Pipecuronium bromide - Misplaced Pages

This is the current revision of this page, as edited by Citation bot (talk | contribs) at 06:58, 17 July 2024 (Add: isbn, pmid. | Use this bot. Report bugs. | Suggested by Whoop whoop pull up | Category:Bromides | #UCB_Category 140/180). The present address (URL) is a permanent link to this version.

Pharmaceutical compound

Pipecuronium bromide
Clinical data


Trade names	Arduan
AHFS/Drugs.com	International Drug Names
ATC code	M03AC06 (WHO)
Identifiers
IUPAC name (2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2,16-bis(4,4-dimethylpiperazin-4-ium-1-yl)androstane dibromide
CAS Number	52212-02-9 68399-58-6
PubChem CID	65332
ChemSpider	58815
UNII	R6ZTY81RE1
KEGG	D00764
ChEMBL	ChEMBL1200722
CompTox Dashboard (EPA)	DTXSID8023478
ECHA InfoCard	100.052.475
Chemical and physical data
Formula	C₃₅H₆₂Br₂N₄O₄
Molar mass	762.713 g·mol
3D model (JSmol)	Interactive image
SMILES ..O=C(O6(N1CC(C)(C)CC1)C56(C)CC35CC4C(OC(=O)C)(N2CC(CC2)(C)C)C34C)C
InChI InChI=1S/C35H62N4O4.2BrH/c1-24(40)42-32-21-26-9-10-27-28(35(26,4)23-31(32)37-15-19-39(7,8)20-16-37)11-12-34(3)29(27)22-30(33(34)43-25(2)41)36-13-17-38(5,6)18-14-36;;/h26-33H,9-23H2,1-8H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1 Key:TXWBOBJCRVVBJF-YTGGZNJNSA-L
(what is this?) (verify)

Pipecuronium (Arduan) is a bisquaternary aminosteroid muscle relaxant which blocks nicotinic acetylcholine receptors at the neuromuscular junction. It is also an antagonist of M2 and M3 muscarinic receptors and is the most potent neuromuscular blocking agent of the aminosteroid class.

It is sold under the trade names Arduan and Pycuron.

References

"Pipecuronium Bromide". WHOCC - ATC/DDD Index. M03AC06.
^ "Pipecuronium". DrugBank.
Singh H, Jindal DP, Yadav MR, Kumar M (January 1991). "5 Heterosteroids and drug research.". Progress in Medicinal Chemistry. Vol. 28. pp. 233-300 (270). doi:10.1016/S0079-6468(08)70366-7. ISBN 978-0-444-81275-9. PMID 1843548.
"Pipecuronium - brand name list from". Drugs.com. Retrieved 2022-09-17.

Carbamic acid esters	Carisoprodol Cyclarbamate Difebarbamate Febarbamate Meprobamate Phenprobamate Styramate Tybamate
Benzodiazepines	Bromazepam Diazepam Clonazepam Flunitrazepam Lorazepam Nitrazepam Temazepam Tetrazepam
Nonbenzodiazepines	Eszopiclone
Thienodiazepines	Etizolam
Quinazolines	Methaqualone
Anticholinergics (Antimuscarinics)	Cyclobenzaprine Orphenadrine
Other	Arbaclofen placarbil Baclofen Chlormezanone Chlorphenesin Chlorzoxazone Eperisone Fenyramidol Flopropione Gabapentin GHB Inaperisone Lanperisone Mephenesin Mephenoxalone Metaxalone Methocarbamol Phenibut Pregabalin Pridinol Promoxolane Quinine Silperisone Thiocolchicoside Tizanidine Tolperisone Zoxazolamine

nAChRsTooltip Nicotinic acetylcholine receptors

Agonists
(and PAMsTooltip positive allosteric modulators)

Antagonists
(and NAMsTooltip negative allosteric modulators)

See also: Receptor/signaling modulators; Muscarinic acetylcholine receptor modulators; Acetylcholine metabolism/transport modulators

This article about a steroid is a stub. You can help Misplaced Pages by expanding it.

This drug article relating to the musculoskeletal system is a stub. You can help Misplaced Pages by expanding it.