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Hemin

Clinical data
Routes of administration	Intravenous infusion
ATC code	B06AB01 (WHO)
Legal status
Legal status	US: ℞-only
Identifiers
IUPAC name chloroiron(III)
CAS Number	16009-13-5
PubChem CID	5318002
ChemSpider	21160444
UNII	743LRP9S7N
Chemical and physical data
Formula	C34H32ClFeN4O4
Molar mass	651.94 g/mol g·mol
3D model (JSmol)	Interactive image
SMILES OC(=O)CCC=5C1=C\C6=N\C(=C/c3n2(Cl)N1C(=C\C4=N\C(=C/c2c(C=C)c3C)C(/C)=C4/C=C)/C=5C)C(\C)=C6\CCC(O)=O
InChI InChI=1S/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16?;; Key:BTIJJDXEELBZFS-UKFHATERSA-K
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Hemin (trade name Panhematin) is an iron-containing porphyrin. More specifically, it is Protoporphyrin IX containing a ferric iron ion (Heme b) with a chloride ligand.

It is used in the management of porphyria attacks, particularly in acute intermittent porphyria.

It is sometimes distinguished from Hematin which has a hydroxide ligand in place of the chloride. However, the terms are sometimes equated.

Hematin is considered the "X factor" required for the growth of Haemophilus influenzae.

References

1. "hemin" at Dorland's Medical Dictionary
2. "hematin" at Dorland's Medical Dictionary
3. Sherris, John C.; Ryan, Kenneth J.; Ray, C. L. (2004). Sherris medical microbiology: an introduction to infectious diseases. New York: McGraw-Hill. p. 395. ISBN 0-8385-8529-9.{{cite book}}: CS1 maint: multiple names: authors list (link)

External links

• Information from the American Porphyria Foundation, including emergency delivery information
• Hemin at RxList
• Hemin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

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