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EDMA

Clinical data
Routes of administration	Oral
ATC code	none
Legal status
Legal status	Uncontrolled (but may be covered under the Federal Analogue Act in the United States and under similar bills in other countries)
Identifiers
IUPAC name 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-methylpropan-2-amine
PubChem CID	24257269
ChemSpider	23553090
CompTox Dashboard (EPA)	DTXSID501027143
Chemical and physical data
Formula	C12H17NO2
Molar mass	207.269
3D model (JSmol)	Interactive image
SMILES CC(Cc1ccc2c(c1)OCCO2)NC
InChI InChI=1S/C12H17NO2/c1-9(13-2)7-10-3-4-11-12(8-10)15-6-5-14-11/h3-4,8-9,13H,5-7H2,1-2H3 Key:UJKWLAZYSLJTKA-UHFFFAOYSA-N
(verify)

3,4-Ethylenedioxy-N-methylamphetamine (EDMA; MDMC) is an entactogen drug of the amphetamine class. It is an analogue of MDMA where the methylenedioxy ring has been replaced by an ethylenedioxy ring. EDMA was first synthesized by Alexander Shulgin. In his book PiHKAL, the dosage is listed as 150–250 mg, and the duration listed as 3–5 hours. According to Shulgin, EDMA produces a bare threshold consisting of paresthesia, nystagmus, and hypnogogic imagery, with few to no other effects. Scientific research has demonstrated that EDMA acts as a non-neurotoxic serotonin releasing agent with moderately diminished potency relative to MDMA, and with negligible effects on dopamine release. Based on Shulgin's reports of essential inactivity at 150–250 mg, it may be more active at higher doses.

See also

• Ethylidenedioxyamphetamine
• Tetralinylaminopropane
• Naphthylaminopropane

References

1. ^ Ann Shulgin; Alexander Shulgin (1991). Pihkal: A Chemical Love Story. Transform Press. ISBN 0-9630096-0-5.{{cite book}}: CS1 maint: multiple names: authors list (link)
2. ^ McKenna DJ, Guan XM, Shulgin AT (1991). "3,4-Methylenedioxyamphetamine (MDA) analogues exhibit differential effects on synaptosomal release of 3H-dopamine and 3H-5-hydroxytryptamine". Pharmacology, Biochemistry, and Behavior. 38 (3): 505–12. doi:10.1016/0091-3057(91)90005-M. PMID 1829838. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)

External links

• EDMA entry in PiHKAL
• MDMC (EDMA) entry in PiHKAL • info

Template:PiHKAL

• Drugs not assigned an ATC code
• Amphetamines
• Benzodioxins
• Entactogens and Empathogens