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Isomigrastatin

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Isomigrastatin
Names
IUPAC name 4--piperidine-2,6-dione
Identifiers
CAS Number
3D model (JSmol)
CompTox Dashboard (EPA)
SMILES
  • C((/(C)=C/(C(CCCC2CC(NC(C2)=O)=O)=O)C)O1)(O)(OC)/C=C/CC/C=C/C1=O
Properties
Chemical formula C27H39NO7
Molar mass 489.60 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

Isomigrastatin is an analogue of migrastatin, an organic compound that naturally occurs in the Streptomyces platensis bacteria. Isomigrastatin has shown promise as a drug in the treatment of cancer. A laboratory synthesis was reported in 2007.

References

  1. Krauss, IJ; et al. (2007). "Total Synthesis of (+)-Isomigrastatin". Angewandte Chemie. 46 (29): 5576–5579. doi:10.1002/anie.200701837. PMID 17583888. {{cite journal}}: Explicit use of et al. in: |author= (help)


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