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Cymarin

Clinical data
Other names	Cymarine; K-Strophanthin-α; NSC 7522; Strophantin K; WV 90043a; k-Strophanthin-α
ATC code	C01AC03 (WHO)
Identifiers
IUPAC name (3S,5S,8R,10S,13R,14S,17R)-5,14-dihydroxy-3-((2R,4S,5S,6R)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yloxy)-13-methyl-17-(5-oxo-2,5-dihydrofuran-3-yl)hexadecahydro-1H-cyclopentaphenanthrene-10-carbaldehyde
CAS Number	508-77-0
PubChem CID	10504
UNII	UK3LS8435E
ChEMBL	ChEMBL1651908
CompTox Dashboard (EPA)	DTXSID20871714
ECHA InfoCard	100.007.353
Chemical and physical data
Formula	C30H44O9
Molar mass	548.665 g/mol g·mol
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Cymarin (or cymarine) is a cardiac glycoside. Apocynum cannabinum used as a source of fiber by Native Americans and Apocynum venetum (Chinese: 羅布麻) used as a herbal tea in China both contain cymarin. Cymarin is a cardiogenic toxin that causes cardiac arrhythmia in humans. Cymarin is used in modern medicine in formulated pharmaceutical preparations used to treat a variety of tumors.

References

1. Edible and Medicinal plants of the West, Gregory L. Tilford, ISBN 0-87842-359-1
2. The Merck Index, 12th Edition, 2830

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