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Urtoxazumab

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This is the current revision of this page, as edited by Entranced98 (talk | contribs) at 23:49, 5 April 2023 (Adding local short description: "Monoclonal antibody", overriding Wikidata description "chemical compound"). The present address (URL) is a permanent link to this version.

Revision as of 23:49, 5 April 2023 by Entranced98 (talk | contribs) (Adding local short description: "Monoclonal antibody", overriding Wikidata description "chemical compound")(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) Monoclonal antibody Pharmaceutical compound
Urtoxazumab
Monoclonal antibody
TypeWhole antibody
SourceHumanized (from mouse)
TargetE. coli Shiga-like toxin II B subunit
Clinical data
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
Chemical and physical data
FormulaC6414H9934N1718O2010S40
Molar mass144556.44 g·mol
  (what is this?)  (verify)

Urtoxazumab is a humanized monoclonal antibody against diarrhoea caused by Escherichia coli, serotype O121. The drug is designed to bind to a toxin of this bacterium, so that it can be more easily broken down and eliminated from the body.

References

  1. "International Nonproprietary Names for Pharmaceutical Substances (INN)" (PDF). World Health Organization.
  2. López EL, Contrini MM, Glatstein E, González Ayala S, Santoro R, Allende D, et al. (January 2010). "Safety and pharmacokinetics of urtoxazumab, a humanized monoclonal antibody, against Shiga-like toxin 2 in healthy adults and in pediatric patients infected with Shiga-like toxin-producing Escherichia coli". Antimicrobial Agents and Chemotherapy. 54 (1): 239–43. doi:10.1128/AAC.00343-09. PMC 2798559. PMID 19822704.
Monoclonal antibodies for infectious disease and toxins
Fungal
Human
Viral
Human
Chimeric
Humanized
Bacterial
Human
Mouse
Chimeric
Humanized
Toxin
Human
Chimeric
Humanized
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