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3-Methoxy-4-hydroxyphenylglycol

Names
IUPAC name 1-(4-Hydroxy-3-methoxyphenyl) ethane-1,2-diol
Other names MHPG
Identifiers
CAS Number	67423-45-4
3D model (JSmol)	Interactive image Interactive image
ChemSpider	10348
KEGG	C05594
MeSH	Methoxyhydroxyphenylglycol
PubChem CID	10805
CompTox Dashboard (EPA)	DTXSID20862142
InChI InChI=1S/C9H12O4/c1-13-9-4-6(8(12)5-10)2-3-7(9)11/h2-4,8,10-12H,5H2,1H3Key: FBWPWWWZWKPJFL-UHFFFAOYSA-N InChI=1/C9H12O4/c1-13-9-4-6(8(12)5-10)2-3-7(9)11/h2-4,8,10-12H,5H2,1H3Key: FBWPWWWZWKPJFL-UHFFFAOYAR
SMILES COC1=C(C=CC(=C1)C(CO)O)O Oc1ccc(cc1OC)C(O)CO
Properties
Chemical formula	C9H12O4
Molar mass	184.18918
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Y verify (what is  ?) Infobox references

3-Methoxy-4-hydroxyphenylglycol (MHPG, MOPEG) is a metabolite of norepinephrine degradation. In the brain, it is the principal norepinephrine metabolite. It is released into the blood and cerebrospinal fluid, and a blood sample of it may therefore be an indication of recent sympathetic nervous system activity.

Low levels of it in the blood and CSF are connected to Anorexia nervosa.

References

1. Increase in cerebrospinal fluid and plasma levels of 3-methoxy-4- hydroxyphenylglycol in acute stroke T Kanda, K Azuma, F Sakai and Y Tazaki. Department of Internal Medicine, School of Medicine, Kitasato University, Sagamihara, Japan.
2. Figure 11-4 in: Rod Flower; Humphrey P. Rang; Maureen M. Dale; Ritter, James M. (2007). Rang & Dale's pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-06911-5.{{cite book}}: CS1 maint: multiple names: authors list (link)

• Metabolism
• Polyols