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Ama in Ayurveda is a toxic byproduct generated due to improper or imcomplete digestion. It is unknown of there is any equivalent concept for this in standard scientific medicine.
After waking up in morning, one should clean his/her tongue. The whitish coating which appears on tongue is said Ama, as per Ayurveda, coming from stomach. This Ama channels into blood veins when it stays for longer periods in stomach. Then, this Ama flows with blood inside all body parts. If this Ama penetrates any body part like knee joint then slowly related problems arises. So, as per Ayurveda , Ama should be minimised in the body. The best way to increase digestive power is by eating ginger some 5-10 minutes before meals.
Otherwise, Ama should be removed from the stomach by avoiding any constipation.
Ayurveda, even teaches that one's body should be Niram ( Nir + Ama ) i.e. free from Ama to remove problem causes from the root effectively.