Misplaced Pages

Kynuramine

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.

This is an old revision of this page, as edited by Citation bot (talk | contribs) at 16:02, 24 December 2024 (Add: doi-access, pmid, pages, issue, volume, journal, date, title, authors 1-8. | Use this bot. Report bugs. | Suggested by Innerstream | #UCB_toolbar). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Revision as of 16:02, 24 December 2024 by Citation bot (talk | contribs) (Add: doi-access, pmid, pages, issue, volume, journal, date, title, authors 1-8. | Use this bot. Report bugs. | Suggested by Innerstream | #UCB_toolbar)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff)
Kynuramine
Names
IUPAC name 3-Amino-1-(2-aminophenyl)propan-1-one
Other names Diaminopropiophenone
Identifiers
CAS Number
3D model (JSmol)
PubChem CID
CompTox Dashboard (EPA)
SMILES
  • C1=CC=C(C(=C1)C(=O)CCN)N
Properties
Chemical formula C9H12N2O
Molar mass 164.208 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

Kynuramine is a chemical compound with the molecular formula C9H12N2O. It is the prototypical member of the class of biogenic amines known collectively as kynuramines. Kynuramine is produced by the decarboxylation of kynurenine and is a metabolite of tryptophan.

Kynuramine is an α-adrenoceptor inhibitor.

In biochemistry, kynuramine has been used as a substrate in assays used to measure amine oxidase activity.

References

  1. ^ Hardeland, Rüdiger; Tan, Dun-Xian; Reiter, Russel J. (2009). "Kynuramines, metabolites of melatonin and other indoles: The resurrection of an almost forgotten class of biogenic amines". Journal of Pineal Research. 47 (2): 109–126. doi:10.1111/j.1600-079X.2009.00701.x. PMID 19573038.
  2. Ruddick, Jon P.; Evans, Andrew K.; Nutt, David J.; Lightman, Stafford L.; Rook, Graham A.W.; Lowry, Christopher A. (2006). "Tryptophan metabolism in the central nervous system: Medical implications". Expert Reviews in Molecular Medicine. 8 (20): 1–27. doi:10.1017/S1462399406000068. PMID 16942634.
  3. Johnson, Thomas D.; Clarke, David E. (1981). "An α-adrenoceptor inhibitory action of kynuramine". European Journal of Pharmacology. 72 (4): 351–356. doi:10.1016/0014-2999(81)90574-4. PMID 6115758.
  4. Massey, J.B.; Churchich, J.E. (1977). "Kynuramine, a fluorescent substrate and probe of plasma amine oxidase". Journal of Biological Chemistry. 252 (22): 8081–8084. doi:10.1016/S0021-9258(17)40939-2. PMID 562342.
  5. Matsumoto, T.; Suzuki, O.; Furuta, T.; Asai, M.; Kurokawa, Y.; Nimura, Y.; Katsumata, Y.; Takahashi, I. (1985). "A sensitive fluorometric assay for serum monoamine oxidase with kynuramine as substrate". Clinical Biochemistry. 18 (2): 126–129. doi:10.1016/S0009-9120(85)80094-1. PMID 4017223.
Categories: