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Isoaminile

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	R05DB04 (WHO)
Identifiers
IUPAC name 4-(dimethylamino)-2-isopropyl-2-phenylpentanenitrile
CAS Number	77-51-0
PubChem CID	6481
DrugBank	DB08944
ChemSpider	6236
UNII	R4823W2PQL
KEGG	D08088
CompTox Dashboard (EPA)	DTXSID5057830
ECHA InfoCard	100.000.940
Chemical and physical data
Formula	C16H24N2
Molar mass	244.382 g·mol
3D model (JSmol)	Interactive image
SMILES N#CC(c1ccccc1)(C(C)C)CC(N(C)C)C
InChI InChI=1S/C16H24N2/c1-13(2)16(12-17,11-14(3)18(4)5)15-9-7-6-8-10-15/h6-10,13-14H,11H2,1-5H3 Key:WFLSCFISQHLEED-UHFFFAOYSA-N
(what is this?)  (verify)

Isoaminile is an antitussive (cough suppressant) used under the trade-name Peracon.

The normal therapeutic dose is 40–80 mg of the cyclamate salt, with a maximum of five doses in a 24-hour period. In addition to its central antitussive effects, it is also an anticholinergic, exhibiting both antimuscarinic and antinicotinic actions.

References

1. ^ Chappel CI, von Seeman C (1963). "Antitussive Drugs". In Ellis GP, West GB (eds.). Progress in Medicinal Chemistry. Vol. 3. Butterworth. pp. 114–115. doi:10.1016/S0079-6468(08)70117-6. ISBN 978-0-444-53322-7. PMID 14146305. Retrieved 2013-09-12.

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• Dimethylamino compounds
• Nitriles
• Antitussives
• Isopropyl compounds
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