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Dihydromethysticin

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Dihydromethysticin
Chemical structure of dihydromethysticin
Names
IUPAC name (2S)-2--4-methoxy-2,3-dihydropyran-6-one
Identifiers
CAS Number
3D model (JSmol)
PubChem CID
CompTox Dashboard (EPA)
SMILES
  • COC1=CC(=O)OC(C1)CCC2=CC3=C(C=C2)OCO3
Properties
Chemical formula C15H16O5
Molar mass 276.28 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). checkverify (what is  ?) Infobox references
Chemical compound

Dihydromethysticin is one of the six major kavalactones found in the kava plant.

Pharmacology

Dihydromethysticin has marked activity on the induction of CYP3A23.

References

  1. Malani, Joji (2002-12-03). "Evaluation of the effects of Kava on the Liver" (PDF). Fiji School of Medicine. Retrieved 2009-09-04. {{cite journal}}: Cite has empty unknown parameter: |coauthors= (help)
  2. Ma, Yuzhong (2004 November). "Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23". Drug Metabolism and Disposition. 32 (11): 1317–1324. doi:10.1124/dmd.104.000786. PMID 15282211. {{cite journal}}: |access-date= requires |url= (help); Check date values in: |date= (help); Unknown parameter |coauthors= ignored (|author= suggested) (help)

See also

Kava
History
Chemical composition
Kavalactones
Flavokavains
Other
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