska Medical Center, and is sold under numerous brand names.

References

  1. Spillane, Mike; Schoch, Ryan; Cooke, Matt; Harvey, Travis; Greenwood, Mike; Kreider, Richard; Willoughby, Darryn S (2009). "The effects of creatine ethyl ester supplementation combined with heavy resistance training on body composition, muscle performance, and serum and muscle creatine levels". Journal of the International Society of Sports Nutrition. 6: 6. doi:10.1186/1550-2783-6-6. PMC 2649889. PMID 19228401.{{cite journal}}: CS1 maint: unflagged free DOI (link)
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