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Mitoguazone

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This is the current revision of this page, as edited by Entranced98 (talk | contribs) at 23:32, 5 April 2023 (Importing Wikidata short description: "Chemical compound"). The present address (URL) is a permanent link to this version.

Revision as of 23:32, 5 April 2023 by Entranced98 (talk | contribs) (Importing Wikidata short description: "Chemical compound")(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) Chemical compound Pharmaceutical compound
Mitoguazone
Clinical data
Other names2-amino]guanidine
ATC code
Identifiers
IUPAC name
  • (2E,2'E)-2,2'-(1E,2E)-propane-1,2-diylidenedihydrazinecarboximidamide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
CompTox Dashboard (EPA)
ECHA InfoCard100.121.515 Edit this at Wikidata
Chemical and physical data
FormulaC5H12N8
Molar mass184.207 g·mol
3D model (JSmol)
SMILES
  • C\C(\C=N\NC(N)=N)=N/NC(N)=N
InChI
  • InChI=1S/C5H12N8/c1-3(11-13-5(8)9)2-10-12-4(6)7/h2H,1H3,(H4,6,7,12)(H4,8,9,13)/b10-2+,11-3+
  • Key:PKDBCJSWQUOKDO-UHFFFAOYSA-M
  (what is this?)  (verify)

Mitoguazone (also known as methylglyoxal bis(guanylhydrazone) or MGBG) is a drug used in chemotherapy.

References

  1. Hoffmann H, Gutsche W, Amlacher R, Schulze W, Werner W, Lenk H, Wohlrab W, Haupt E (1989). "". Archiv für Geschwulstforschung (in German). 59 (2): 135–48. PMID 2655552.
Intracellular chemotherapeutic agents / antineoplastic agents (L01)
SPs/MIs
(M phase)
Block microtubule assembly
Block microtubule disassembly
DNA replication
inhibitor
DNA precursors/
antimetabolites
(S phase)
Folic acid
Purine
Pyrimidine
Deoxyribonucleotide
Topoisomerase inhibitors
(S phase)
I
II
II+Intercalation
Crosslinking of DNA
(CCNS)
Alkylating
Platinum-based
Nonclassical
Intercalation
Photosensitizers/PDT
Other
Enzyme inhibitors
Receptor antagonists
Other/ungrouped


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