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Revision as of 06:41, 22 July 2002 by Tobias Hoevekamp (talk | contribs) (-/talk)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff)Tricyclic antidepressants are a class of antidepressant drugs first used in the 1960s. Tricyclic antidepressants are not addictive. Although they remain effective, they have been increasingly replaced by SSRIs because the difference between a therapeutic and a toxic dose of a tricyclic antidepressant is small. Like monoamine oxidase inhibitors, this posed a difficulty for the physician in that they were prescribing a medication for a depressed person that could be used to commit suicide.