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Indicaxanthin

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Indicaxanthin
Names
IUPAC name 4--2,3-dihydro-pyridine-2,6-dicarboxylic acid
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
PubChem CID
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C14H16N2O6/c17-12(18)9-6-8(7-10(15-9)13(19)20)3-5-16-4-1-2-11(16)14(21)22/h3,5-6,10-11H,1-2,4,7H2,(H3,17,18,19,20,21,22)/t10-,11-/m0/s1Key: RJIIQBYZGJSODH-QWRGUYRKSA-N
  • InChI=1/C14H16N2O6/c17-12(18)9-6-8(7-10(15-9)13(19)20)3-5-16-4-1-2-11(16)14(21)22/h3,5-6,10-11H,1-2,4,7H2,(H3,17,18,19,20,21,22)/t10-,11-/m0/s1Key: RJIIQBYZGJSODH-QWRGUYRKBB
SMILES
  • O=C(O)\C2=C\C(=C\C=1/(C()=O)CCC1)C(C(=O)O)N2
Properties
Chemical formula C14H16N2O6
Molar mass 308.29 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkY verify (what is  ?) Infobox references
Chemical compound

Indicaxanthin is a type of betaxanthin, a plant pigment present in beets, prickly pear cactus, and the red dragonfruit Hylocereus costaricensis. It is a powerful antioxidant.

Medical uses

It has been shown in a spectrophotometric study for patients with thalassemia, that indicaxanthin can reduce perferryl-Hb generated in solution from met-Hb and hydrogen peroxide, more effectively than either trolox (a vitamin E derivative) or vitamin C, possibly interfering with perferryl-Hb, a reactive intermediate in the hydroperoxide-dependent Hb degradation.

Indicaxanthin in antioxidant studies was more effective than Trolox at scavenging the ABTS cation radical.

See also

References

  1. Tesoriere L, Allegra M, Butera D, Gentile C, Livrea MA (2006). "Cytoprotective effects of the antioxidant phytochemical indicaxanthin in beta-thalassemia red blood cells". Free Radic. Res. 40 (7): 753–61. doi:10.1080/10715760600554228. PMID 16984002. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  2. Pubmed.gov Antioxidant activities of sicilian prickly pear (Opuntia ficus indica) fruit extracts and reducing properties of its betalains: betanin and indicaxanthin
Types of plant pigments
Betalains
Chlorophyll
Curcuminoids
Flavonoids
Carotenoids
Other
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