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Amlodipine/benazepril

Combination of
Amlodipine	Calcium channel blocker
Benazepril	ACE inhibitor
Clinical data
Routes of administration	Oral
ATC code	None
Legal status
Legal status	US: ℞-only
Identifiers
PubChem CID	5746247
ChemSpider	4676979
CompTox Dashboard (EPA)	DTXSID20189285
Chemical and physical data
3D model (JSmol)	Interactive image
SMILES Clc1ccccc1C2C(\C(=O)OC)=C(/N\C(=C2\C(=O)OCC)COCCN)C.O=C(OCC)(N2C(=O)N(c1ccccc1CC2)CC(=O)O)CCc3ccccc3
InChI InChI=1S/C24H28N2O5.C20H25ClN2O5/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28;1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h3-11,19-20,25H,2,12-16H2,1H3,(H,27,28);5-8,17,23H,4,9-11,22H2,1-3H3/t19-,20-;/m0./s1 Key:SRTZYSFUFGOMFR-FKLPMGAJSA-N
(verify)

Amlodipine/benazepril, marketed in the U.S. as Lotrel by Novartis and manufactured as a generic drug by Teva and Sandoz, is an antihypertensive medication which combines a calcium channel blocker (amlodipine besilate) with an angiotensin converting enzyme inhibitor (benazepril). This drug, like similar combinations, is prescribed when either agent alone is not sufficient to bring a person's blood pressure down to target range. As a combination agent, Lotrel shares the adverse reaction profile of both of its individual parts.

See also

• Amlodipine
• Benazepril

References

1. Lotrel Prescribing Information

External links

• Novartis: Lotrel official website
• Drugs.com: Lotrel
• RxList.com: Lotrel

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